Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Kobina Essandoh"'
Publikováno v:
Antioxidants, Vol 11, Iss 9, p 1822 (2022)
Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases regulate production of reactive oxygen species (ROS) that cause oxidative damage to cellular components but also regulate redox signaling in many cell types with essential functions in the
Externí odkaz:
https://doaj.org/article/02ef587cf7324ff8940e52eff5e9be26
Autor:
Shan Deng, Kobina Essandoh, Xiaohong Wang, Yutian Li, Wei Huang, Jing Chen, Jiangtong Peng, Ding-Sheng Jiang, Xingjiang Mu, Chenran Wang, Tianqing Peng, Jun-Lin Guan, Yigang Wang, Anil Jegga, Kai Huang, Guo-Chang Fan
Publikováno v:
Redox Biology, Vol 32, Iss , Pp - (2020)
Currently, most antioxidants do not show any favorable clinical outcomes in reducing myocardial ischemia-reperfusion (I/R) injury, suggesting an urgent need for exploring a new regulator of redox homeostasis in I/R hearts. Here, using heart-specific
Externí odkaz:
https://doaj.org/article/893b9c5b578444b1b628dba94023fa55
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Regulation of cardiac physiology is well known to occur through the action of kinases that reversibly phosphorylate ion channels, calcium handling machinery, and signaling effectors. However, it is becoming increasingly apparent that palmitoylation o
Externí odkaz:
https://doaj.org/article/9c85599cc56e4f50a68e0f03b4e4681a
Autor:
Kobina Essandoh, Shan Deng, Xiaohong Wang, Yutian Li, Qianqian Li, Xingjiang Mu, Tianqing Peng, Guo-Chang Fan
Publikováno v:
Cells, Vol 9, Iss 9, p 1936 (2020)
Cardiac cells can adapt to pathological stress-induced energy crisis by shifting from fatty acid oxidation to glycolysis. However, the use of glucose-insulin-potassium (GIK) solution in patients undergoing cardiac surgery does not alleviate ischemia/
Externí odkaz:
https://doaj.org/article/141dc8ae31a9453ea35073356d470bbf
Autor:
Lu Wang, Yutian Li, Xiaohong Wang, Peng Wang, Kobina Essandoh, Shunan Cui, Wei Huang, Xingjiang Mu, Zhenling Liu, Yigang Wang, Tianqing Peng, Guo-Chang Fan
Publikováno v:
Cells, Vol 9, Iss 1, p 120 (2020)
Macrophages are critical for regulation of inflammatory response during endotoxemia and septic shock. However, the mediators underlying their regulatory function remain obscure. Growth differentiation factor 3 (GDF3), a member of transforming growth
Externí odkaz:
https://doaj.org/article/f64a32f884bf42d088a89ebb5db19231
Autor:
Kobina Essandoh, Arasakumar Subramani, Olivia A. Ferro, James P. Teuber, Sribharat Koripella, Matthew J. Brody
Publikováno v:
JACC: Basic to Translational Science. 8:518-542
Publikováno v:
The Journal of Pathology. 256:249-252
Investigations of major mevalonate pathway enzymes have demonstrated the importance of local isoprenoid synthesis in cardiac homeostasis. Farnesyl diphosphate synthase (FPPS) synthesizes isoprenoid precursors needed for cholesterol biosynthesis and p
Publikováno v:
Circulation Research. 131
Palmitoylation is the reversible post-translational modification of proteins with fatty acids catalyzed by zDHHC S-acyltransferases that functions as a potent regulatory mechanism controlling protein trafficking and signal transduction. To investigat
Autor:
Kobina Essandoh, Arasakumar Subramani, James P. Teuber, Sribharat Koripella, Matthew J. Brody
Publikováno v:
Biophysical Journal. 122:517a
Autor:
Yutian Li, Qianqian Li, Peng Wang, Kobina Essandoh, Tianqing Peng, Guo-Chang Fan, Xiaohong Wang, Shan Deng, Hongyan Zhao, Xingjiang Mu
Publikováno v:
J Immunol
The inability to effectively control invading bacteria or other pathogens is a major cause of multiple organ dysfunction and death in sepsis. As the first-line defense of the immune system, macrophages play a crucial role in the removal of pathogens