Zobrazeno 1 - 10
of 286
pro vyhledávání: '"Koh‐Ichiro Yoshiura"'
Autor:
Daisuke Hatta, Shiho Makiya, Kaito Kanamoto, Kaori Watanabe, Yuki Fuchigami, Shigeru Kawakami, Akira Kinoshita, Koh‐Ichiro Yoshiura, Naohiro Kurotaki, Keiro Shirotani, Nobuhisa Iwata
Publikováno v:
Neuropsychopharmacology Reports, Vol 44, Iss 4, Pp 829-834 (2024)
Abstract Mutations in proline‐rich transmembrane protein 2 (PRRT2) cause paroxysmal kinesigenic dyskinesia (PKD). Recently, we reported that a Prrt2 mutation exacerbated L‐dopa‐induced motor deficits in mice, suggesting that the basal ganglia m
Externí odkaz:
https://doaj.org/article/a06d3827f97847b48d81d98845aa6f20
Autor:
Chisei Satoh, Koh-ichiro Yoshiura, Hiroyuki Mishima, Haruo Yoshida, Haruo Takahashi, Yoshihiko Kumai
Publikováno v:
BMC Medical Genomics, Vol 16, Iss 1, Pp 1-7 (2023)
Abstract Background Chronic inflammation causes bone destruction in middle ear cholesteatomas (MECs). However, the causes of their neoplastic features remain unknown. The present study demonstrated for the first time that neoplastic features of MEC a
Externí odkaz:
https://doaj.org/article/237272bced07417487e069f9dc780f72
Autor:
Tomiko Kuhara, Masahiro Tetsuo, Morimasa Ohse, Toshihiko Shirakawa, Yumiko Nakashima, Koh‐ichiro Yoshiura, Nagaaki Tanaka, Tadashi Taya
Publikováno v:
IJU Case Reports, Vol 6, Iss 6, Pp 436-439 (2023)
Introduction Early diagnosis of patients with urolithiasis or hypouricemia owing to inborn errors of hypoxanthine metabolism is important in preventing renal failure or drug‐induced toxicity. Case presentation We identified three patients with xant
Externí odkaz:
https://doaj.org/article/9ce4f9dd62bd4fea82c51aea37ac409f
Autor:
Yuki Nagata, Ryo Watanabe, Christian Eichhorn, Seiko Ohno, Takeshi Aiba, Taisuke Ishikawa, Yukiko Nakano, Yoshiyasu Aizawa, Kenshi Hayashi, Nobuyuki Murakoshi, Tadashi Nakajima, Nobue Yagihara, Hiroyuki Mishima, Takeaki Sudo, Chihiro Higuchi, Atsushi Takahashi, Akihiro Sekine, Takeru Makiyama, Yoshihiro Tanaka, Atsuyuki Watanabe, Motomi Tachibana, Hiroshi Morita, Koh-Ichiro Yoshiura, Tatsuhiko Tsunoda, Hiroshi Watanabe, Masahiko Kurabayashi, Akihiko Nogami, Yasuki Kihara, Minoru Horie, Wataru Shimizu, Naomasa Makita, Toshihiro Tanaka
Publikováno v:
PLoS ONE, Vol 19, Iss 12, p e0315106 (2024)
[This corrects the article DOI: 10.1371/journal.pone.0277242.].
