Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kohei Ihara"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Parkinson’s disease (PD) is the second most common neurodegenerative disease, and diagnostic methods and biomarkers for patients without subjective motor symptoms have not yet been established. Previously, we developed a cytochrome P450 in
Externí odkaz:
https://doaj.org/article/9a9a916fdeae46899dfd268c004a39af
Autor:
Jun Xu, Shuichi Nakamura, Md Shafiqul Islam, Yijie Guo, Kohei Ihara, Rintaro Tomioka, Mizuki Masuda, Hiroshi Yoneyama, Emiko Isogai
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0154165 (2016)
Mannose-binding lectin (MBL) is a key pattern recognition molecule in the lectin pathway of the complement system, an important component of innate immunity. MBL functions as an opsonin which enhances the sequential immune process such as phagocytosi
Externí odkaz:
https://doaj.org/article/fbf7020ec5d046dabb6fa3226555f7b5
Publikováno v:
Microbiology. 168
AlaE is the smallest amino acid exporter identified in Escherichia coli . It exports l-alanine using the proton motive force and plays a pivotal role in maintaining intracellular l-alanine homeostasis by acting as a safety valve. However, our underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::396f833f2923d767cf284a17d7b4e577
https://doi.org/10.1099/mic.0.001147
https://doi.org/10.1099/mic.0.001147
Publikováno v:
Drug Metabolism and Pharmacokinetics. 47:100472
To overcome bladder cancer, one of the most common cancer and deadly cancers in the world, early diagnosis and treatment interventions are crucial. The development of efficient diagnostic methods is required. Previously, we developed a cytochrome P45
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f232286939aa38c056321c9a6ec85d
https://doi.org/10.1016/j.dmpk.2022.100472
https://doi.org/10.1016/j.dmpk.2022.100472
Autor:
Emiko Isogai, Shuji Shigenobu, Kohei Ihara, Yumiko Makino, Hiroshi Yoneyama, Hatsuhiro Hori, Tasuke Ando, Kazuki Sato
Publikováno v:
Journal of Bioscience and Bioengineering. 123:444-450
The alaE gene in Escherichia coli encodes an l -alanine exporter that catalyzes the active export of l -alanine using proton electrochemical potential. In our previous study, alaE expression was shown to increase in the presence of l -alanyl- l -alan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f44c02f000bdfd9e4d34827e285a8420
https://doi.org/10.1016/j.jbiosc.2016.11.015
https://doi.org/10.1016/j.jbiosc.2016.11.015
Autor:
Rie Suzuki, Hiroshi Isogai, Emiko Isogai, Hiroshi Yoneyama, Yukako Koyanagi, Kohei Ihara, Hikaru Miyagi
Publikováno v:
Pathogens and disease. 77(4)
Susceptibility to enterohemorrhagic Escherichia coli (EHEC) infection varies among humans. The intestinal microbiota seems to play an essential role in host defense against EHEC; thus, we hypothesized that indigenous bacteria, such as Clostridium ram
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3d24d12b4b6b63b43a8ebe19379386a
https://pubmed.ncbi.nlm.nih.gov/31344225
https://pubmed.ncbi.nlm.nih.gov/31344225
Publikováno v:
Archives of Microbiology. 199:105-114
The Escherichia coli alaE gene encodes the l-alanine exporter, AlaE, that catalyzes active export of l-alanine using proton electrochemical potential. The transporter comprises only 149 amino acid residues and four predicted transmembrane domains (TM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4a4db38519adb4db478a3c6bac7587c
https://doi.org/10.1007/s00203-016-1279-4
https://doi.org/10.1007/s00203-016-1279-4
Autor:
Emiko Isogai, Xu Jun, Md. Shafiqul Islam, Mizuki Masuda, Hiroshi Yoneyama, Kohei Ihara, Rintaro Tomioka, Yijie Guo, Shuichi Nakamura
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 4, p e0154165 (2016)
PLoS ONE, Vol 11, Iss 4, p e0154165 (2016)
Mannose-binding lectin (MBL) is a key pattern recognition molecule in the lectin pathway of the complement system, an important component of innate immunity. MBL functions as an opsonin which enhances the sequential immune process such as phagocytosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad5a9ecca24c6314274b278c6f4d7e07
http://europepmc.org/articles/PMC4841586
http://europepmc.org/articles/PMC4841586
Autor:
Kohei Ihara, Michiya Kume, Miyuki Sumitomo, Shuichi Tada, Hideaki Yoshiwara, Tomimoto Takahiro, Muneo Yamamoto
Publikováno v:
Journal of the Japan Institute of Metals. 76:107-111
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7996647c37bbd3694eab2b3f7e32d035
https://doi.org/10.2320/jinstmet.76.107
https://doi.org/10.2320/jinstmet.76.107
Autor:
Emiko Isogai, Satoshi Katsube, Seryoung Kim, Tasuke Ando, Hiroshi Yoneyama, Hatsuhiro Hori, Kohei Ihara
Publikováno v:
MicrobiologyOpen
We previously reported that the alaE gene of Escherichia coli encodes the l-alanine exporter AlaE. The objective of this study was to elucidate the mechanism of the AlaE exporter. The minimum inhibitory concentration of l-alanine and l-alanyl-l-alani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf8a7e40cd8849f891475e37f397c6eb
https://pubmed.ncbi.nlm.nih.gov/26073055
https://pubmed.ncbi.nlm.nih.gov/26073055