Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Koen Iterbeke"'
Autor:
Maarten Timmers, Koen Iterbeke, Romana Petrovic, Richard M. W. Hoetelmans, Magda Opsomer, Tom Van De Casteele, Vera Hillewaert, Thomas N. Kakuda
Publikováno v:
The Journal of Clinical Pharmacology. 54:949-957
This study compared the bioavailability of two candidate fixed-dose combinations (FDCs: G003 and G004) of darunavir/cobicistat 800/150 mg with that of darunavir 800 mg and ritonavir 100 mg coadministered as single agents. Short-term safety and tolera
Autor:
Fred Stappers, Alfons Wouters, Koen Iterbeke, Francois Marc Karel Jozef, Guenter Kraus, Piet Wigerinck, Laurent Schueller, Lieven Baert, Pieter Van Remoortere, Esther Dina Guido Basstanie, Gerben Albert Eleutherius Van 'T Klooster, Willy Maria Albert Carlo Dries, Jan Rosier, Paul Stevens
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 72:502-508
Long-acting parenteral formulations of antiretrovirals could facilitate maintenance and prophylactic treatment in HIV. Using the poorly water- and oil-soluble non-nucleoside reverse transcriptase inhibitor (NNRTI) TMC278 (rilpivirine) as base or hydr
Autor:
Tom Van De Casteele, Thomas N. Kakuda, Frank Tomaka, Goedele De Smedt, Herta Crauwels, Simon Vanveggel, Koen Iterbeke, Magda Opsomer
Publikováno v:
Expert review of anti-infective therapy. 13(6)
A current focus in HIV management is improving adherence by minimizing pill burden with convenient formulations, including fixed-dose combinations (FDCs). Darunavir, a HIV protease inhibitor, co-administered with low-dose ritonavir (800/100 mg once d
Autor:
Koen Iterbeke, Dirk Tourwé, Marion Kretzschmar, Bernd Johannsen, Jean Claude Reubi, Holm Wittrisch, Christoph Heichert, Kris Chavatte, Heike Rodig, Daniel Zips, Peter Mäding, Matthias Scheunemann, Ralf Bergmann
Publikováno v:
Nuclear Medicine and Biology. 29:61-72
4-([(18)F]fluoro)benzoyl-neurotensin(8-13) ((18)FB-Arg(8)-Arg(9)-Pro(10)-Tyr(11)- Ile(12)-Leu(13)-OH, 1) and two analogs stabilized in one and two positions ((18)FB-Arg(8)psi(CH(2)NH)Arg(9)-Pro(10)-Tyr(11)- Ile(12)-Leu(13)-OH, 2, (18)FB-Arg(8)psi(CH(
Autor:
Dirk Tourwé, Nathalie Carrel-Rémy, Peter Bläuenstein, P. August Schubiger, Koen Iterbeke, Peter Conrath, Martine Willmann, Lesley Allemann-Tannahill, Elisa García Garayoa
Publikováno v:
Nuclear Medicine and Biology. 28:75-84
The potential utility of neurotensin (NT) in cancer diagnosis and therapy is limited by its rapid degradation. New stabilized analogues were synthesized, labeled with [99mTc] and screened in vitro and in vivo. High affinity and rapid internalization
Autor:
Thomas N, Kakuda, Magda, Opsomer, Maarten, Timmers, Koen, Iterbeke, Tom, Van De Casteele, Vera, Hillewaert, Romana, Petrovic, Richard M W, Hoetelmans
Publikováno v:
Journal of clinical pharmacology. 54(8)
This study compared the bioavailability of two candidate fixed-dose combinations (FDCs: G003 and G004) of darunavir/cobicistat 800/150 mg with that of darunavir 800 mg and ritonavir 100 mg coadministered as single agents. Short-term safety and tolera
Autor:
J. Paris, S. Muller, Dirk Tourwé, H. Dumortier, Chantal Rabourdin-Combe, Koen Iterbeke, Marie-Claude Trescol-Biémont, J. R. Casimir, W. Van Den Nest, Denis Gerlier
Publikováno v:
The Journal of Peptide Research. 56:398-408
A series of conformationally restricted analogs of the hen egg lysozyme (HEL) decapeptide 52-61 in which the conformationally flexible Tyr53 residue was replaced by several more constrained tyrosine and phenylalanine analogs was prepared. Among these
Publikováno v:
The Journal of Organic Chemistry. 65:6487-6492
4-Amino-2-benzazepin-3-ones have proven very useful for studying the biologically active conformations of peptides. The synthesis of Pht-Aba-Xaa-OH by reaction of the corresponding 1,3-oxazolidin-5...
Publikováno v:
Letters in Peptide Science. 5:121-123
During a study on the preparation of the conformationally restricted analogue of tryptophan into 1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid 1 by a Pictet–Spengler condensation with formaldehyde, two side products were detected: N-hydroxymeth
A new Tc(I) radiolabeling method for peptides: Evaluation of neurotensin analogs for tumor targeting
Autor:
M. Willmann, A. Egli, N. Carrell-Rémy, Peter Bläuenstein, Roger Alberto, Peter Conrath, Pius A. Schubiger, Koen Iterbeke, Dirk Tourwé, L. Allemann
Publikováno v:
Peptides for the New Millennium ISBN: 0792364457
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ba8ed45b2291aef761d38a56a984e49
https://doi.org/10.1007/0-306-46881-6_317
https://doi.org/10.1007/0-306-46881-6_317