Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Koffi L. Lakpa"'
Autor:
Regan Bradley, Koffi L. Lakpa, Michael Burd, Sunil Mehta, Maja Z. Katusic, Jacob R. Greenmyer
Publikováno v:
Nutrients, Vol 14, Iss 20, p 4223 (2022)
Prenatal alcohol exposure results in a spectrum of behavioral, cognitive, and morphological abnormalities collectively referred to as fetal alcohol spectrum disorder (FASD). FASD presents with significant phenotypic variability and may be modified by
Externí odkaz:
https://doaj.org/article/1ac1cfd861bc4096942f180cb6151b60
Autor:
Jonathan D. Geiger, Nabab Khan, Koffi L. Lakpa, Nicole M. Miller, Zahra Afghah, Peter W. Halcrow, Xuesong Chen, Steven F. Dowdy
Publikováno v:
The FASEB Journal
HIV‐1 Tat is essential for HIV‐1 replication and appears to play an important role in the pathogenesis of HIV‐associated neurological complications. Secreted from infected or transfected cells, Tat has the extraordinary ability to cross the pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b898e13c769d964d4d066dd3e2205e7a
https://doi.org/10.1096/fj.201902534r
https://doi.org/10.1096/fj.201902534r
Autor:
Jonathan D. Geiger, Koffi L. Lakpa, Nicole M. Miller, Nicholas H. Geiger, Xuesong Chen, Mahmoud L. Soliman, Liang Hui, Zahra Afghah
Publikováno v:
Journal of Alzheimer's Disease. 67:393-410
Cholesterol dyshomeostasis has been linked to the pathogenesis of sporadic Alzheimer's disease (AD). In furthering the understanding of mechanisms by which increased levels of circulating cholesterol augments the risk of developing sporadic AD, other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15e539ba279caa2839340282e2da6268
https://doi.org/10.3233/jad-180941
https://doi.org/10.3233/jad-180941
Publikováno v:
J Neuroimmune Pharmacol
Extensive work has characterized endoplasmic reticulum (ER) and mitochondrial stress responses. In contrast, very little has been published about stress responses in lysosomes; subcellular acidic organelles that are physiologically important and are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efefe5f1330d70613b3e6a4a837954b5
https://europepmc.org/articles/PMC8099033/
https://europepmc.org/articles/PMC8099033/
Autor:
Michael H Storandt, Michael Burd, Jacob R. Greenmyer, Vanessa Miller, Michelle Montgomery, Charles C. Hosford, Koffi L. Lakpa, Christopher Tiongson
Publikováno v:
Teaching and learning in medicine. 34(1)
Burnout is prevalent among medical students and is correlated with negative feelings, behaviors, and outcomes. Empathy is a desired trait for medical students that has been correlated with reduced burnout. The concept of guilt is closely related to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::472975a31e7b129d1e86a8ee4a432bb0
https://pubmed.ncbi.nlm.nih.gov/33722144
https://pubmed.ncbi.nlm.nih.gov/33722144
Autor:
Nabab Khan, Jonathan D. Geiger, Gaurav Datta, Koffi L. Lakpa, Nicole M. Miller, Xuesong Chen, Zahra Afghah, Peter W. Halcrow
Publikováno v:
J Neuroimmune Pharmacol
The HIV-1 coat protein gp120 continues to be implicated in the pathogenesis of HIV-1 associated neurocognitive disorder (HAND); a condition known to affect ~50% of people living with HIV-1 (PLWH). Autopsy brain tissues of HAND individuals display mor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef453a4a6ef2466a9fbc6c0963f9e682
https://pubmed.ncbi.nlm.nih.gov/33834418
https://pubmed.ncbi.nlm.nih.gov/33834418
Publikováno v:
Advances in experimental medicine and biology. 1131
Neurons are long-lived post-mitotic cells that possess an elaborate system of endosomes and lysosomes (endolysosomes) for protein quality control. Relatively recently, endolysosomes were recognized to contain high concentrations (400-600 μM) of read
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7ac97d80e7f3bd4ba26a7da585f42a21
https://pubmed.ncbi.nlm.nih.gov/31646530
https://pubmed.ncbi.nlm.nih.gov/31646530
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030124564
Neurons are long-lived post-mitotic cells that possess an elaborate system of endosomes and lysosomes (endolysosomes) for protein quality control. Relatively recently, endolysosomes were recognized to contain high concentrations (400–600 μM) of re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8658a29dbf827c6e96d27da7d54428aa
https://doi.org/10.1007/978-3-030-12457-1_27
https://doi.org/10.1007/978-3-030-12457-1_27
Autor:
Jonathan D. Geiger, Yan Ye, Xuesong Chen, Zahra Afghah, Liang Hui, Mahmoud L. Soliman, Koffi L. Lakpa, Nicole M. Miller
Publikováno v:
J Neuroimmune Pharmacol
Antiretroviral therapeutics (ART) have effectively increased the long-term survival of HIV-1 infected individuals. However, the prevalence of HIV-1 associated neurocognitive disorders (HAND) has increased and so too have clinical manifestations and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c34d2ad2077588be1be5446f75e010c
https://europepmc.org/articles/PMC6981001/
https://europepmc.org/articles/PMC6981001/
Autor:
Jonathan D. Geiger, Zahra Afghah, Peter W. Halcrow, Nabab Khan, Xuesong Chen, Koffi L. Lakpa, Nicole M. Miller
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
HIV-1 Tat is essential for HIV-1 replication and plays an important role in latent HIV-1 infection, HIV-1 associated neurological complication, and other HIV-1 comorbidities. Secreted from HIV-1 infected or transfected cells, Tat can be up-taken into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13024379a436ecfa3f286b206a7d7f35
https://pubmed.ncbi.nlm.nih.gov/31439883
https://pubmed.ncbi.nlm.nih.gov/31439883