Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation-induced tissue damage.

Autor: Rognoni E; Centre for Stem Cells and Regenerative Medicine, King's College London, Guy's Hospital, London, United Kingdom.; Centre for Endocrinology, William Harvey Research Institute, Barts and The London School of Medicine, Queen Mary University of London, London, United Kingdom., Goss G; Centre for Stem Cells and Regenerative Medicine, King's College London, Guy's Hospital, London, United Kingdom., Hiratsuka T; Centre for Stem Cells and Regenerative Medicine, King's College London, Guy's Hospital, London, United Kingdom.; Research Center for Dynamic Living Systems, Graduate School of Biostudies, Kyoto University, Kyoto, Japan., Sipilä KH; Centre for Stem Cells and Regenerative Medicine, King's College London, Guy's Hospital, London, United Kingdom., Kirk T; Centre for Endocrinology, William Harvey Research Institute, Barts and The London School of Medicine, Queen Mary University of London, London, United Kingdom., Kober KI; Division of Signaling and Functional Genomics, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Cell and Molecular Biology, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany., Lui PP; Centre for Stem Cells and Regenerative Medicine, King's College London, Guy's Hospital, London, United Kingdom., Tsang VS; Centre for Endocrinology, William Harvey Research Institute, Barts and The London School of Medicine, Queen Mary University of London, London, United Kingdom., Hawkshaw NJ; Division of Musculoskeletal and Dermatological Sciences, Faculty of Biology, Medicine and Health, School of Biological Sciences, Manchester Academic Health Science Centre, The University of Manchester and Salford Royal NHS Foundation Trust, Manchester, United Kingdom., Pilkington SM; Division of Musculoskeletal and Dermatological Sciences, Faculty of Biology, Medicine and Health, School of Biological Sciences, Manchester Academic Health Science Centre, The University of Manchester and Salford Royal NHS Foundation Trust, Manchester, United Kingdom., Cho I; Centre for Stem Cells and Regenerative Medicine, King's College London, Guy's Hospital, London, United Kingdom., Ali N; Centre for Stem Cells and Regenerative Medicine, King's College London, Guy's Hospital, London, United Kingdom.; The Francis Crick Institute, London, United Kingdom., Rhodes LE; Division of Musculoskeletal and Dermatological Sciences, Faculty of Biology, Medicine and Health, School of Biological Sciences, Manchester Academic Health Science Centre, The University of Manchester and Salford Royal NHS Foundation Trust, Manchester, United Kingdom., Watt FM; Centre for Stem Cells and Regenerative Medicine, King's College London, Guy's Hospital, London, United Kingdom.

Publikováno v: ELife [Elife] 2021 Dec 23; Vol. 10. Date of Electronic Publication: 2021 Dec 23.

Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability.

Autor: Pattabiraman DR; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA., Bierie B; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA., Kober KI; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA., Thiru P; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA., Krall JA; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA., Zill C; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA., Reinhardt F; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA., Tam WL; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA. Genome Institute of Singapore, 60 Biopolis Street, Singapore. Cancer Science Institute of Singapore, 14 Medical Drive, Singapore., Weinberg RA; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA. Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Ludwig Center for Molecular Oncology at MIT, Cambridge, MA 02142, USA. weinberg@wi.mit.edu.

Publikováno v: Science (New York, N.Y.) [Science] 2016 Mar 04; Vol. 351 (6277), pp. aad3680.