Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Koga Komatsu"'
Autor:
Yuichiro Yamada, Hiroki Fujita, Takamune Takahashi, Mihoko Hosoba, Takuma Narita, Tsukasa Morii, Takuya Sakamoto, Koga Komatsu, Hiromi Fujishima, Keiko Takahashi
Publikováno v:
Hypertension Research
Renal superoxide excess, which is induced by an imbalance of the superoxide-producing enzyme NAD(P)H oxidase and the superoxide-scavenging enzyme superoxide dismutase (SOD) under hyperglycemia, increases oxidative stress and contributes to the develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2941b9acc8ab0a910d96a99d290d7f6
https://doi.org/10.1038/hr.2011.176
https://doi.org/10.1038/hr.2011.176
Autor:
Sumio Watanabe, Isao Wada, Masaru Odashima, Jinko Oyake, Tamotsu Matsuhashi, Reina Ohba, Mario Jin, Natsumi Hatakeyama, Raymond N. DuBois, Koga Komatsu, Michiro Otaka, Youhei Horikawa
Publikováno v:
Digestive Diseases and Sciences. 52:2757-2765
Resistance to chemotherapeutic agents is one of the distinct features of cancer cells. We evaluate the role of activated MEK-ERK signaling in Camptotecin/irinotecan (CPT-11)-induced cell death using constitutively activated MEK1-transfected normal ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::758f4b4c9c7cd69c57f772422d65263e
https://doi.org/10.1007/s10620-007-9798-0
https://doi.org/10.1007/s10620-007-9798-0
Autor:
Reina Ohba, Masaru Odashima, Michiro Otaka, Isao Wada, Hideaki Itoh, Youhei Horikawa, Natsumi Hatakeyama, Mario Jin, Koga Komatsu, Sumio Watanabe, Tamotsu Matsuhashi, Jinko Oyake
Publikováno v:
Alimentary Pharmacology & Therapeutics. 24:272-277
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b155f5b2c97f882fc546d0fdcb18ce45
https://doi.org/10.1111/j.1365-2036.2006.00056.x
https://doi.org/10.1111/j.1365-2036.2006.00056.x
Autor:
Keisuke Oikawa, Kenichi Miyazaki, Masanobu Ohwada, Sumio Watanabe, Hiromasa Kawasaki, Kazuyoshi Higuchi, Makoto Murata, Michiro Otaka, Koga Komatsu, Hideki Wakamatsu, Kanji Komatsu, Hiroshi Nanjo
Publikováno v:
Internal Medicine. 46:705-709
Follicular lymphoma of the small intestine remains relatively rare, especially in its early stage. Recently, double-balloon endoscopy has enabled observation of the entire small intestine. We describe a case of follicular lymphoma with multiple lesio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b78d5e637dc062fa7fb388ea8ec162
https://doi.org/10.2169/internalmedicine.46.6087
https://doi.org/10.2169/internalmedicine.46.6087
Autor:
Masaru Odashima, Tamotsu Matsuhashi, Sumio Watanabe, Reina Ohba, Mario Jin, Isao Wada, Noriaki Konishi, Hideaki Itoh, Michiro Otaka, Koga Komatsu, Youhei Horikawa
Publikováno v:
Biochemical and Biophysical Research Communications. 349:611-618
Background and aim The real mechanism of adaptive cytoprotection in the gastric mucosa is not well established. In the present study, we investigated the effect of acid suppressing agents on a 72-kDa heat shock protein (HSP72) expression, which is kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e2c9355c81fe0ffdb3186649a5bd9a7
https://doi.org/10.1016/j.bbrc.2006.08.088
https://doi.org/10.1016/j.bbrc.2006.08.088
Autor:
Isao Wada, Masaru Odashima, Jinko Oyake, Reina Ohba, Natsumi Hatakeyama, Tamotsu Matsuhashi, Hideaki Itoh, Sumio Watanabe, Mario Jin, Koga Komatsu, Michiro Otaka, Youhei Horikawa
Publikováno v:
Alimentary Pharmacology Therapeutics Symposium Series. 2:272-277
Summary Background Many recent studies have indicated the importance of heat shock proteins for cell survival under stress conditions. Some heat shock proteins are known to be involved in cytoprotection against environmental stresses, through their f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af9f23cea31cf2db9df95616350b4c80
https://doi.org/10.1111/j.1746-6342.2006.00056.x
https://doi.org/10.1111/j.1746-6342.2006.00056.x
Autor:
Reina Ohba, Michiro Otaka, Jinko Oyake, Youhei Horikawa, Masaru Odashima, Sumio Watanabe, Koga Komatsu, Natsumi Hatakeyama, Isao Wada, Tamotsu Matsuhashi, Mario Jin
Publikováno v:
Alimentary Pharmacology and Therapeutics. 21:42-46
Summary Background : In functional gastrointestinal (GI) disorders including functional dyspepsia (FD) and irritable bowel syndrome (IBS), there might be no small extent of contributions of psychosomatic factors. As a therapy for IBS patients, the ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9797575ca5d6719ee4f8b1acfcf9e23
https://doi.org/10.1111/j.1365-2036.2005.02473.x
https://doi.org/10.1111/j.1365-2036.2005.02473.x
Autor:
Jinko Oyake, Sumio Watanabe, Youhei Horikawa, Natsumi Hatakeyama, Masaru Odashima, Tamotsu Matsuhashi, Joel Linden, Isao Wada, Michiro Otaka, Koga Komatsu, Mario Jin, Reina Ohba
Publikováno v:
Journal of Gastroenterology. 40:526-529
D-Galactosamine (GalN)/lipopolysaccharide (LPS)-induced liver injury is an experimental model of fulminant hepatic failure in which tumor necrosis factor-alpha (TNF-alpha) plays a pivotal role. We examined the effects of a highly selective adenosine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12cfed9e18b1b01a741d3644c0725be2
https://doi.org/10.1007/s00535-005-1609-9
https://doi.org/10.1007/s00535-005-1609-9
Autor:
Sumio Watanabe, Reina Ohba, Masaru Odashima, Jinko Oyake, Tamotsu Matsuhashi, Joel Linden, Natsumi Hatakeyama, Isao Wada, Koga Komatsu, Michiro Otaka, Youhei Horikawa, Mario Jin
Publikováno v:
Journal of Gastroenterology and Hepatology. 20:275-280
Background: Activation of adenosine A2A receptors reduces the production of various pro-inflammatory cytokines and suppresses neutrophil activation. Water-immersion restraint is well known to cause gastric mucosal lesions due to stress. The pathogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f27e9851082024d0649d9250d4ff149
https://doi.org/10.1111/j.1440-1746.2004.03555.x
https://doi.org/10.1111/j.1440-1746.2004.03555.x
Autor:
Masaru Odashima, Koga Komatsu, Toshihiro Sato, Michiro Otaka, Sumio Watanabe, Sayuri Kato, Mario Jin, Ivan I. Pacheco Blandino, Noriaki Konishi
Publikováno v:
Journal of Gastroenterology and Hepatology. 16:1105-1111
BACKGROUND: Interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-alpha) are believed to play a significant role in the pathogenesis of inflammatory bowel disease (IBD). Interleukin-1 and TNF-alpha possess overlapping and synergetic activities in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::764cbcec2c267166d86012ac339493d8
https://doi.org/10.1046/j.1440-1746.2001.02584.x
https://doi.org/10.1046/j.1440-1746.2001.02584.x