Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Koh-ichi Seki"'
Autor:
Hiromichi Akizawa, Mikiko Kudo, Koh-ichi Seki, Tetsuya Ishihara, Nobuhiro Oshima, Kazue Ohkura
Publikováno v:
Heterocycles. 84(2):1057-1065
Direct UV-irradiation of 5-fluoro-1,3-dimethyluracil (5-FDMU) and naphthalene (1) with a 500 W high-pressure mercury lamp in a degassed Pyrex tube (λ > 300 nm) predominantly afforded benzopyrimidobarrelene derivative (2) through 1,4-addition, while
Autor:
Yuji Kuge, Yoichi Noya, Yusuke Mikami, Akira K. Suzuki, Koh-ichi Seki, Kazue Ohkura, Shinji Taneda
Publikováno v:
Environmental Science and Pollution Research. 17(3):717-723
Goal, Scope, and Background: We recently developed a new isolation method for diesel exhaust particles (DEP), involving successive extraction with H2O, sodium bicarbonate, and sodium hydroxide, in which the sodium hydroxide extract was found to consi
Autor:
Nagara Tamaki, Koh ichi Seki, Yumiko Katada, Naoyuki Obokata, Hideo Saji, Yuji Kuge, Hiroyuki Kimura, Kazuki Aita, Yukihiko Sugimoto, Takashi Temma
Publikováno v:
Nuclear Medicine and Biology. 36:869-876
Introduction Despite extensive attempts to develop cyclooxygenase (COX)-2 imaging radiotracers, no suitable positron emission tomography (PET)/single photon emission computed tomography (SPECT) tracers are currently available for in vivo imaging of C
Publikováno v:
Journal of Fluorescence. 20:225-234
Fluorescent analysis has been widely used in biological, chemical and analytical research. A useful fluorescent labeling agent should include NIR emission, a large Stoke's shift, and good labeling ability without interfering with the pharmacological
Autor:
Songji Zhao, Masayuki Takahashi, Koh-ichi Seki, Ken-ichi Nishijima, Yuji Kuge, Nagara Tamaki, Kazue Ohkura
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 51:384-387
The expression of thymidine phosphorylase (TP) is strongly associated with angiogenesis in tumors and activation of antitumor agents. We designed a novel 5-125I-labeled 6-(2-iminoimidazolidinyl)methyluracil hydrochloride ([125I]5I6IMU-HCl) to develop
Autor:
Takashi Temma, Toshiyuki Takahashi, Hidekazu Kawashima, Nagara Tamaki, Toshiki Takei, Yuji Kuge, Songji Zhao, Koh-ichi Seki, Masashi Kohanawa, Yan Zhao
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 34:2096-2105
Increased (18)F-fluorodeoxyglucose (FDG) uptake in inflammatory lesions, particularly in granulomatous inflammation (e.g., sarcoidosis), makes it difficult to differentiate malignant tumors from benign lesions and is the main source of false-positive
Publikováno v:
Photochemistry and Photobiology. 74:385-390
Photolysis of 6-chloro-1,3-dimethyluracil and mesitylene in the presence of trifluoroacetic acid (TFA) at low temperature gave 1,3,5,7,9- and 1,3,6,8,10-pentamethylcyclooctapyrimidine-2,4-diones (1b, 1c). Sequential photoreaction of the former (1b) r
Autor:
Ken-ichi Nishijima, Yuji Kuge, Noriko Motoki, Koichi Morita, Koh-ichi Seki, Nagara Tamaki, Kazue Ohkura
Publikováno v:
International Congress Series. 1264:261-266
Background: S-(−)[11C]CGP-12177 is reported to be a useful PET ligand for β-adrenoreceptor in the heart and lung. Its pharmacokinetic properties, however, have not been fully examined due to difficulty in S-(−)[11C]CGP-12177 production. Recently
Autor:
Kazue Ohkura, Chiaki Yokota, Nagara Tamaki, Kenji Hikosaka, Kazuo Minematsu, Yuji Kuge, Koh-ichi Seki, T. Shiga, Tomohito Kaji
Publikováno v:
International Congress Series. 1264:44-52
Objectives: Brain distributions of [123I]iomazenil ([123I]IMZ) and [1-14C]octanoate were compared with CBF and histopathologic findings in a rat model of focal cerebral ischemia, in order to characterize [123I]IMZ and [1-11C]octanoate as markers of n
Autor:
Kouya Yamaki, Shinji Taneda, Akiyo Sakushima, Hideyuki Hayashi, Masakatsu Sakata, Akira K. Suzuki, Kazuyuki Kamata, Noriko Toda, Shin Yoshino, Koh-ichi Seki, Yoki Mori
Publikováno v:
Journal of Health Science. 50:133-141
Vasodilatory compounds in the weak acidic fraction of a benzene extract of diesel exhaust particles (DEP) were fractionated by column chromatography through silica gel, and the chemical structures of these compounds were analyzed using GC-MS and 1H-N