Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Koh-ichi Nakashiro"'
Autor:
Hiroyuki Goda, Koh-ichi Nakashiro, Yoshifumi Sano, Tomoko Adachi, Norihiko Tokuzen, Nobuyuki Kuribayashi, Satoshi Hino, Daisuke Uchida
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Oral squamous cell carcinomas unusually show distant metastasis to the lung after primary treatment, which can be difficult to differentiate from primary squamous cell carcinoma of the lung. While the location and number of tumor nodules is
Externí odkaz:
https://doaj.org/article/5a76096cd5a44ef8a9560c223f9bc681
Publikováno v:
Cancers, Vol 16, Iss 8, p 1492 (2024)
No clinically useful predictors of latent cervical lymph node metastasis (LNM) in early oral squamous cell carcinoma (OSCC) are available. In this study, we focused on the microRNAs (miRNAs) involved in the expression of numerous genes and explored t
Externí odkaz:
https://doaj.org/article/a0869bcbea8044cc988d25d0b6bb390f
Autor:
Toshiki Hyodo, Nobuyuki Kuribayashi, Chonji Fukumoto, Yuske Komiyama, Ryo Shiraishi, Ryouta Kamimura, Yuta Sawatani, Erika Yaguchi, Tomonori Hasegawa, Sayaka Izumi, Takahiro Wakui, Koh-ichi Nakashiro, Daisuke Uchida, Hitoshi Kawamata
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Mutations in p53 are common in human oral squamous cell carcinoma (OSCC). However, in previous analyses, only detection of mutant p53 protein using immunohistochemistry or mutations in some exons have been examined. Full length mutant p53 pr
Externí odkaz:
https://doaj.org/article/c3273cc919d246c78c8e65a976e85db2
Autor:
Koh-ichi Nakashiro, Norihiko Tokuzen, Masato Saika, Hiroyuki Shirai, Nobuyuki Kuribayashi, Hiroyuki Goda, Daisuke Uchida
Publikováno v:
Cancers, Vol 15, Iss 16, p 4138 (2023)
Recently, numerous tumor-suppressive microRNAs (TS-miRs) have been identified in human malignancies. Here, we attempted to identify novel TS-miRs in oral squamous cell carcinoma (OSCC). First, we transfected human OSCC cells individually with 968 syn
Externí odkaz:
https://doaj.org/article/c90f3aa51e124749b7407662a6235507
Autor:
Yuta Sawatani, Yuske Komiyama, Koh-ichi Nakashiro, Daisuke Uchida, Chonji Fukumoto, Michiko Shimura, Tomonori Hasegawa, Ryouta Kamimura, Masayo Hitomi-Koide, Toshiki Hyodo, Hitoshi Kawamata
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 17, p 6292 (2020)
Administration of cetuximab (C-mab) in combination with paclitaxel (PTX) has been used for patients with head and neck squamous cell carcinoma (SCC) clinically. In this study, we attempted to clarify the molecular mechanisms of the enhancing anticanc
Externí odkaz:
https://doaj.org/article/9aa895be0ca04626be704e3e5eba7e04
Autor:
Tomoyuki Tano, Masato Okamoto, Shin Kan, Takashi Bando, Hiroyuki Goda, Koh-ichi Nakashiro, Shigetaka Shimodaira, Shigeo Koido, Sadamu Homma, Tomonobu Fujita, Mitsunobu Sato, Naomi Yamashita, Hiroyuki Hamakawa, Yutaka Kawakami
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 7, Pp 805-814 (2013)
Eighty-one patients with oral squamous cell carcinoma (OSCC) received oral fluoropyrimidine UFT and radiotherapy (RT) with or without an immunotherapeutic agent OK-432. Both overall survival and progression-free survival of patients who received RT +
Externí odkaz:
https://doaj.org/article/efe684aff10c4d12998e550e56468b38
Autor:
Tomoyuki Tano, Masato Okamoto, Shin Kan, Koh-ichi Nakashiro, Shigetaka Shimodaira, Shigeo Koido, Sadamu Homma, Mitsunobu Sato, Tomonobu Fujita, Yutaka Kawakami, Hiroyuki Hamakawa
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 3, Pp 305-314 (2013)
Antitumor functions of the host immune system are frequently compromised in patients with malignancies. In the current study, we evaluated the relationship between expression ratio of mRNAs for the antiapoptotic protein Bcl-2 and the proapoptotic pro
Externí odkaz:
https://doaj.org/article/6a023611737a4da1bf4a6fa896a0d81b
Autor:
Yohei Fujita, Masato Okamoto, Hiroyuki Goda, Tomoyuki Tano, Koh-ichi Nakashiro, Atsuro Sugita, Tomonobu Fujita, Shigeo Koido, Sadamu Homma, Yutaka Kawakami, Hiroyuki Hamakawa
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e110378 (2014)
PURPOSE:We investigated whether serum interleukin (IL)-8 reflects the tumor microenvironment and has prognostic value in patients with oral squamous cell carcinoma (OSCC). EXPERIMENTAL DESIGN:Fifty OSCC patients who received radical resection of thei
Externí odkaz:
https://doaj.org/article/0a42b66796984c7087cb7743fa06d5dc
Autor:
Fumiaki Shikata, Tomohisa Sakaue, Koh-ichi Nakashiro, Mikio Okazaki, Mie Kurata, Toru Okamura, Masahiro Okura, Masahiro Ryugo, Yuki Nakamura, Takumi Yasugi, Shigeki Higashiyama, Hironori Izutani
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94550 (2014)
BACKGROUND: Liver dysfunction and cirrhosis affect vasculature in several organ systems and cause impairment of organ functions, thereby increasing morbidity and mortality. Establishment of a mouse model of hepatopulmonary syndrome (HPS) would provid
Externí odkaz:
https://doaj.org/article/3bad7cee91e949778073c5d0ced219b9
Autor:
Hiroyuki Goda, Koh-ichi Nakashiro, Yoshifumi Sano, Tomoko Adachi, Norihiko Tokuzen, Nobuyuki Kuribayashi, Satoshi Hino, Daisuke Uchida
Oral squamous cell carcinomas unusually show distant metastasis to the lung after primary treatment, which can be difficult to differentiate from primary squamous cell carcinoma of the lung. While the location and number of tumor nodules is helpful i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3751f4f0d0a54ad3aaf234381cb57f22
https://doi.org/10.21203/rs.3.rs-2745240/v1
https://doi.org/10.21203/rs.3.rs-2745240/v1