Externí odkaz:
https://doaj.org/article/54423a06f6ed4aab9f15be37431bda76
Autor:
Nobuo Kanazawa, Hiroaki Hemmi, Noriko Kinjo, Hidenori Ohnishi, Jun Hamazaki, Hiroyuki Mishima, Akira Kinoshita, Tsunehiro Mizushima, Satoru Hamada, Kazuya Hamada, Norio Kawamoto, Saori Kadowaki, Yoshitaka Honda, Kazushi Izawa, Ryuta Nishikomori, Miyuki Tsumura, Yusuke Yamashita, Shinobu Tamura, Takashi Orimo, Toshiya Ozasa, Takashi Kato, Izumi Sasaki, Yuri Fukuda-Ohta, Naoko Wakaki-Nishiyama, Yutaka Inaba, Kayo Kunimoto, Satoshi Okada, Takeshi Taketani, Koichi Nakanishi, Shigeo Murata, Koh-ichiro Yoshiura, Tsuneyasu Kaisho
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Genetic variants of proteasome subunit genes have been shown to associate with perturbed immune function. Here authors show that a heterozygous missense variant of the immunoproteasome subunit β-type 9 causes an autoinflammatory/immune deficiency sy
Externí odkaz:
https://doaj.org/article/bc153bd94dab48289d8e89f5cfa52002
Autor:
Yoshiro Morimoto, Shinji Ono, Shintaro Yoshida, Hiroyuki Mishima, Akira Kinoshita, Takeshi Tanaka, Yoshihiro Komohara, Naohiro Kurotaki, Tatsuya Kishino, Yuji Okazaki, Hiroki Ozawa, Koh-ichiro Yoshiura, Akira Imamura
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Genetic and epidemiological evidence has suggested that genetic factors are important in schizophrenia, although its pathophysiology is poorly understood. This study used whole-exome sequencing to investigate potential novel schizophrenia-ca
Externí odkaz:
https://doaj.org/article/a4ec410821e14154a3dd5e8f9b9d61a8
Autor:
Shuhei Morita, Ken Takeshima, Hiroyuki Ariyasu, Yasushi Furukawa, Shohei Kishimoto, Tomoya Tsuji, Shinsuke Uraki, Hiroyuki Mishima, Akira Kinoshita, Yuichi Takahashi, Hidefumi Inaba, Hiroshi Iwakura, Hiroto Furuta, Masahiro Nishi, Asako Doi, Shin-ichi Murata, Koh-ichiro Yoshiura, Takashi Akamizu
Publikováno v:
BMC Endocrine Disorders, Vol 20, Iss 1, Pp 1-6 (2020)
Abstract Background It is clinically emergent to further understand the pathological mechanism to advance therapeutic strategy for endocrine tumors. A high amount of secretory protein with tumorigenic triggers are thought to induce unfolded protein r
Externí odkaz:
https://doaj.org/article/f0bbbd831d2244148713189a93965599
Autor:
Yuki Nagata, Ryo Watanabe, Christian Eichhorn, Seiko Ohno, Takeshi Aiba, Taisuke Ishikawa, Yukiko Nakano, Yoshiyasu Aizawa, Kenshi Hayashi, Nobuyuki Murakoshi, Tadashi Nakajima, Nobue Yagihara, Hiroyuki Mishima, Takeaki Sudo, Chihiro Higuchi, Atsushi Takahashi, Akihiro Sekine, Takeru Makiyama, Yoshihiro Tanaka, Atsuyuki Watanabe, Motomi Tachibana, Hiroshi Morita, Koh-Ichiro Yoshiura, Tatsuhiko Tsunoda, Hiroshi Watanabe, Masahiko Kurabayashi, Akihiko Nogami, Yasuki Kihara, Minoru Horie, Wataru Shimizu, Naomasa Makita, Toshihiro Tanaka
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0277242 (2022)
Long QT syndrome (LQTS) is one of the most common inherited arrhythmias and multiple genes have been reported as causative. Presently, genetic diagnosis for LQTS patients is becoming widespread and contributing to implementation of therapies. However
Externí odkaz:
https://doaj.org/article/a19e4953468f4fa0aebed8e4a9b0d33a
Autor:
Rie Motoyama, Takashi Matsudaira, Kiyohito Terada, Naotaka Usui, Koh-ichiro Yoshiura, Yukitoshi Takahashi
Publikováno v:
Epilepsy & Behavior Reports, Vol 19, Iss , Pp 100554- (2022)
Proline-rich transmembrane protein 2 (PRRT2) was confirmed as the causative gene of paroxysmal kinesigenic dyskinesia (PKD) as shown by genome-wide linkage analyses. PRRT2 mutations are also associated with benign familial infantile seizures, infanti
Externí odkaz:
https://doaj.org/article/4178583808fe4f58b86d2122e1470179
Autor:
Hideki Kosako, Yusuke Yamashita, Ken Tanaka, Hiroyuki Mishima, Ryuta Iwamoto, Akira Kinoshita, Shin-ichi Murata, Koichi Ohshima, Koh-ichiro Yoshiura, Takashi Sonoki, Shinobu Tamura
Publikováno v:
Medicina, Vol 58, Iss 12, p 1830 (2022)
Background: Neurofibromatosis type 1 (NF1) is a hereditary cancer syndrome characterized by multiple café-au-lait macules on the skin. Lymphoproliferative malignancies associated with NF1 are limited, although the most common are brain tumors. Case
Externí odkaz:
https://doaj.org/article/5775c497e4f14ce590bc0ff13b5d8e21