Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Koh Miura"'
Autor:
Yuko Minami, Seiki Kanemura, Jun Kusaka, Makoto Kinouchi, Shinichi Suzuki, Hajime Iwasashi, Yoshikazu Nishino, Yoichiro Kakugawa, Koh Miura
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract It has been postulated that being breastfed in infancy affects not only health status in childhood but also disease risk in adulthood. To investigate the association of being breastfed with the risks of adult colorectal cancer and benign tum
Externí odkaz:
https://doaj.org/article/c7423326f6d94d78978eaec34c80997d
Autor:
Kazuhiro Kishimoto, Kosuke Kanazawa, Miyuki Nomura, Takuji Tanaka, Taeko Shigemoto‐Kuroda, Katsuya Fukui, Koh Miura, Koreyuki Kurosawa, Masaaki Kawai, Hiroyuki Kato, Keiko Terasaki, Yoshimi Sakamoto, Yoji Yamashita, Ikuro Sato, Nobuhiro Tanuma, Keiichi Tamai, Issay Kitabayashi, Kazuto Matsuura, Toshio Watanabe, Jun Yasuda, Hiroyuki Tsuji, Hiroshi Shima
Publikováno v:
Cancer Medicine, Vol 10, Iss 13, Pp 4451-4464 (2021)
Abstract Background Effective treatments for cancer harboring mutant RAS are lacking. In Drosophila, it was reported that PP6 suppresses tumorigenicity of mutant RAS. However, the information how PP6 regulates oncogenic RAS in mammals is limited. Met
Externí odkaz:
https://doaj.org/article/2186d59ebaa343f3b0924baa94f10c5b
Autor:
Keiichi Tamai, Mao Nakamura-Shima, Rie Shibuya-Takahashi, Shin-Ichiro Kanno, Akira Yasui, Mai Mochizuki, Wataru Iwai, Yuta Wakui, Makoto Abue, Kuniharu Yamamoto, Koh Miura, Masamichi Mizuma, Michiaki Unno, Sadafumi Kawamura, Ikuro Sato, Jun Yasuda, Kazunori Yamaguchi, Kazuo Sugamura, Kennichi Satoh
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Abstract Cancer stem cells (CSCs) define a subpopulation of cancer cells that are resistant to therapy. However, little is known of how CSC characteristics are regulated. We previously showed that dormant cancer stem cells are enriched with a CD274lo
Externí odkaz:
https://doaj.org/article/46f507a261a544359c2ee01e6ca995c1
Autor:
Liviu P. Lefter, Makoto Sunamura, Toru Furukawa, Toshimasa Yastsuoka, Hisashi Abe, Hiroko Inoue, Tadayoshi Abe, Shinichi Egawa, Koh Miura, Rina Morita, Akira Horii, Seiki Matsuno
Publikováno v:
Asian Journal of Surgery, Vol 27, Iss 2, Pp 85-92 (2004)
In a previous work, we demonstrated that loss of heterozygosity of 18q is a frequent event significantly associated with poor prognosis in pancreatic cancer. We hypothesized that restoration of heterozygosity of chromosome 18 in pancreatic cancer cel
Externí odkaz:
https://doaj.org/article/4925b0e94e2a4a45b93d0e9eb0285c39
Autor:
Hironobu Sasano, Michiaki Unno, Dean B. Evans, Shinichi Egawa, Takayuki Ii, Kuniharu Yamamoto, Shuji Nagasaki, Yukiko Kamogawa, Junichi Akahira, Yasuhiro Miki, Hiroo Tateno, Kenichi Shiiba, Koh Miura, Yu Katayose, Takashi Suzuki, Ryuichiro Sato
Supplementary Figure 1 from Steroid Sulfatase and Estrogen Sulfotransferase in Colon Carcinoma: Regulators of Intratumoral Estrogen Concentrations and Potent Prognostic Factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef087436f6f3295afb1245fcbd32a19c
https://doi.org/10.1158/0008-5472.22381035.v1
