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pro vyhledávání: '"Koeun Im"'
Autor:
Jin Chen, Ibironke Oduyebo, Michael Camilleri, Michael Badman, Yiming Zhang, Julian R.F. Walters, David S Sanders, Duane Burton, Koeun Im, Sara Linker Nord, Prafulla Bhad
Publikováno v:
Alimentary Pharmacology & Therapeutics. 52:808-820
Background In primary bile acid diarrhoea, feedback by farnesoid X receptor (FXR) and fibroblast growth hormone 19 (FGF19) on hepatic bile acid production is impaired. Aims To evaluate the safety, mechanisms and efficacy of negative feedback by FXR a