Curbing gastrointestinal infections by defensin fragment modifications without harming commensal microbiota.

Autor: Koeninger, Louis¹ louis.koeninger@med.uni-tuebingen.de, Osbelt, Lisa^2,3, Berscheid, Anne^4,5, Wendler, Judith¹, Berger, Jürgen⁶, Hipp, Katharina⁶, Lesker, Till R.², Pils, Marina C.⁷, Malek, Nisar P.¹, Jensen, Benjamin A. H.⁸, Brötz-Oesterhelt, Heike^4,5,9, Strowig, Till^2,10, Jan Wehkamp^1,9

Publikováno v: Communications Biology. 1/8/2021, Vol. 4 Issue 1, p1-11. 11p.

Human β-Defensin 2 Mediated Immune Modulation as Treatment for Experimental Colitis

Autor: Koeninger, Louis, Armbruster, Nicole S., Brinch, Karoline Sidelmann, Kjaerulf, Søren, Andersen, Birgitte, Langnau, Carolin, Autenrieth, Stella E., Schneidawind, Dominik, Stange, Eduard F., Malek, Nisar P., Nordkild, Peter, Jensen, Benjamin A.H., Wehkamp, Jan

Publikováno v: Frontiers in Immunology
Koeninger, L, Armbruster, N S, Brinch, K S, Kjaerulf, S, Andersen, B, Langnau, C, Autenrieth, S E, Schneidawind, D, Stange, E F, Malek, N P, Nordkild, P, Jensen, B A H & Wehkamp, J 2020, ' Human β-Defensin 2 Mediated Immune Modulation as Treatment for Experimental Colitis ', Frontiers in Immunology, vol. 11, 93 . https://doi.org/10.3389/fimmu.2020.00093

Defensins represents an integral part of the innate immune system serving to ward off potential pathogens and to protect the intestinal barrier from microbial encroachment. In addition to their antimicrobial activities, defensins in general, and huma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6520c40aa9b123ef98fc3b78806986c1
http://europepmc.org/articles/PMC7006816

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Human β‐defensin‐2 suppresses key features of asthma in murine models of allergic airways disease.

Autor: Pinkerton, James W., Kim, Richard Y., Koeninger, Louis, Armbruster, Nicole S., Hansbro, Nicole G., Brown, Alexandra C., Jayaraman, Ranjith, Shen, Sijie, Malek, Nisar, Cooper, Matthew A., Nordkild, Peter, Horvat, Jay C., Jensen, Benjamin A. H., Wehkamp, Jan, Hansbro, Philip M.

Publikováno v: Clinical & Experimental Allergy; Jan2021, Vol. 51 Issue 1, p120-131, 12p, 1 Color Photograph, 1 Chart, 6 Graphs

129 - Oral Delivery of Human Beta-Defensin 2 is Reversibly Increasing Microbiome Diversity and is Effective in the Treatment of Experimental Colitis

Autor: Koeninger, Louis, Armbruster, Nicole S., Hu, Zexi, Jensen, Benjamin, Stange, Eduard, Nordkild, Peter, Malek, Nisar P., Zender, Lars, Wehkamp, Jan

Publikováno v: In Gastroenterology May 2018 154(6) Supplement 1:S