Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kohei Ishimura"'
Autor:
Koichi Fujiwara, Kohei Ishimura, Hiroe Suzuki, Takahisa Otsuka, Hayato Fukuda, Natsuko Hitora-Imamura, Masabumi Minami, Satoshi Deyama, Satoshi Shuto
Publikováno v:
Biological & pharmaceutical bulletin. 44(10):1548-1550
The antidepressant effect of eicosapentaenoic acid-derived bioactive lipid, resolvin E1 (RvE1), was examined in a murine model of chronic pain-induced depression using a tail suspension test. Because RvE1 reportedly possesses agonistic activity on a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::109e3aba07d0e08d3221bc2fab6f38fc
http://hdl.handle.net/2115/83324
http://hdl.handle.net/2115/83324
Autor:
Jun Ishihara, Tadashi Matsuda, Koki Hirashima, Mizuki Watanabe, Satoshi Shuto, Kohei Ishimura, Ryuta Muromoto, Yuto Murakami, Hayato Fukuda, Koichi Fujiwara
Publikováno v:
ACS Med Chem Lett
[Image: see text] RvE1 (1) is an endogenous lipid mediator with very potent anti-inflammatory activity, which is due to the inhibition of neutrophil chemotaxis and inflammatory cytokine production and the promotion of macrophage phagocytosis. On the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f0744efd940946db500b5e587a247c3
http://hdl.handle.net/2115/83926
http://hdl.handle.net/2115/83926
The antidepressant-like effect of resolvin E1 in repeated prednisolone-induced depression model mice
Autor:
Masabumi Minami, Satoshi Deyama, Shun Aoki, Kohei Ishimura, Katsuyuki Kaneda, Satoshi Shuto, Hayato Fukuda, Rinako Sugie
Publikováno v:
Behavioural brain research. 418
Resolvin E1 (RvE1) is an anti-inflammatory lipid mediator derived from eicosapentaenoic acid . We previously demonstrated that intracerebroventricular (i.c.v.) and intra-medial prefrontal cortex (mPFC) infusions of RvE1 produce antidepressant-like ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::077ae0613b7352af5e4af95cc0282886
https://pubmed.ncbi.nlm.nih.gov/34801580
https://pubmed.ncbi.nlm.nih.gov/34801580
Autor:
Haruka Aoki-Saito, Koichi Fujiwara, Jun Ishihara, Koki Hirashima, Hayato Fukuda, Hiroyuki Ikeda, Satoshi Shuto, Mizuki Watanabe, Tadashi Matsuda, Kohei Ishimura, Takeshi Hisada, Ryuta Muromoto
Publikováno v:
The Journal of organic chemistry. 85(21)
We synthesized RvE3 and its deoxy derivatives, 17-deoxy-RvE3 and 18-deoxy-RvE3, by a common route via Sonogashira coupling as a key step. The evaluation of their anti-inflammatory activities revealed that 18-deoxy-RvE3 was remarkably more potent than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f30345bd962890880671c61b0d1137
https://pubmed.ncbi.nlm.nih.gov/32942849
https://pubmed.ncbi.nlm.nih.gov/32942849
Autor:
Yoshinori Sato, Satoshi Shuto, Hiroyuki Ikeda, Mizuki Watanabe, Yuka Unno, Shigeru Tansho-Nagakawa, Hayato Fukuda, Tsuneyuki Ubagai, Yasuo Ono, Kohei Ishimura
Publikováno v:
FEBS Letters. 592:2706-2715
E-series resolvins are biosynthesized from eicosapentaenoic acid during the resolution phase of acute inflammation and enhance inflammation resolution. However, the role of E-series resolvins in inflammation resolution is not yet known. Herein, we sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06464a68aa8ac006f3b88263a867cebf
https://doi.org/10.1002/1873-3468.13215
https://doi.org/10.1002/1873-3468.13215
Autor:
Tadashi Matsuda, Satoshi Shuto, Jun Ishihara, Koki Hirashima, Hayato Fukuda, Kohei Ishimura, Yuto Murakami, Ryuta Muromoto, Koichi Fujiwara, Mizuki Watanabe
Publikováno v:
ACS Med Chem Lett
[Image: see text] Resolvins (Rvs) are highly potent anti-inflammatory lipid mediators that are chemically and biologically unstable because of their polyunsaturated structures. To address this issue, we designed benzene congeners of RvE2, i.e., o-, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83dfa44f444142286ef3e2776be54b9f
https://pubmed.ncbi.nlm.nih.gov/32292553
https://pubmed.ncbi.nlm.nih.gov/32292553
Autor:
Kohei Ishimura, Katsuyuki Kaneda, Masabumi Minami, Satoshi Deyama, Shun Aoki, Satoshi Shuto, Hayato Fukuda
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 93:2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5ff9740af1eb3285896a93b7832f636
https://doi.org/10.1254/jpssuppl.93.0_2-p-178
https://doi.org/10.1254/jpssuppl.93.0_2-p-178
Autor:
Kento Shimoda, Soichiro Ide, Hiroe Suzuki, Natsuko Hitora-Imamura, Yuka Ishikawa, Masamichi Satoh, Hayato Fukuda, Satoshi Shuto, Kohei Ishimura, Katsuyuki Kaneda, Masabumi Minami, Satoshi Deyama
Publikováno v:
Psychopharmacology. 235(1)
Resolvins are bioactive lipid mediators that are generated from docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). We recently demonstrated that the DHA-derived resolvins D1 and D2 exert antidepressant effects. However, whether the EPA-deriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2ece731859ece30679c209a9752fcac
https://pubmed.ncbi.nlm.nih.gov/29090333
https://pubmed.ncbi.nlm.nih.gov/29090333
Autor:
Hiroshi Abe, Satoshi Shuto, Kotaro Matsubara, Mitsuhiro Arisawa, Makoto Tanabe, Koki Hirashima, Tadashi Matsuda, Yuuki Takakura, Hayato Fukuda, Daichi Fushihara, Kohei Ishimura, Ryuta Muromoto, Toru Hirao, Ryutaro Kanada
Publikováno v:
Organic letters. 18(24)
Lipid chemical mediator resolvins with highly potent anti-inflammatory activity can be leads to develop novel anti-inflammatory drugs; however, they are unstable in oxygen due to their characteristic polyunsaturated structures. To solve the problem,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f713508e0e0b17a6bc9858263c0afd7
https://pubmed.ncbi.nlm.nih.gov/27978690
https://pubmed.ncbi.nlm.nih.gov/27978690
Autor:
Hayato Fukuda, Ryuta Muromoto, Yuuki Takakura, Kohei Ishimura, Ryutaro Kanada, Daichi Fushihara, Makoto Tanabe, Kotaro Matsubara, Toru Hirao, Koki Hirashima, Hiroshi Abe, Mitsuhiro Arisawa, Tadashi Matsuda, Satoshi Shuto
Publikováno v:
Organic Letters; Dec2016, Vol. 18 Issue 24, p6224-6227, 4p