https://doi.org/10.1158/0008-5472.22381035.v1
Autor:
Hironobu Sasano, Michiaki Unno, Dean B. Evans, Shinichi Egawa, Takayuki Ii, Kuniharu Yamamoto, Shuji Nagasaki, Yukiko Kamogawa, Junichi Akahira, Yasuhiro Miki, Hiroo Tateno, Kenichi Shiiba, Koh Miura, Yu Katayose, Takashi Suzuki, Ryuichiro Sato
Supplementary Figure 2 from Steroid Sulfatase and Estrogen Sulfotransferase in Colon Carcinoma: Regulators of Intratumoral Estrogen Concentrations and Potent Prognostic Factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e4335592f087754f81de059dc0dea0
https://doi.org/10.1158/0008-5472.22381029.v1
https://doi.org/10.1158/0008-5472.22381029.v1
Autor:
Hironobu Sasano, Michiaki Unno, Dean B. Evans, Shinichi Egawa, Takayuki Ii, Kuniharu Yamamoto, Shuji Nagasaki, Yukiko Kamogawa, Junichi Akahira, Yasuhiro Miki, Hiroo Tateno, Kenichi Shiiba, Koh Miura, Yu Katayose, Takashi Suzuki, Ryuichiro Sato
Previous epidemiologic and in vitro studies have indicated a potential involvement of estrogens in the pathogenesis of human colon carcinoma, but the precise roles of estrogens have remained largely unknown. Therefore, in this study, we first measure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c86a6677c03107b3d2f7a27a934f19a2
https://doi.org/10.1158/0008-5472.c.6499737.v1
https://doi.org/10.1158/0008-5472.c.6499737.v1
Autor:
Hironobu Sasano, Michiaki Unno, Dean B. Evans, Shinichi Egawa, Takayuki Ii, Kuniharu Yamamoto, Shuji Nagasaki, Yukiko Kamogawa, Junichi Akahira, Yasuhiro Miki, Hiroo Tateno, Kenichi Shiiba, Koh Miura, Yu Katayose, Takashi Suzuki, Ryuichiro Sato
Supplementary Table 1 from Steroid Sulfatase and Estrogen Sulfotransferase in Colon Carcinoma: Regulators of Intratumoral Estrogen Concentrations and Potent Prognostic Factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17168865c12d3144b4ac8f39a28e782c
https://doi.org/10.1158/0008-5472.22381023.v1
https://doi.org/10.1158/0008-5472.22381023.v1
Autor:
Keiko Terasaki, Yoji Yamashita, Kazuto Matsuura, Nobuhiro Tanuma, Kosuke Kanazawa, Hiroyuki Tsuji, Koh Miura, Katsuya Fukui, Hiroshi Shima, Miyuki Nomura, Keiichi Tamai, Ikuro Sato, Takuji Tanaka, Issay Kitabayashi, Koreyuki Kurosawa, Taeko Shigemoto-Kuroda, Kazuhiro Kishimoto, Hiroyuki Kato, Masaaki Kawai, Yoshimi Sakamoto, Toshio Watanabe, Jun Yasuda
Publikováno v:
Cancer Medicine, Vol 10, Iss 13, Pp 4451-4464 (2021)
Cancer Medicine
Cancer Medicine
Background Effective treatments for cancer harboring mutant RAS are lacking. In Drosophila, it was reported that PP6 suppresses tumorigenicity of mutant RAS. However, the information how PP6 regulates oncogenic RAS in mammals is limited. Methods We e
Autor:
Hiroyuki Kato, Yui Inoue, Yoji Yamashita, Takuji Tanaka, Kosuke Kanazawa, Koreyuki Kurosawa, Jun Yasuda, Miyuki Nomura, Kazuhiro Kishimoto, Hiroyuki Tsuji, Hiroshi Shima, Nobuhiro Tanuma, Toshio Watanabe, Koh Miura, Katsuya Fukui, Ikuro Sato
Publikováno v:
Cancer Science
According to TCGA database, mutations in PPP6C (encoding phosphatase PP6) are found in c. 10% of tumors from melanoma patients, in which they coexist with BRAF and NRAS mutations. To assess PP6 function in melanoma carcinogenesis, we generated mice i