Zobrazeno 1 - 10
of 228
pro vyhledávání: '"Koh Takeuchi"'
Autor:
Yutaka Takeda, Takumi Chinen, Shunnosuke Honda, Sho Takatori, Shotaro Okuda, Shohei Yamamoto, Masamitsu Fukuyama, Koh Takeuchi, Taisuke Tomita, Shoji Hata, Daiju Kitagawa
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The triplet microtubule, a core structure of centrioles crucial for the organization of centrosomes, cilia, and flagella, consists of unclosed incomplete microtubules. The mechanisms of its assembly represent a fundamental open question in b
Externí odkaz:
https://doaj.org/article/572670d23eae45859fc7bba1773e7c4c
Autor:
Jun-ichi Sugiyama, Yuji Tokunaga, Mafumi Hishida, Masahito Tanaka, Koh Takeuchi, Daisuke Satoh, Masahiko Imashimizu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract The collective intermolecular dynamics of protein and water molecules, which overlap in the sub-terahertz (THz) frequency region, are relevant for expressing protein functions but remain largely unknown. This study used dielectric relaxation
Externí odkaz:
https://doaj.org/article/dea714d965cb42e2bb6ac4ba512cc46a
Autor:
Yuki Hosono, Satoshi Uchida, Moe Shinkai, Chad E. Townsend, Colin N. Kelly, Matthew R. Naylor, Hsiau-Wei Lee, Kayoko Kanamitsu, Mayumi Ishii, Ryosuke Ueki, Takumi Ueda, Koh Takeuchi, Masatake Sugita, Yutaka Akiyama, Scott R. Lokey, Jumpei Morimoto, Shinsuke Sando
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Naturally occurring peptides with high membrane permeability often have backbone ester bonds. Here, the authors investigated the effect of an amide-to-ester substitution on membrane permeability of peptides and found the substitution is useful for im
Externí odkaz:
https://doaj.org/article/a59489e908164722a8c86ea5023eb75f
Autor:
Maina Sogabe, Kaoru Ishikawa, Toshihiro Takamatsu, Koh Takeuchi, Takahiro Kanno, Koji Fujimoto, Tetsuro Miyazaki, Toshihiro Kawase, Toshihiko Sato, Kenji Kawashima
Publikováno v:
Array, Vol 19, Iss , Pp 100308- (2023)
In thoraco-laparoscopic surgery, the identification of a bleeding source is recognized as one of the most important issues with hemostasis during operation. However, previously proposed techniques are only capable of detecting an approximate bleeding
Externí odkaz:
https://doaj.org/article/b73d693eeea14d8fa8088fb080ff0528
Autor:
Kaiku Uegaki, Yuji Tokunaga, Michio Inoue, Seiji Takashima, Kenji Inaba, Koh Takeuchi, Ryo Ushioda, Kazuhiro Nagata
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112742- (2023)
Summary: The endoplasmic reticulum (ER) maintains an oxidative redox environment that is advantageous for the oxidative folding of nascent polypeptides entering the ER. Reductive reactions within the ER are also crucial for maintaining ER homeostasis
Externí odkaz:
https://doaj.org/article/c8656a4d782e41afb0fd6a0599406302
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Recently, research has been conducted to automatically control anesthesia using machine learning, with the aim of alleviating the shortage of anesthesiologists. In this study, we address the problem of predicting decisions made by anesthesio
Externí odkaz:
https://doaj.org/article/525999869a00479a86236eba3a2322dc
Autor:
Natsuki Osaka, Yoshihisa Hirota, Doshun Ito, Yoshiki Ikeda, Ryo Kamata, Yuki Fujii, Venkat R. Chirasani, Sharon L. Campbell, Koh Takeuchi, Toshiya Senda, Atsuo T. Sasaki
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
RAS is a founding member of the RAS superfamily of GTPases. These small 21 kDa proteins function as molecular switches to initialize signaling cascades involved in various cellular processes, including gene expression, cell growth, and differentiatio
Externí odkaz:
https://doaj.org/article/e134222d79f147a6ad0f9399f17a1234
Autor:
Rebecca Freilich, Miguel Betegon, Eric Tse, Sue-Ann Mok, Olivier Julien, David A. Agard, Daniel R. Southworth, Koh Takeuchi, Jason E. Gestwicki
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Small heat shock proteins (sHSPs) limit the aggregation of proteins, such as tau. Here the authors show that Hsp27 recognizes two aggregation-prone regions of tau and that this interaction competes with Hsp27 oligomerization.
Externí odkaz:
https://doaj.org/article/ea828c6ee26840cd8de08621cb5f0b7d
Autor:
Scott A. Robson, Koh Takeuchi, Andras Boeszoermenyi, Paul W. Coote, Abhinav Dubey, Sven Hyberts, Gerhard Wagner, Haribabu Arthanari
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Structure determination of large proteins by solution state NMR is challenging due to spectral overlap. Here the authors present a labeling strategy using 2-13C and 3-13C pyruvate as carbon source for E. coli, which increases the effective resolution
Externí odkaz:
https://doaj.org/article/e5ddb6cd608240a3921746ce12e443cd
Publikováno v:
Annals of Pediatric Cardiology, Vol 12, Iss 1, Pp 66-68 (2019)
Aortic arch obstruction and bronchial compression are possible postoperative complications in patients with truncus arteriosus communis (TAC) with interrupted aortic arch (IAA). We present a case of bronchial compression as adverse effect of right pu
Externí odkaz:
https://doaj.org/article/57ea0ac5f49443e19f157a4c567b550d