Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Koen R D Vaessen"'
Autor:
Eva L van Donkelaar, Koen R D Vaessen, Jodi L Pawluski, Annerieke S Sierksma, Arjan Blokland, Ramón Cañete, Harry W M Steinbusch
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e106960 (2014)
Chronic stress or long-term administration of glucocorticoids disrupts the hypothalamus-pituitary-adrenal system leading to continuous high levels of glucocorticoids and insulin resistance (IR). This pre-diabetic state can eventually develop into typ
Externí odkaz:
https://doaj.org/article/79396bb81b664f64b2ad19b62bea12a0
Autor:
Joost C. de Vries, Maaike K. van Gelder, Anneke S. Monninkhof, Sabbir Ahmed, Diënty H. M. Hazenbrink, Tri Q. Nguyen, Gèrard A. P. de Kort, Evert-Jan P. A. Vonken, Koen R. D. Vaessen, Jaap A. Joles, Marianne C. Verhaar, Karin G. F. Gerritsen
Publikováno v:
Toxins, Vol 14, Iss 9, p 635 (2022)
With increasing interest in home dialysis, there is a need for a translational uremic large animal model to evaluate technical innovations in peritoneal dialysis (PD). To this end, we developed a porcine model with kidney failure. Stable chronic kidn
Externí odkaz:
https://doaj.org/article/aa5fadff8d85457a9da6eea6c7408896
Autor:
Maaike K. van Gelder, Jasper Stevens, Tobias T. Pieters, Koen R. D. Vaessen, Jaap A. Joles, Marianne C. Verhaar, Karin G. F. Gerritsen
Publikováno v:
Biology, Vol 10, Iss 6, p 461 (2021)
The preclinical evaluation of novel therapies for chronic kidney disease requires a simple method for the assessment of kidney function in a uremic large animal model. An intravenous bolus of iohexol was administered to goats (13 measurements in n =
Externí odkaz:
https://doaj.org/article/38f7e1745b584b3a8fc55b0e80e49aa8
Autor:
Maaike K. van Gelder, Joost C. de Vries, Sabbir Ahmed, Anneke S. Monninkhof, Gérard A. P. de Kort, Evert-Jan P. A. Vonken, Diënty H. M. Hazenbrink, Koen R. D. Vaessen, Tri Q. Nguyen, Marianne C. Verhaar, Jaap A. Joles, Karin G. F. Gerritsen
Publikováno v:
Biology, Vol 10, Iss 4, p 292 (2021)
A large animal model of (end-stage) kidney disease (ESKD) is needed for the preclinical testing of novel renal replacement therapies. This study aimed to create stable uremia via subtotal renal artery embolization in goats and induce a temporary furt
Externí odkaz:
https://doaj.org/article/d15d18d703ad47018f1cf55836d37dd7
Autor:
de Vries, Joost, van Gelder, Maaike K., S Monninkhof, Anneke, Ahmed, Sabbir, Hazenbrink, Diënty, Nguyen, Tri Q, Gèrard A P de Kort, Gèrard, P A Vonken, Evert-Jan, Koen R D Vaessen, Koen, Joles, Jaap A., Verhaar, Marianne C., Gerritsen, Karin G.F., Afd Pharmacology, Pharmacology, Pharmaceutics
Publikováno v:
Toxins; Volume 14; Issue 9; Pages: 635
Toxins, 14(9). MDPI AG
Toxins, 14(9). MDPI AG
With increasing interest in home dialysis, there is a need for a translational uremic large animal model to evaluate technical innovations in peritoneal dialysis (PD). To this end, we developed a porcine model with kidney failure. Stable chronic kidn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::285844f07621dddd705f401caf50961f
Autor:
Simone M. J. de Jong, Sylvia Dekker, Serena Buscone, Merle M. Krebber, Eva Brauchle, Emily B. Lurier, Koen R D Vaessen, Renee Duijvelshoff, Daniel A Carvajal-Berrio, Suzanne E Koch, Valentina Bonito, Carlijn V. C. Bouten, Patricia Y. W. Dankers, Anthal I.P.M. Smits, Marianne C. Verhaar, Tristan Mes, Katja Schenke-Layland, Anton W. Bosman, Julia Marzi
Publikováno v:
Advanced Healthcare Materials, 10(21):e2101103. Wiley
Two of the greatest challenges for successful application of small-diameter in situ tissue-engineered vascular grafts are 1) preventing thrombus formation and 2) harnessing the inflammatory response to the graft to guide functional tissue regeneratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::502cdea427bc26e7062cf61b1d199eed
https://pubmed.ncbi.nlm.nih.gov/34523263
https://pubmed.ncbi.nlm.nih.gov/34523263
Autor:
Karin G.F. Gerritsen, Jasper Stevens, Tobias T Pieters, Maaike K. van Gelder, Jaap A. Joles, Marianne C. Verhaar, Koen R D Vaessen
Publikováno v:
Biology
Volume 10
Issue 6
Biology, Vol 10, Iss 461, p 461 (2021)
Biology, 10(6):461. MDPI AG
Volume 10
Issue 6
Biology, Vol 10, Iss 461, p 461 (2021)
Biology, 10(6):461. MDPI AG
The preclinical evaluation of novel therapies for chronic kidney disease requires a simple method for the assessment of kidney function in a uremic large animal model. An intravenous bolus of iohexol was administered to goats (13 measurements in n =
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e384722d621fe32bc05f059347040699
Autor:
Saskia Redegeld, Ahmet Kinaci, Koen R D Vaessen, Tristan P.C. van Doormaal, Albert van der Zwan
Publikováno v:
Laboratory animals. 55(5)
A large craniotomy survival porcine model is useful for scientific research. The surgical approaches and complications of craniotomies in pigs have not been published before. This study describes how large craniotomies were performed in 46 pigs and h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa3272af42a9e05e5997739df67fa92d
https://pubmed.ncbi.nlm.nih.gov/34018879
https://pubmed.ncbi.nlm.nih.gov/34018879
Autor:
Sabbir Ahmed, Karin G.F. Gerritsen, Anneke S Monninkhof, Tri Q. Nguyen, Gerard A. P. de Kort, Maaike K. van Gelder, Koen R D Vaessen, Diënty H M Hazenbrink, Joost C de Vries, Evert-Jan Vonken, Jaap A. Joles, Marianne C. Verhaar
Publikováno v:
Biology
Volume 10
Issue 4
Biology, Vol 10, Iss 292, p 292 (2021)
Volume 10
Issue 4
Biology, Vol 10, Iss 292, p 292 (2021)
Simple Summary To improve the treatment of patients with kidney disease, new renal replacement therapies are being developed. Prior to their use in humans with end-stage kidney disease (ESKD), these therapies need to be tested in animals with kidney
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c12512300b6e97bc79e85ab0c8877fbf
http://europepmc.org/articles/PMC8066079
http://europepmc.org/articles/PMC8066079
Autor:
Frank Simonis, Karin G.F. Gerritsen, Maarten Wester, Maaike K. van Gelder, Diënty H M Hazenbrink, Koen R D Vaessen, Jaap A. Joles, Theo W. M. van Berkel, Walther H. Boer, Marianne C. Verhaar
Publikováno v:
American Journal of Physiology-Renal Physiology
The key to success in developing a wearable dialysis device is a technique to safely and efficiently regenerate and reuse a small volume of dialysate in a closed-loop system. In a hemodialysis model in goats, we explored whether urea removal by elect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf2c4b7ee0816bdd7e4b4454b033ba5e
https://pubmed.ncbi.nlm.nih.gov/29993277
https://pubmed.ncbi.nlm.nih.gov/29993277