Zobrazeno 1 - 10
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pro vyhledávání: '"Kodangattil Sreekumar"'
Akademický článek
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Autor:
Juan Carlos Almagro, Francisco Hernandez-Guzman, Jinquan Luo, Raymond W. Sweet, Alexey Teplyakov, Kodangattil Sreekumar R, Gary L. Gilliland
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 82:1553-1562
To assess the state of the art in antibody 3D modeling, 11 unpublished high-resolution x-ray Fab crystal structures from diverse species and covering a wide range of antigen-binding site conformations were used as a benchmark to compare Fv models gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f5770eb8c1667893e1b31095ea78f95
https://doi.org/10.1002/prot.24567
https://doi.org/10.1002/prot.24567
Autor:
Robyn L. Stanfield, Raymond Sweet, Galina Obmolova, Jinquan Luo, Juan Carlos Almagro, Thomas J. Malia, Alexey Teplyakov, Kodangattil Sreekumar R, Gary L. Gilliland
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 82:1563-1582
To assess the state-of-the-art in antibody structure modeling, a blinded study was conducted. Eleven unpublished Fab crystal structures were used as a benchmark to compare Fv models generated by seven structure prediction methodologies. In the first
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbc176107698c5a987328cadb37c4fde
https://doi.org/10.1002/prot.24554
https://doi.org/10.1002/prot.24554
Akademický článek
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Publikováno v:
In Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies 2015:147-170
We review here new technologies impacting antibody discovery and optimization, specifically next-generation sequencing (NGS). This technology is providing the means to study whole natural and manmade repertoires under a variety of selection condition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::862aabf6e3fd5d13f1b9912b784cd551
https://doi.org/10.1016/b978-0-12-416603-5.00007-9
https://doi.org/10.1016/b978-0-12-416603-5.00007-9
The functional repertoire of rabbit antibodies and antibody discovery via next-generation sequencing
Autor:
Snehal Naik, Christine Huard, Juan Carlos Almagro, Kodangattil Sreekumar R, Huilan Gao, Santosh Hodawadekar, Jian Li, Cindy Ross, Alberto Visintin, Jessica Min-debartolo, Alessandro Mascioni
To gain insight into the functional antibody repertoire of rabbits, the VH and VL repertoires of bone marrow (BM) and spleen (SP) of a naive New Zealand White rabbit (NZW; Oryctolagus cuniculus) and that of lymphocytes collected from a NZW rabbit imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b152e658fa3b096130d5692e913eb0f
https://europepmc.org/articles/PMC4011907/
https://europepmc.org/articles/PMC4011907/
Autor:
Brett A. Barbaro, Andrea E. Prack, Peter A. Bullock, Kodangattil Sreekumar, Danielle R. Winters
Publikováno v:
Journal of Virology. 74:8601-8613
Initiation of DNA replication is a complicated and highly regulated process that takes place during the S phase of the cell cycle. Progress in understanding initiation events in eukaryotes includes the identification of many of the factors that catal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38a1d634f9859d061a15b7f5baa11cfe
https://doi.org/10.1128/jvi.74.18.8601-8613.2000
https://doi.org/10.1128/jvi.74.18.8601-8613.2000
Publikováno v:
Journal of Biological Chemistry. 274:9677-9685
Palmitoleate is not present in lipid A isolated from Escherichia coli grown at 30 °C or higher, but it comprises ∼11% of the fatty acyl chains of lipid A in cells grown at 12 °C. The appearance of palmitoleate at 12 °C is accompanied by a declin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb2d53e09c94b8f1635c1cfc07ad2131
https://doi.org/10.1074/jbc.274.14.9677
https://doi.org/10.1074/jbc.274.14.9677
Publikováno v:
Virology. 227:460-473
Replication initiation events are suppressed over the SV40 core origin in vitro; they are also greatly reduced over sequences flanking the origin which contain binding sites for several transcription factors. To address the biochemical basis for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::906d8623e73d625d8135128d563c02a0
https://doi.org/10.1006/viro.1996.8347
https://doi.org/10.1006/viro.1996.8347