Zobrazeno 1 - 10
of 575
pro vyhledávání: '"Koetsier, P."'
Autor:
Nasim Bahram Sangani, Jarno Koetsier, Jonathan Mélius, Martina Kutmon, Friederike Ehrhart, Chris T. Evelo, Leopold M. G. Curfs, Chris P. Reutelingsperger, Lars M. T. Eijssen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Due to its involvement in physiological and pathological processes, histone deacetylase 6 (HDAC6) is considered a promising pharmaceutical target for several neurological manifestations. However, the exact regulatory role of HDAC6 in the cen
Externí odkaz:
https://doaj.org/article/df6e6d5918da4d449dba8e00be5fbf47
Publikováno v:
European Journal of Psychotraumatology, Vol 15, Iss 1 (2024)
ABSTRACTBackground: Imagery rescripting (ImRs) has shown to be an effective treatment for posttraumatic stress disorders (PTSD) resulting from childhood-related trauma. The current theory is that the change of meaning of the trauma memory is central
Externí odkaz:
https://doaj.org/article/4b9305455d5f47f9922079211357b926
Autor:
Maureen Markle-Reid, Kathryn Fisher, Kimberly M. Walker, Marla Beauchamp, Jill I. Cameron, David Dayler, Rebecca Fleck, Amiram Gafni, Rebecca Ganann, Ken Hajas, Barbara Koetsier, Robert Mahony, Chris Pollard, Jim Prescott, Tammy Rooke, Carly Whitmore
Publikováno v:
BMC Geriatrics, Vol 23, Iss 1, Pp 1-22 (2023)
Abstract Background This study aimed to test, in real-world clinical practice, the effectiveness of a Transitional Care Stroke Intervention (TCSI) compared to usual care on health outcomes, self-management, patient experience, and health and social s
Externí odkaz:
https://doaj.org/article/b174246e37a045e9b4d257e4b04a00a1
Autor:
Izdebski, Adam, Thoral, Patrick J., Lalisang, Robbert C. A., McHugh, Dean M., Gommers, Diederik, Cremer, Olaf L., Bosman, Rob J., Rigter, Sander, Wils, Evert-Jan, Frenzel, Tim, Dongelmans, Dave A., de Jong, Remko, Peters, Marco A. A., Kamps, Marlijn J. A, Ramnarain, Dharmanand, Nowitzky, Ralph, Nooteboom, Fleur G. C. A., de Ruijter, Wouter, Urlings-Strop, Louise C., Smit, Ellen G. M., Mehagnoul-Schipper, D. Jannet, Dormans, Tom, de Jager, Cornelis P. C., Hendriks, Stefaan H. A., Achterberg, Sefanja, Oostdijk, Evelien, Reidinga, Auke C., Festen-Spanjer, Barbara, Brunnekreef, Gert B., Cornet, Alexander D., Tempel, Walter van den, Boelens, Age D., Koetsier, Peter, Lens, Judith, Faber, Harald J., Karakus, A., Entjes, Robert, de Jong, Paul, Rettig, Thijs C. D., Arbous, Sesmu, Fleuren, Lucas M., Dam, Tariq A., Tonutti, Michele, de Bruin, Daan P., Elbers, Paul W. G., Cinà, Giovanni
Despite the recent progress in the field of causal inference, to date there is no agreed upon methodology to glean treatment effect estimation from observational data. The consequence on clinical practice is that, when lacking results from a randomiz
Externí odkaz:
http://arxiv.org/abs/2109.06707
PP2A-B55alpha controls keratinocyte adhesion through dephosphorylation of the Desmoplakin C-terminus
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Critical for the maintenance of epidermal integrity and function are attachments between intermediate filaments (IF) and intercellular junctions called desmosomes. The desmosomal cytoplasmic plaque protein desmoplakin (DP) is essential for a
Externí odkaz:
https://doaj.org/article/57f9a37880ff4dfe8d2f72239da73708
Autor:
N. Dirkx, Wout J. Weuring, E. De Vriendt, N. Smal, J. van de Vondervoort, Ruben van ’t Slot, M. Koetsier, N. Zonnekein, Tim De Pooter, S. Weckhuysen, B. P. C. Koeleman
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Prime editing (PE) is the most recent gene editing technology able to introduce targeted alterations to the genome, including single base pair changes, small insertions, and deletions. Several improvements to the PE machinery have
Externí odkaz:
https://doaj.org/article/1f458b182d604f85b62a269b125c9ff9
Publikováno v:
Clinical Epidemiology, Vol Volume 15, Pp 721-732 (2023)
Irene Mommers,1 Job FM van Boven,2,3 Catharina CM Schuiling-Veninga,1 Jens HJ Bos,1 Marten Koetsier,1 Eelko Hak,1 Maarten J Bijlsma1,4 1Pharmacotherapy, Epidemiology and -Economics, University of Groningen, Groningen, the Netherlands; 2Groningen Rese
Externí odkaz:
https://doaj.org/article/357d5d60fc4e4c9a93c1c60673eb1184
Autor:
J. Halberstadt, L. W. Koetsier, M. Sijben, J. Stroo, M. van der Velde, E. G. A. H. van Mil, J. C. Seidell
Publikováno v:
BMC Health Services Research, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Background Childhood obesity is a chronic disease with negative physical and psychosocial health consequences. To manage childhood overweight and obesity, integrated care as part of an integrated approach is needed. To realise implementation
Externí odkaz:
https://doaj.org/article/0b07de77bb2849a89f3b3826cdf27aec
Autor:
Kaylee M. Keller, Joost Koetsier, Linda Schild, Vicky Amo-Addae, Selma Eising, Kim van den Handel, Kimberley Ober, Bianca Koopmans, Anke Essing, Marlinde L. van den Boogaard, Karin P. S. Langenberg, Natalie Jäger, Marcel Kool, Stefan Pfister, M. Emmy M. Dolman, Jan J. Molenaar, Sander R. van Hooff
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Pediatric cancer is the leading cause of disease-related death in children and the need for better therapeutic options remains urgent. Due to the limited number of patients, target and drug development for pediatrics is often supp
Externí odkaz:
https://doaj.org/article/89c1cc504cdf4e7d978144628845f2f7
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Restless legs syndrome is a prevalent, sleep-related sensorimotor disorder with relevant impact on the patients’ quality of life. For patients suffering from severe, pharmacoresistant restless legs syndrome, few therapeutic options remain to allevi
Externí odkaz:
https://doaj.org/article/6f4eaefb9eb6416193dbe5e8025f0153