Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Koen Van Acker"'
Autor:
Géry Dams, Rudi Pauwels, Kurt Hertogs, Christel Van den Eynde, Erik Nijs, Eva Bettens, Tania Ivens, Asa Ohagen, Koen Van Acker
Publikováno v:
Journal of Virological Methods
The severity and global spread of the 2003 outbreak of the severe acute respiratory syndrome-associated coronavirus (SARS-CoV) highlighted the risks to human health posed by emerging viral diseases and emphasized the need for specific therapeutic age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::632d8dff6698986c3cedff37112d5de9
https://doi.org/10.1016/j.jviromet.2005.05.010
https://doi.org/10.1016/j.jviromet.2005.05.010
Autor:
Tania Ivens, Géry Dams, John Hansen, Christel Van den Eynde, Erik Nijs, Marnix Van Loock, Lieve Bunkens, Sarah Sauviller, Koen Van Acker, Peggy Geluykens
Publikováno v:
Assay and drug development technologies. 11(8)
Cell-based high-throughput screening campaigns are widely used to identify novel antiviral compounds, for example, against human immunodeficiency virus type 1 (HIV-1). Typically, these assays enable identification of compounds that potentially target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23e038eafbcff88addc05b86f05009ff
https://pubmed.ncbi.nlm.nih.gov/24144343
https://pubmed.ncbi.nlm.nih.gov/24144343
Autor:
Liesbet, Smeulders, Lieve, Bunkens, Inge, Vereycken, Koen, Van Acker, Pascale, Holemans, Emmanuel, Gustin, Marnix, Van Loock, Géry, Dams
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1030
The human immunodeficiency virus type 1 (HIV-1) initiates infection through sequential interactions with CD4 and chemokine coreceptors unmasking the gp41 subunit of the viral envelope protein. Consequently, the N-terminal heptad repeats of gp41 form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::249e1dc2b1103dbfbabe954500dbc315
https://pubmed.ncbi.nlm.nih.gov/23821256
https://pubmed.ncbi.nlm.nih.gov/23821256
Autor:
Peggy, Geluykens, Koen, Van Acker, Johan, Vingerhoets, Christel, Van den Eynde, Marnix, Van Loock, Géry, Dams
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1030
Highly active antiretroviral therapy (HAART) dramatically increases the long-term survival rates of human immunodeficiency virus type 1 (HIV-1) infected patients. Yet, poor adherence to therapy, adverse effects and the occurrence of resistant viruses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c62670e78d68c4b0e2e10c4a72290023
https://pubmed.ncbi.nlm.nih.gov/23821255
https://pubmed.ncbi.nlm.nih.gov/23821255
Autor:
Inge Vereycken, Koen Van Acker, Emmanuel Gustin, Marnix Van Loock, Liesbet Smeulders, Lieve Bunkens, Géry Dams, Pascale Holemans
Publikováno v:
Antiviral Methods and Protocols ISBN: 9781627034838
The human immunodeficiency virus type 1 (HIV-1) initiates infection through sequential interactions with CD4 and chemokine coreceptors unmasking the gp41 subunit of the viral envelope protein. Consequently, the N-terminal heptad repeats of gp41 form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72e3161740dcee62c7b188e1532f5995
https://doi.org/10.1007/978-1-62703-484-5_2
https://doi.org/10.1007/978-1-62703-484-5_2
Autor:
Peggy Geluykens, Marnix Van Loock, Géry Dams, Johan Vingerhoets, Christel Van den Eynde, Koen Van Acker
Publikováno v:
Antiviral Methods and Protocols ISBN: 9781627034838
Highly active antiretroviral therapy (HAART) dramatically increases the long-term survival rates of human immunodeficiency virus type 1 (HIV-1) infected patients. Yet, poor adherence to therapy, adverse effects and the occurrence of resistant viruses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c5ec350c4e2bde1c42edfdc667edac8
https://doi.org/10.1007/978-1-62703-484-5_1
https://doi.org/10.1007/978-1-62703-484-5_1
Autor:
Bertrand, Van Schoubroeck, Koen, Van Acker, Géry, Dams, Dirk, Jochmans, Reginald, Clayton, Jan Martin, Berke, Sam, Lievens, José, Van der Heyden, Jan, Tavernier
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 812
The discovery of novel antivirals for HIV and HCV has been a focus of intensive research for many years. Where the inhibition of critical viral enzymes by small molecules has proven effective for many viruses, there is considerable merit in pursuing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4f889ecc4aaf49550ce326c256a91fb4
https://pubmed.ncbi.nlm.nih.gov/22218868
https://pubmed.ncbi.nlm.nih.gov/22218868
Autor:
Bertrand Van Schoubroeck, Géry Dams, Reginald Clayton, Dirk Jochmans, Sam Lievens, Jan Tavernier, José Van der Heyden, Koen Van Acker, Jan Martin Berke
Publikováno v:
Methods in Molecular Biology ISBN: 9781617794544
The discovery of novel antivirals for HIV and HCV has been a focus of intensive research for many years. Where the inhibition of critical viral enzymes by small molecules has proven effective for many viruses, there is considerable merit in pursuing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f85d344ec5d3415dbf11d3af7baefb89
https://doi.org/10.1007/978-1-61779-455-1_18
https://doi.org/10.1007/978-1-61779-455-1_18
Autor:
Emmanuel Gustin, Asa Ohagen, Lieve Elisabeth Louis Bunkens, Inge Vereycken, Reginald Clayton, Liesbet Smeulders, Koen Van Acker, Kurt Hertogs, Géry Dams, Pascale Holemans
Publikováno v:
Journal of biomolecular screening. 12(6)
Fusion of host cell and human immunodeficiency virus type 1 (HIV-1) membranes is mediated by the 2 “heptad-repeat” regions of the viral gp41 protein. The collapse of the C-terminal heptad-repeat regions into the hydrophobic grooves of a coiled-co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a870306a7184017c460c25f44679eee
https://pubmed.ncbi.nlm.nih.gov/17644771
https://pubmed.ncbi.nlm.nih.gov/17644771
Autor:
Tania Ivens, Koen Van Acker, Mark M. Kockx, Inky De Baere, Isabelle Vanden Bempt, Erwin Sablon, Benoit Devogelaere, Pascale Holemans, Evelien Rondelez, Ina Vandenbroucke, Geneviève Vandercruyssen, Bart Claes, Marijke Van der Auwera, Geert Maertens
Publikováno v:
Cancer Research. 73:4213-4213
Introduction Activating mutations in the BRAF gene are common in skin and colorectal tumors. In more than 90% of the cases, these mutations are located in the BRAF V600 codon (V600E and V600K). Targeted therapies like vemurafenib and dabrafenib have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::217de6736aa01477909bad96cd1793f6
https://doi.org/10.1158/1538-7445.am2013-4213
https://doi.org/10.1158/1538-7445.am2013-4213