Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Koen M Marien"'
Autor:
Koen M Marien, Valerie Croons, Yannick Waumans, Ellen Sluydts, Stefanie De Schepper, Luc Andries, Wim Waelput, Erik Fransen, Peter B Vermeulen, Mark M Kockx, Guido R Y De Meyer
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0161496 (2016)
Despite all efforts made to develop predictive biomarkers for antiangiogenic therapies, no unambiguous markers have been identified so far. This is due to among others the lack of standardized tests. This study presents an improved microvessel densit
Externí odkaz:
https://doaj.org/article/421154d6011b40f5a40660f694122414
Autor:
Zineb Mounir, Mark R. Lackner, Shih-Min A. Huang, Yannick Waumans, Mark Kockx, Koen M. Marien, Sarah Lynagh, Paul R. McAdam, Max Bylesjo, Adrian R. Carr, Daniel L. Halligan, Sanjeev Mariathasan, Edward E. Kadel, Kobe C. Yuen, Thomas Holcomb, Shrividhya Srinivasan, Joseph Castillo, Marie-Claire Wagle
supplementary tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35073d94791ff25b6df92ad645e456c1
https://doi.org/10.1158/2326-6066.22543155.v1
https://doi.org/10.1158/2326-6066.22543155.v1
Supplementary Fig 1 from Tumor Fusion Burden as a Hallmark of Immune Infiltration in Prostate Cancer
Autor:
Zineb Mounir, Mark R. Lackner, Shih-Min A. Huang, Yannick Waumans, Mark Kockx, Koen M. Marien, Sarah Lynagh, Paul R. McAdam, Max Bylesjo, Adrian R. Carr, Daniel L. Halligan, Sanjeev Mariathasan, Edward E. Kadel, Kobe C. Yuen, Thomas Holcomb, Shrividhya Srinivasan, Joseph Castillo, Marie-Claire Wagle
TMB, TFB and CRPC scores across individual samples and disease stages and crosscorrelation analyses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9124389488a6abd15abccd6bbf624d28
https://doi.org/10.1158/2326-6066.22543161.v1
https://doi.org/10.1158/2326-6066.22543161.v1
Autor:
Zineb Mounir, Mark R. Lackner, Shih-Min A. Huang, Yannick Waumans, Mark Kockx, Koen M. Marien, Sarah Lynagh, Paul R. McAdam, Max Bylesjo, Adrian R. Carr, Daniel L. Halligan, Sanjeev Mariathasan, Edward E. Kadel, Kobe C. Yuen, Thomas Holcomb, Shrividhya Srinivasan, Joseph Castillo, Marie-Claire Wagle
Prostate cancer is the second leading cause of cancer-related death in men. Despite having a relatively lower tumor mutational burden than most tumor types, multiple gene fusions such as TMPRSS2:ERG have been characterized and linked to more aggressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e25bc093bffce3f195eb2bcc044f33
https://doi.org/10.1158/2326-6066.c.6550161.v1
https://doi.org/10.1158/2326-6066.c.6550161.v1
Publikováno v:
MethodsX, Vol 2, Iss C, Pp 272-277 (2015)
Tumor angiogenesis is measured by counting microvessels in tissue sections at high power magnification as a potential prognostic or predictive biomarker. Until now, regions of interest1 1 ROI: region of interest. (ROIs) were selected by manual operat
Externí odkaz:
https://doaj.org/article/1400f62ca2044308a248a0077dabcd0f
Autor:
Lore Decoster, Erik Teugels, Sacha Mignon, Johan Vansteenkiste, Karen Willard-Gallo, Gert Van den Eynden, Roberto Salgado, Koen M. Marien, Jacques De Greve
Publikováno v:
Pathology and oncology research
Tumor infiltrating lymphocytes (TIL), programmed death 1 (PD-1) and programmed death-ligand 1 (PD-L1) expression are important prognostic markers. This study aimed to investigate these markers in lung adenocarcinoma (ADC) biopsies from patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87443eb08272d6c76e668b3d9c3e84d7
https://doi.org/10.1007/s12253-019-00670-9
https://doi.org/10.1007/s12253-019-00670-9
Stromal marker fibroblast activation protein drives outcome in T1 non-muscle invasive bladder cancer
Autor:
Koen M. Marien, Yannick Waumans, Thomas Gevaert, Tim Muilwijk, Thomas Van den Broeck, Frank Van der Aa, Mark M. Kockx, Murat Akand, Steven Joniau, Loïc Baekelandt, Sofie Daelemans
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0257195 (2021)
PLoS ONE, Vol 16, Iss 9, p e0257195 (2021)
Fibroblast activation protein-α (FAP) is a transmembrane peptidase and a surrogate marker for cancer-associated fibroblasts (CAFs). FAP has been linked to worse prognosis and therapy resistance in several cancers. We hypothesised that FAP might have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0042c9aa6d61d97f630530102c538be7
https://hdl.handle.net/10067/1825270151162165141
https://hdl.handle.net/10067/1825270151162165141
Autor:
Mark M. Kockx, S. Van Laere, Yannick Waumans, C. Rypens, Koen M. Marien, C. Van Berckelaer, C Colpaert, P. van Dam, L.Y. Dirix, Peter B. Vermeulen
Publikováno v:
Cancer Research. 79:P4-06
Introduction The mechanisms contributing to the aggressive biology of inflammatory breast cancer (IBC) are still under investigation. Our lab reported a 79-gene signature that is shaped by specific immune response programs and discriminates between I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37eda4dd685b36ffe3c4e0c9824d9f2e
https://doi.org/10.1158/1538-7445.sabcs18-p4-06-08
https://doi.org/10.1158/1538-7445.sabcs18-p4-06-08
Autor:
Mark M. Kockx, Edward E. Kadel, Max Bylesjö, Shrividhya Srinivasan, Shih-Min A. Huang, Daniel L. Halligan, Koen M. Marien, Kobe C. Yuen, Sanjeev Mariathasan, Zineb Mounir, Joseph Castillo, Yannick Waumans, Paul R. McAdam, Sarah Lynagh, Adrian R. Carr, Thomas Holcomb, Mark R. Lackner, Marie-Claire Wagle
Publikováno v:
Cancer immunology research. 8(7)
Prostate cancer is the second leading cause of cancer-related death in men. Despite having a relatively lower tumor mutational burden than most tumor types, multiple gene fusions such as TMPRSS2:ERG have been characterized and linked to more aggressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cfb8a92d44c056c01dfc3b4d4dca400
https://pubmed.ncbi.nlm.nih.gov/32321776
https://pubmed.ncbi.nlm.nih.gov/32321776
Autor:
Steven Van Laere, Mark M. Kockx, Peter B. Vermeulen, Peter van Dam, Cecile Colpaert, Peter A. van Dam, Koen M. Marien, Christophe Van Berckelaer, C. Rypens, Luc Dirix
Publikováno v:
Journal of Clinical Oncology. 38:3086-3086
3086 Background: The mechanisms contributing to the aggressive biology of inflammatory breast cancer (IBC) are under investigation. A specific immune response seems to be an important driver, but the functional role of infiltrating immune cells in IB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d77e85bf46e7ed029e84b6b6572072e
https://doi.org/10.1200/jco.2020.38.15_suppl.3086
https://doi.org/10.1200/jco.2020.38.15_suppl.3086