RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated 2 differentiation via p73

Autor: Papaspyropoulos, Angelos, Bradley, Leanne, Thapa, Asmita, Leung, Chuen Yan, Toskas, Konstantinos, Koennig, Delia, Pefani, Dafni-Eleftheria, Raso, Cinzia, Grou, Claudia, Hamilton, Garth, Grawenda, Anna, Haider, Syed, Chauhan, Jagat, Buti, Ludovico, Kanapin, Alexander, Lu, Xin, Buffa, Francesca M, Dianov, Grigory, Von Kriegsheim, Alex, Matallanas, David, Samsonova, Anastasia, Zernicka-Goetz, Magdalena, O'Neill, Eric

Publikováno v: Papaspyropoulos, A, Bradley, L, Thapa, A, Leung, C Y, Toskas, K, Koennig, D, Pefani, D-E, Raso, C, Grou, C, Hamilton, G, Grawenda, A, Haider, S, Chauhan, J, Buti, L, Kanapin, A, Lu, X, Buffa, F M, Dianov, G, Von Kriegsheim, A, Matallanas, D, Samsonova, A, Zernicka-Goetz, M & O'Neill, E 2018, ' RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated 2 differentiation via p73 ', Nature Communications . https://doi.org/10.1038/s41467-017-02786-5

Transition from pluripotency to differentiation is a pivotal yet poorly understooddevelopmental step. Here we show that the tumour suppressor RASSF1A is a key player driving the early specification of cell fate. RASSF1A acts as a natural barrier to s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3094::b707ee9c6d13e1ee5d039d140fc9bfec
https://hdl.handle.net/20.500.11820/8bcb2014-e4e1-4b0f-a11f-33a99c655df6

RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated differentiation via p73.

Autor: Papaspyropoulos, Angelos, Bradley, Leanne, Thapa, Asmita, Chuen Yan Leung, Toskas, Konstantinos, Koennig, Delia, Pefani, Dafni-Eleftheria, Raso, Cinzia, Grou, Claudia, Hamilton, Garth, Vlahov, Nikola, Grawenda, Anna, Haider, Syed, Chauhan, Jagat, Buti, Ludovico, Kanapin, Alexander, Xin Lu, Buffa, Francesca, Dianov, Grigory, von Kriegsheim, Alex

Publikováno v: Nature Communications; 1/30/2018, Vol. 9 Issue 1, p1-15, 15p