Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Kohei Arasaki"'
Autor:
Takemasa Nakamura, Takashi Shimizu, Naho Nishinakama, Reika Takahashi, Kohei Arasaki, Akihiko Uda, Kenta Watanabe, Masahisa Watarai
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Francisella tularensis, the causative agent of tularemia, is a facultative intracellular bacterium. Although the life cycle of this bacterium inside phagocytic cells (e.g., macrophages, neutrophils) has been well analyzed, the dif
Externí odkaz:
https://doaj.org/article/083329645f4d420786f1afc280220473
Publikováno v:
eLife, Vol 12 (2024)
Rab GTPases are representative targets of manipulation by intracellular bacterial pathogens for hijacking membrane trafficking. Legionella pneumophila recruits many Rab GTPases to its vacuole and exploits their activities. Here, we found that infecti
Externí odkaz:
https://doaj.org/article/dc58dac948a14e369dbf50d4b75fb61b
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100410- (2021)
Summary: The intracellular bacterial pathogen Legionella pneumophila exploits host cellular systems using approximately 300 effector proteins to establish a replicative niche known as the Legionella-containing vacuole (LCV). During infection, both ho
Externí odkaz:
https://doaj.org/article/d8b9d454f33348c38a647f1d4971bbcc
Autor:
Mio Kawabata, Honoka Matsuo, Takumi Koito, Misaki Murata, Tomoko Kubori, Hiroki Nagai, Mitsuo Tagaya, Kohei Arasaki
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009437 (2021)
Legionella pneumophila (L. pneumophila) is a gram-negative bacterium that replicates in a compartment that resembles the host endoplasmic reticulum (ER). To create its replicative niche, L. pneumophila manipulates host membrane traffic and fusion mac
Externí odkaz:
https://doaj.org/article/72f509a5abc347a190a2ae86bd3551ff
Autor:
Hana Kimura, Kohei Arasaki, Yuki Ohsaki, Toyoshi Fujimoto, Takayuki Ohtomo, Junji Yamada, Mitsuo Tagaya
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 5, Pp 805-819 (2018)
Lipid droplets (LDs) are ubiquitous organelles that contain neutral lipids and are surrounded by a phospholipid monolayer. How proteins specifically localize to the phospholipid monolayer of the LD surface has been a matter of extensive investigation
Externí odkaz:
https://doaj.org/article/03763c1cc20747108800b312df551246
Legionella effector Lpg1137 shuts down ER-mitochondria communication through cleavage of syntaxin 17
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
The pathogenic bacteriumLegionella pneumophila replicates within macrophages. Here, the authors show that L. pneumophilasecretes an effector protein that cleaves the host protein syntaxin 17, thus inhibiting autophagy and staurosporine-induced apopto
Externí odkaz:
https://doaj.org/article/ec754c6774e2435dac51a43ad70686a2
Publikováno v:
Contact, Vol 2 (2019)
During lipid droplet (LD) formation, several key enzymes for neutral lipid biosynthesis, such as acyl-CoA synthetase 3 (ACSL3), translocate from the bilayer of the endoplasmic reticulum membrane or mitochondria-associated membrane to the monolayer su
Externí odkaz:
https://doaj.org/article/fe1a96c6d72e44ac8cdef1e1367e4f80
Autor:
Andree Hubber, Kohei Arasaki, Fubito Nakatsu, Camille Hardiman, David Lambright, Pietro De Camilli, Hiroki Nagai, Craig R Roy
Publikováno v:
PLoS Pathogens, Vol 10, Iss 7, p e1004222 (2014)
The Dot/Icm system of the intracellular pathogen Legionella pneumophila has the capacity to deliver over 270 effector proteins into host cells during infection. Important questions remain as to spatial and temporal mechanisms used to regulate such a
Externí odkaz:
https://doaj.org/article/264807b31ba5482dad5d8d46ec4484f5
Autor:
Misaki Murata, Riku Kanamori, Tomoe Kitao, Tomoko Kubori, Hiroki Nagai, Mitsuo Tagaya, Kohei Arasaki
Publikováno v:
Journal of cell science. 135(6)
The gram-negative bacterium, Legionella pneumophila is known to manipulate the host cellular functions. L. pneumophila secretes bacterial proteins called Legionella effectors into the host cytosol that are necessary for these manipulations. The Legio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd0a75d3f266fc8eca34559d41ec7cf
https://pubmed.ncbi.nlm.nih.gov/35224642
https://pubmed.ncbi.nlm.nih.gov/35224642
Autor:
Hiroki Inoue, Kaito Hayashi, Mitsuo Tagaya, Jessica Angulo-Capel, Hidetoshi Kumata, Yuichi Wakana, Masato Taoka, Felix Campelo, Tomonari Umemura, Takumi Nemoto, Chiaki Watanabe, Kohei Arasaki, Maria F. Garcia-Parajo
Publikováno v:
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
The Journal of Cell Biology
Universitat Politècnica de Catalunya (UPC)
The Journal of Cell Biology
Wakana et al. describe a new role for SCAP, a key regulatory protein in cholesterol metabolism, in promoting Golgi PI4P turnover and the biogenesis of the TGN-derived transport carriers CARTS via interaction with the cholesterol/PI4P exchange machine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf3e1139e167ce454cd94e386159f5b
