Zobrazeno 1 - 10
of 580
pro vyhledávání: '"Koetsier P"'
Autor:
Emma van den Eynde, Bibian van der Voorn, Leandra Koetsier, Hein Raat, Jaap C. Seidell, Jutka Halberstadt, Erica L. T. van den Akker
Publikováno v:
BMC Health Services Research, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Both the causes and consequences of childhood obesity can be complex. To provide healthcare that is suitably tailored to the specific needs of children with obesity integrated care is required. The objective of this study was to e
Externí odkaz:
https://doaj.org/article/7578cb42cb9344e1aca7506598f5010a
Autor:
Nasim Bahram Sangani, Jarno Koetsier, Jonathan Mélius, Martina Kutmon, Friederike Ehrhart, Chris T. Evelo, Leopold M. G. Curfs, Chris P. Reutelingsperger, Lars M. T. Eijssen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Due to its involvement in physiological and pathological processes, histone deacetylase 6 (HDAC6) is considered a promising pharmaceutical target for several neurological manifestations. However, the exact regulatory role of HDAC6 in the cen
Externí odkaz:
https://doaj.org/article/df6e6d5918da4d449dba8e00be5fbf47
Autor:
Corrado Cescon, Giuseppe Landolfi, Niko Bonomi, Marco Derboni, Vincenzo Giuffrida, Andrea Emilio Rizzoli, Paolo Maino, Eva Koetsier, Marco Barbero
Publikováno v:
JMIR mHealth and uHealth, Vol 12, Pp e53119-e53119 (2024)
Abstract BackgroundUnderstanding the causes and mechanisms underlying musculoskeletal pain is crucial for developing effective treatments and improving patient outcomes. Self-report measures, such as the Pain Drawing Scale, involve individuals ratin
Externí odkaz:
https://doaj.org/article/58000acca1294207b22f13fea810d6cc
Publikováno v:
European Journal of Psychotraumatology, Vol 15, Iss 1 (2024)
ABSTRACTBackground: Imagery rescripting (ImRs) has shown to be an effective treatment for posttraumatic stress disorders (PTSD) resulting from childhood-related trauma. The current theory is that the change of meaning of the trauma memory is central
Externí odkaz:
https://doaj.org/article/4b9305455d5f47f9922079211357b926
Autor:
Izdebski, Adam, Thoral, Patrick J., Lalisang, Robbert C. A., McHugh, Dean M., Gommers, Diederik, Cremer, Olaf L., Bosman, Rob J., Rigter, Sander, Wils, Evert-Jan, Frenzel, Tim, Dongelmans, Dave A., de Jong, Remko, Peters, Marco A. A., Kamps, Marlijn J. A, Ramnarain, Dharmanand, Nowitzky, Ralph, Nooteboom, Fleur G. C. A., de Ruijter, Wouter, Urlings-Strop, Louise C., Smit, Ellen G. M., Mehagnoul-Schipper, D. Jannet, Dormans, Tom, de Jager, Cornelis P. C., Hendriks, Stefaan H. A., Achterberg, Sefanja, Oostdijk, Evelien, Reidinga, Auke C., Festen-Spanjer, Barbara, Brunnekreef, Gert B., Cornet, Alexander D., Tempel, Walter van den, Boelens, Age D., Koetsier, Peter, Lens, Judith, Faber, Harald J., Karakus, A., Entjes, Robert, de Jong, Paul, Rettig, Thijs C. D., Arbous, Sesmu, Fleuren, Lucas M., Dam, Tariq A., Tonutti, Michele, de Bruin, Daan P., Elbers, Paul W. G., Cinà, Giovanni
Despite the recent progress in the field of causal inference, to date there is no agreed upon methodology to glean treatment effect estimation from observational data. The consequence on clinical practice is that, when lacking results from a randomiz
Externí odkaz:
http://arxiv.org/abs/2109.06707
Autor:
Maureen Markle-Reid, Kathryn Fisher, Kimberly M. Walker, Marla Beauchamp, Jill I. Cameron, David Dayler, Rebecca Fleck, Amiram Gafni, Rebecca Ganann, Ken Hajas, Barbara Koetsier, Robert Mahony, Chris Pollard, Jim Prescott, Tammy Rooke, Carly Whitmore
Publikováno v:
BMC Geriatrics, Vol 23, Iss 1, Pp 1-22 (2023)
Abstract Background This study aimed to test, in real-world clinical practice, the effectiveness of a Transitional Care Stroke Intervention (TCSI) compared to usual care on health outcomes, self-management, patient experience, and health and social s
Externí odkaz:
https://doaj.org/article/b174246e37a045e9b4d257e4b04a00a1
PP2A-B55alpha controls keratinocyte adhesion through dephosphorylation of the Desmoplakin C-terminus
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Critical for the maintenance of epidermal integrity and function are attachments between intermediate filaments (IF) and intercellular junctions called desmosomes. The desmosomal cytoplasmic plaque protein desmoplakin (DP) is essential for a
Externí odkaz:
https://doaj.org/article/57f9a37880ff4dfe8d2f72239da73708
Autor:
N. Dirkx, Wout J. Weuring, E. De Vriendt, N. Smal, J. van de Vondervoort, Ruben van ’t Slot, M. Koetsier, N. Zonnekein, Tim De Pooter, S. Weckhuysen, B. P. C. Koeleman
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Prime editing (PE) is the most recent gene editing technology able to introduce targeted alterations to the genome, including single base pair changes, small insertions, and deletions. Several improvements to the PE machinery have
Externí odkaz:
https://doaj.org/article/1f458b182d604f85b62a269b125c9ff9
Publikováno v:
Clinical Epidemiology, Vol Volume 15, Pp 721-732 (2023)
Irene Mommers,1 Job FM van Boven,2,3 Catharina CM Schuiling-Veninga,1 Jens HJ Bos,1 Marten Koetsier,1 Eelko Hak,1 Maarten J Bijlsma1,4 1Pharmacotherapy, Epidemiology and -Economics, University of Groningen, Groningen, the Netherlands; 2Groningen Rese
Externí odkaz:
https://doaj.org/article/357d5d60fc4e4c9a93c1c60673eb1184
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Restless legs syndrome is a prevalent, sleep-related sensorimotor disorder with relevant impact on the patients’ quality of life. For patients suffering from severe, pharmacoresistant restless legs syndrome, few therapeutic options remain to allevi
Externí odkaz:
https://doaj.org/article/6f4eaefb9eb6416193dbe5e8025f0153