Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Kodeeswaran Parameshwaran"'
Autor:
Patrick M Kanju, Kodeeswaran Parameshwaran, Catrina Sims-Robinson, Subramaniam Uthayathas, Eleanor M Josephson, Nagalingam Rajakumar, Muralikrishnan Dhanasekaran, Vishnu Suppiramaniam
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31073 (2012)
Cholinergic depletion in the medial septum (MS) is associated with impaired hippocampal-dependent learning and memory. Here we investigated whether long term potentiation (LTP) and synaptic currents, mediated by alpha-amino-3-hydroxy-5-methyl-isoxazo
Externí odkaz:
https://doaj.org/article/eb3868c7b5334580befb5e89e6732831
Autor:
Kodeeswaran Parameshwaran, Mohammed Almaghrabi, Manoj Govindarajulu, Randall C. Clark, Muralikrishnan Dhanasekaran
Publikováno v:
Bioactives and Pharmacology of Medicinal Plants ISBN: 9781003281702
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a8ae30cc349aa0cf51ea5150ea156b5
https://doi.org/10.1201/9781003281702-33
https://doi.org/10.1201/9781003281702-33
Publikováno v:
Brain research bulletin. 176
Nicotine is a strong psychoactive and addictive compound found in tobacco. Use of nicotine in the form of smoking, vaping or other less common methods during pregnancy has been shown to be related to poor health conditions, including cognitive proble
Autor:
Subramaniam Uthaythas, Kodeeswaran Parameshwaran, Sindhu Ramesh, Senthilkumar S. Karuppagounder, Manoj Govindarajulu, Muralikrishnan Dhanasekaran
Publikováno v:
Neurochemistry International. 148:105066
Parkinson's disease (PD) is a progressive neurodegenerative disorder that affects more than 10 million people worldwide. Oxidative stress and mitochondrial dysfunction play a significant role in altering the homeostasis of energy production and free
Autor:
Kodeeswaran Parameshwaran, Satyanarayana R. Pondugula, Engy Abdel-Rahman, Mohammed Majrashi, Manal Ali Buabeid, Sindhu Ramesh, Rajesh Amin, Kariharan Thiruchelvan, Muralikrishnan Dhanasekaran, Manuj Ahuja, Vishnu Suppiramaniam
Publikováno v:
Life Sciences. 177:49-59
Aims Inflammation is considered to be one of the crucial pathological factors associated with the development of Alzheimer's disease, although supportive experimental evidence remains undiscovered. Therefore, the current study was carried out to bett
Autor:
Euitaek Yang, Kodeeswaran Parameshwaran, Izhar A. Khan, Ami Bhakta, Muralikrishnan Dhanasekaran, Kartheek Gavini
Publikováno v:
Life sciences. 205
Aims Cerebral atrophy resulting from neurodegeneration is highly prevalent in individuals with diabetes; however, the underlying mechanisms for diabetic neurodegeneration are not fully understood. Here we hypothesized that hyperglycemia induces molec
Autor:
Ajitan Viswaprakash, Thirumalini Vaithianathan, Nilmini Viswaprakash, Vishnu Suppiramaniam, Robert L. Judd, Kodeeswaran Parameshwaran
Publikováno v:
Journal of Neuroscience Research. 93:1442-1450
Type 1 diabetes is associated with cognitive dysfunction. Cognitive processing, particularly memory acquisition, depends on the regulated enhancement of expression and function of glutamate receptor subtypes in the hippocampus. Impairment of memory w
Autor:
Kodeeswaran Parameshwaran, Michael H. Irwin, Carl A. Pinkert, Kosta Steliou, Vishnu Suppiramaniam
Publikováno v:
Drug Development Research. 76:72-81
Preclinical Research Mitochondrial dysfunction is a key component of various aging-related pathologies of the brain that result in dementia. As such, it provides an important avenue in development of therapeutic interventions for a host of neurologic
Publikováno v:
Behavioural brain research. 335
Chronic stress in humans can result in multiple adverse psychiatric and neurobiological outcomes, including memory deficits. These adverse outcomes can be more severe if each episode of stress is very traumatic. When compared to acute or short term s
Autor:
Thiruchelvam Kariharan, Subramaniam Uthayathas, Subhrajit Bhattacharya, Kodeeswaran Parameshwaran, Manal Ali Buabeid, Vishnu Suppiramaniam, Muralikrishnan Dhanasekaran
Publikováno v:
Neurobiology of Learning and Memory. 106:102-111
Smoking during pregnancy is associated with long lasting, hippocampus dependent, cognitive deficits in children. The current study was performed to investigate the effect of prenatal nicotine exposure on excitatory synaptic physiology and cellular si