Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Kohei Hosokawa"'
Autor:
Hiroki Mizumaki, Dung Cao Tran, Kohei Hosokawa, Kazuyoshi Hosomichi, Yoshitaka Zaimoku, Hiroyuki Takamatsu, Hirohito Yamazaki, Ken Ishiyama, Rena Yamazaki, Hiroshi Fujiwara, Atsushi Tajima, Shinji Nakao
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-5 (2023)
Externí odkaz:
https://doaj.org/article/bfc30ef69375475eaaebde07df5ae121
Autor:
Ken Ishiyama, Tran Cao Dung, Tatsuya Imi, Kohei Hosokawa, Yasuhito Nannya, Hirohito Yamazaki, Seishi Ogawa, Shinji Nakao
Publikováno v:
eJHaem, Vol 3, Iss 4, Pp 1116-1125 (2022)
Abstract To determine the significance of increased Wilms tumor 1 (WT1) gene expression in the peripheral blood of patients with acquired aplastic anemia (AA), we analyzed serial changes in WT1 mRNA copy number (WT1cn) in 63 patients with AA as well
Externí odkaz:
https://doaj.org/article/a915a945bd9145b8a3dae8ec5dec4271
Autor:
Takamasa Katagiri, Jorge Luis Espinoza, Mizuho Uemori, Honoka Ikeda, Kohei Hosokawa, Ken Ishiyama, Takeshi Yoroidaka, Tatsuya Imi, Hiroyuki Takamatsu, Tatsuhiko Ozawa, Hiroyuki Kishi, Yasuhiko Yamamoto, Mahmoud Ibrahim Elbadry, Yoshinori Yoshida, Kazuhisa Chonabayashi, Katsuto Takenaka, Koichi Akashi, Yasuhito Nannya, Seishi Ogawa, Shinji Nakao
Publikováno v:
eJHaem, Vol 3, Iss 3, Pp 669-680 (2022)
Abstract The phenotypic changes in hematopoietic stem progenitor cells (HSPCs) with somatic mutations of malignancy‐related genes in patients with acquired aplastic anemia (AA) are poorly understood. As our initial study showed increased CXCR4 expr
Externí odkaz:
https://doaj.org/article/d29be8cd58114bf5b769d39c97fb15bd
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract CD81 is an integral membrane protein of the tetraspanin family and forms complexes with a variety of other cell surface membrane proteins. CD81 is involved in cell migration and B cell activation. However, the mechanism of the transcriptiona
Externí odkaz:
https://doaj.org/article/faa70a72fbc64dc280a66910b587ae60
Autor:
Ken Ishiyama, Keijiro Sato, Tatsuya Imi, Kohei Hosokawa, Yukio Kondo, Naomi Sugimori, Hirohito Yamazaki, Shinji Nakao
Publikováno v:
eJHaem, Vol 1, Iss 1, Pp 243-248 (2020)
Abstract To identify factors affecting responsiveness to eltrombopag (EPAG), we retrospectively analyzed 38 aplastic anemia patients treated with EPAG who were refractory (n = 29) or showed an inadequate response (n = 9) to conventional therapies. Th
Externí odkaz:
https://doaj.org/article/21264fb7ea7a49a2a41153669908a303
Autor:
Hiroyuki Takamatsu, MD, PhD, Shinya Yamada, MD, Noriaki Tsuji, MD, Noriharu Nakagawa, MD, Erika Matsuura, MD, Atsuo Kasada, MD, PhD, Keijiro Sato, MD, Kohei Hosokawa, MD, PhD, Noriko Iwaki, MD, PhD, Masahisa Arahata, MD, Hidenori Tanaka, BS, Shinji Nakao, MD, PhD
Publikováno v:
Transplantation Direct, Vol 7, Iss 6, p e697 (2021)
Background. IVIG is occasionally used for preventing and treating severe infections of patients who are to undergo transplantation. Administration of IVIG, which includes high-titer antibodies (Abs) against HLA class I and II, might have a substantia
Externí odkaz:
https://doaj.org/article/f4eb3d98f7f34a42bc8b78f97c0bcd55
Autor:
Hiroki Mizumaki, Kazuyoshi Hosomichi, Kohei Hosokawa, Takeshi Yoroidaka, Tatsuya Imi, Yoshitaka Zaimoku, Takamasa Katagiri, Mai Anh Thi Nguyen, Dung Cao Tran, Mahmoud Ibrahim Yousef Elbadry, Kazuhisa Chonabayashi, Yoshinori Yoshida, Hiroyuki Takamatsu, Tatsuhiko Ozawa, Fumihiro Azuma, Hiroyuki Kishi, Yoichi Fujii, Seishi Ogawa, Atsushi Tajima, Shinji Nakao
Publikováno v:
Haematologica, Vol 106, Iss 6 (2020)
Leukocytes that lack HLA allelic expression are frequently detected in patients with acquired aplastic anemia (AA) who respond to immunosuppressive therapy (IST), although the exact mechanisms underlying the HLA loss and HLA allele repertoire likely
Externí odkaz:
https://doaj.org/article/915ada09b34f45d5800c24f9a352ebba
Autor:
Mahmoud I. Elbadry, Hiroki Mizumaki, Kohei Hosokawa, J. Luis Espinoza, Noriharu Nakagawa, Kazuhisa Chonabayashi, Yoshinori Yoshida, Takamasa Katagiri, Kazuyoshi Hosomichi, Yoshitaka Zaimoku, Tatsuya Imi, Mai Anh Thi Nguyen, Youichi Fujii, Atsushi Tajima, Seishi Ogawa, Katsuto Takenaka, Koichi Akashi, Shinji Nakao
Publikováno v:
Haematologica, Vol 104, Iss 10 (2019)
Externí odkaz:
https://doaj.org/article/1be58986e73a4ae9ab9202a1c2542199
Autor:
Sachiko Kiyoto, Yoshifumi Sugawara, Kohei Hosokawa, Rieko Nishimura, Natsumi Yamashita, Shozo Ohsumi, Teruhito Mochizuki
Publikováno v:
Asia Oceania Journal of Nuclear Medicine and Biology, Vol 4, Iss 1, Pp 3-11 (2016)
Objective The mortality of patients with locally advanced triple-negative breast cancer (TNBC) is high, and pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) is associated with improved prognosis. This retrospective study was des
Externí odkaz:
https://doaj.org/article/22ee664411e14669b42b788a9c416ece
Autor:
Kohei Hosokawa, Sachiko Kajigaya, Xingmin Feng, Marie J. Desierto, Maria del Pilar Fernandez Ibanez, Olga Rios, Barbara Weinstein, Phillip Scheinberg, Danielle M. Townsley, Neal S. Young
Publikováno v:
Haematologica, Vol 102, Iss 1 (2017)
Aplastic anemia is an acquired bone marrow failure characterized by marrow hypoplasia, a paucity of hematopoietic stem and progenitor cells, and pancytopenia of the peripheral blood, due to immune attack on the bone marrow. In aplastic anemia, a majo
Externí odkaz:
https://doaj.org/article/793e53c3a82b46609f93744072bbc31c