Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kobporn Lulu Howell"'
Autor:
Stacy W. Remiszewski, Lidia C. Sambucetti, Kenneth W. Bair, John Bontempo, David Cesarz, Nagarajan Chandramouli, Ru Chen, Min Cheung, Susan Cornell-Kennon, Karl Dean, George Diamantidis, Dennis France, Michael A. Green, Kobporn Lulu Howell, Rina Kashi, Paul Kwon, Peter Lassota, Mary S. Martin, Yin Mou, Lawrence B. Perez, Sushil Sharma, Troy Smith, Eric Sorensen, Francis Taplin, Nancy Trogani, Richard Versace, Heather Walker, Susan Weltchek-Engler, Alexander Wood, Arthur Wu, Peter Atadja
Publikováno v:
Journal of Medicinal Chemistry. 46:4609-4624
A series of N-hydroxy-3-phenyl-2-propenamides were prepared as novel inhibitors of human histone deacetylase (HDAC). These compounds were potent enzyme inhibitors, having IC50s < 400 nM in a partially purified enzyme assay. However, potency in cell g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e0206bc14fdb324b1acbdd17eeea9cc
https://doi.org/10.1021/jm030235w
https://doi.org/10.1021/jm030235w
Autor:
Nancy Trogani, Paul Kwon, Kobporn Lulu Howell, Manfred Jung, Peter Wisdom Atadja, Kenneth W. Bair, Michael A. Green, Wendy D. Cornell, Heather Walker, Stacy W. Remiszewski, Lidia C. Sambucetti
Publikováno v:
Journal of Medicinal Chemistry. 45:753-757
Inhibitors of histone deacetylase (HDAC) have been shown to induce terminal differentiation of human tumor cell lines and to have antitumor effects in vivo. We have prepared analogues of suberoylanilide hydroxamic acid (SAHA) and trichostatin A and h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::283811b83c8f67cc2696870aa035615b
https://doi.org/10.1021/jm015568c
https://doi.org/10.1021/jm015568c
Autor:
Stacy W, Remiszewski, Lidia C, Sambucetti, Kenneth W, Bair, John, Bontempo, David, Cesarz, Nagarajan, Chandramouli, Ru, Chen, Min, Cheung, Susan, Cornell-Kennon, Karl, Dean, George, Diamantidis, Dennis, France, Michael A, Green, Kobporn Lulu, Howell, Rina, Kashi, Paul, Kwon, Peter, Lassota, Mary S, Martin, Yin, Mou, Lawrence B, Perez, Sushil, Sharma, Troy, Smith, Eric, Sorensen, Francis, Taplin, Nancy, Trogani, Richard, Versace, Heather, Walker, Susan, Weltchek-Engler, Alexander, Wood, Arthur, Wu, Peter, Atadja
Publikováno v:
Journal of medicinal chemistry. 46(21)
A series of N-hydroxy-3-phenyl-2-propenamides were prepared as novel inhibitors of human histone deacetylase (HDAC). These compounds were potent enzyme inhibitors, having IC(50)s400 nM in a partially purified enzyme assay. However, potency in cell gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bb53e5018b4b18dfee5bd9f0a811de98
https://pubmed.ncbi.nlm.nih.gov/14521422
https://pubmed.ncbi.nlm.nih.gov/14521422