Fc galactosylation of anti-platelet human IgG1 alloantibodies enhances complement activation on platelets

Autor: Van Osch, TLJ, Oosterhoff, JJ, Bentlage, AEH, Nouta, J, Koeleman, CAM, Geerdes, DM, Mok, JY, Heidt, S, Mulder, A, Van, Esch WJE, Kapur, R, Porcelijn, L, Vidarsson, G

Approximately 20% of patients receiving multiple platelet transfusions develop platelet alloantibodies, which can be directed against human leukocyte antigens (HLA) and, to a lesser extent, against human platelet antigens (HPA). These antibodies can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______101::237f479dc5e85270f11e77484e27de9e
https://dspace.library.uu.nl/handle/1874/423183

The genetics and epidemiology of N- and O-immunoglobulin A glycomics.

Autor: Visconti A; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.; Center for Biostatistics, Epidemiology and Public Health, Department of Clinical and Biological Sciences, University of Turin, Turin, Italy., Rossi N; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Bondt A; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands., Ederveen AH; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands., Thareja G; Department of Biophysics and Physiology, Weill Cornell Medicine-Qatar, Doha, Qatar., Koeleman CAM; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands., Stephan N; Department of Biophysics and Physiology, Weill Cornell Medicine-Qatar, Doha, Qatar., Halama A; Department of Biophysics and Physiology, Weill Cornell Medicine-Qatar, Doha, Qatar., Lomax-Browne HJ; Centre for Inflammatory Disease, Department of Immunology and Inflammation, Imperial College London, London, UK., Pickering MC; Centre for Inflammatory Disease, Department of Immunology and Inflammation, Imperial College London, London, UK., Zhou XJ; Renal Division, Peking University First Hospital, Beijing, China.; Peking University Institute of Nephrology, Beijing, China.; Key Laboratory of Renal Disease, Ministry of Health of China, Beijing, China.; Key Laboratory of Chronic Kidney Disease Prevention and Treatment, Ministry of Education, Peking University, Beijing, China., Wuhrer M; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands., Suhre K; Department of Biophysics and Physiology, Weill Cornell Medicine-Qatar, Doha, Qatar., Falchi M; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK. mario.falchi@kcl.ac.uk.

Publikováno v: Genome medicine [Genome Med] 2024 Aug 09; Vol. 16 (1), pp. 96. Date of Electronic Publication: 2024 Aug 09.

Assessment of IgG-Fc glycosylation from individual RhD-specific B cell clones reveals regulation at clonal rather than clonotypic level.

Autor: de Graaf EL; Immunoglobulin Research Laboratory, Department of Experimental Immunohematology, Sanquin Research, Amsterdam, The Netherlands.; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands., Larsen MD; Immunoglobulin Research Laboratory, Department of Experimental Immunohematology, Sanquin Research, Amsterdam, The Netherlands.; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands., van der Bolt N; Immunoglobulin Research Laboratory, Department of Experimental Immunohematology, Sanquin Research, Amsterdam, The Netherlands.; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands., Visser R; Immunoglobulin Research Laboratory, Department of Experimental Immunohematology, Sanquin Research, Amsterdam, The Netherlands.; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands., Verhagen OJHM; Immunoglobulin Research Laboratory, Department of Experimental Immunohematology, Sanquin Research, Amsterdam, The Netherlands.; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Hipgrave Ederveen AL; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands., Koeleman CAM; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands., van der Schoot CE; Immunoglobulin Research Laboratory, Department of Experimental Immunohematology, Sanquin Research, Amsterdam, The Netherlands.; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Wuhrer M; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands., Vidarsson G; Immunoglobulin Research Laboratory, Department of Experimental Immunohematology, Sanquin Research, Amsterdam, The Netherlands.; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands.

Publikováno v: Immunology [Immunology] 2024 Mar; Vol. 171 (3), pp. 428-439. Date of Electronic Publication: 2023 Dec 14.

A photoaffinity glycan-labeling approach to investigate immunoglobulin glycan-binding partners.

Autor: Holborough-Kerkvliet MD; Department of Rheumatology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands., Mucignato G; Department of Rheumatology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands., Moons SJ; Department of Synthetic Organic Chemistry, Radboud University, Toernooiveld 1, Mercator III, 6525 ED, Nijmegen, The Netherlands., Psomiadou V; Department of Synthetic Organic Chemistry, Radboud University, Toernooiveld 1, Mercator III, 6525 ED, Nijmegen, The Netherlands., Konada RSR; Department of Biochemistry, University of Texas Southwestern, 5323 Harry Hines Boulevard, Dallas, TX 75390-09185, United States., Pedowitz NJ; Department of Chemistry, University of Southern California, Los Angeles, CA 90089, United States., Pratt MR; Department of Chemistry, University of Southern California, Los Angeles, CA 90089, United States., Kissel T; Department of Rheumatology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands., Koeleman CAM; Center for Proteomics and Metabolomics, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands., Tjokrodirijo RTN; Center for Proteomics and Metabolomics, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands., van Veelen PA; Center for Proteomics and Metabolomics, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands., Huizinga T; Department of Rheumatology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands., van Schie KAJ; Department of Rheumatology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands., Wuhrer M; Center for Proteomics and Metabolomics, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands., Kohler JJ; Department of Biochemistry, University of Texas Southwestern, 5323 Harry Hines Boulevard, Dallas, TX 75390-09185, United States., Bonger KM; Department of Synthetic Organic Chemistry, Radboud University, Heyendaalseweg 135, 6525 AJ, Nijmegen, The Netherlands., Boltje TJ; Department of Synthetic Organic Chemistry, Radboud University, Toernooiveld 1, Mercator III, 6525 ED, Nijmegen, The Netherlands., Toes REM; Department of Rheumatology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.

Publikováno v: Glycobiology [Glycobiology] 2023 Oct 29; Vol. 33 (9), pp. 732-744.

IgG Fab Glycans Hinder FcRn-Mediated Placental Transport.

Autor: Volkov M; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands., Brinkhaus M; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands., van Schie KA; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands., Bondt A; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, the Netherlands., Kissel T; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands., van der Kooi EJ; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands., Bentlage AEH; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands., Koeleman CAM; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, the Netherlands., de Taeye SW; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands., Derksen NI; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands., Dolhain RJEM; Department of Rheumatology, Erasmus University Medical Center, Rotterdam, the Netherlands; and., Braig-Scherer U; International Health Centre-Polikliniek Prins Willem, The Hague, the Netherlands., Huizinga TWJ; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands., Wuhrer M; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, the Netherlands., Toes REM; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands., Vidarsson G; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands., van der Woude D; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2023 Jan 15; Vol. 210 (2), pp. 158-167.