Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Koen Vermeulen"'
Autor:
Anthony Waked, Melissa Crabbé, Virginie Neirinckx, Sunay Rodriguez Pérez, Jasmien Wellens, Bernard Rogister, M. Abderrafi Benotmane, Koen Vermeulen
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-23 (2024)
Abstract Background Glioblastoma (GBM), is the most fatal form of brain cancer, with a high tendency for recurrence despite combined treatments including surgery, radiotherapy, and chemotherapy with temozolomide. The C-X-C chemokine receptor 4 (CXCR4
Externí odkaz:
https://doaj.org/article/2daae8f923c24ea9b4dc2fcf7ade3ca4
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 8, Iss 1, Pp 1-19 (2023)
Abstract Background The molecular chaperone, Hsp90, is a key player in the protein quality control system that maintains homeostasis under cellular stress conditions. It is a homodimer with ATP-dependent activity, and is a prominent member of the cha
Externí odkaz:
https://doaj.org/article/d81edcc59a5149ba89dfec3f06e45721
Publikováno v:
Pharmaceuticals, Vol 16, Iss 5, p 692 (2023)
The radionuclide therapy [177Lu]Lu-PSMA-617 was recently FDA-approved for treatment of metastatic castration-resistant prostate cancer. Salivary gland toxicity is currently considered as the main dose-limiting side effect. However, its uptake and ret
Externí odkaz:
https://doaj.org/article/187c9ca27c5646a6909a900265206f91
Autor:
Koen Vermeulen, Michiel Van de Voorde, Charlotte Segers, Amelie Coolkens, Sunay Rodriguez Pérez, Noami Daems, Charlotte Duchemin, Melissa Crabbé, Tomas Opsomer, Clarita Saldarriaga Vargas, Reinhard Heinke, Laura Lambert, Cyril Bernerd, Andrew R. Burgoyne, Thomas Elias Cocolios, Thierry Stora, Maarten Ooms
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2566 (2022)
Samarium-153 is a promising theranostic radionuclide, but low molar activities (Am) resulting from its current production route render it unsuitable for targeted radionuclide therapy (TRNT). Recent efforts combining neutron activation of 152Sm in the
Externí odkaz:
https://doaj.org/article/bf8a094d04184b509d6e9a3d216dfaea
Background The molecular chaperone, Hsp90, is a key player in the protein quality control system that maintains homeostasis under cellular stress conditions. It is a homodimer with ATP-dependent activity, and is a prominent member of the chaperone ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::377ac70140c8a0ac66ddadc25831ec46
https://doi.org/10.21203/rs.3.rs-2322542/v1
https://doi.org/10.21203/rs.3.rs-2322542/v1
Autor:
Christopher Cawthorne, Emmanuelle Briard, Guy Bormans, Romy Cools, Joseph Schoepfer, Michel Koole, Yves Auberson, Koen Vermeulen
Publikováno v:
ACS Chemical Neuroscience. 12:3915-3927
Aberrant Hsp90 has been implied in cancer and neurodegenerative disorders. The development of a suitable Hsp90 Positron emission tomography (PET) probe can provide in vivo quantification of the expression levels of Hsp90 as a biomarker for diagnosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99892b5799e4ca47def1b75410e2383a
https://doi.org/10.1021/acschemneuro.1c00508
https://doi.org/10.1021/acschemneuro.1c00508
Publikováno v:
NUCLEAR MEDICINE AND BIOLOGY
At present, prostate cancer remains the second most occurring cancer in men, in Europe. Treatment efficacy for therapy of advanced metastatic disease, and metastatic castration-resistant prostate cancer in particular is limited. Prostate-specific mem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15043b2fcdb486077d8454d818ae7171
https://doi.org/10.1016/j.nucmedbio.2021.04.003
https://doi.org/10.1016/j.nucmedbio.2021.04.003
Publikováno v:
Handbook of Radiopharmaceuticals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4f458e2a60a36fe670db01c045dc030
https://doi.org/10.1002/9781119500575.ch17
https://doi.org/10.1002/9781119500575.ch17
Autor:
Irwin Cassells, Michiel Van de Voorde, Koen Vermeulen, Sunay Rodriguez, Charlotte Segers, Christopher Cawthorne, Christophe Deroose, Thomas Cardinaels, Guy Bormans, Maarten Ooms, Frederik Cleeren
Publikováno v:
Nuclear Medicine and Biology. :S50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2a570d64df88e67d17f90291d46b423
https://doi.org/10.1016/s0969-8051(22)02191-6
https://doi.org/10.1016/s0969-8051(22)02191-6
Autor:
Koen Vermeulen, Michiel Van de Voorde, Noami Daems, Charlotte Duchemin, Sunay Rodriguez, Melissa Crabbé, Reinhard Heinke, Bernard Ponsard, Lorain Geenen, Julie Nonnekens, Laura Lambert, Charlotte Segers, Cyril Bernerd, Andrew Burgoyne, Thomas Cocolios, Thierry Stora, Maarten Ooms
Publikováno v:
Nuclear Medicine and Biology. :S57
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be6e6c13929822facc3d0739af699e1e
https://doi.org/10.1016/s0969-8051(22)02206-5
https://doi.org/10.1016/s0969-8051(22)02206-5