Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Ko Igami"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 1956-1965 (2021)
Principal component analysis (PCA) is a useful tool for omics analysis to identify underlying factors and visualize relationships between biomarkers. However, this approach is limited in addressing life complexity and further improvement is required.
Externí odkaz:
https://doaj.org/article/38238470e47247bab80a767633a4e84d
Autor:
Katsuhiko Sasaki, Kazuhito Gotoh, Sho Miake, Daiki Setoyama, Mikako Yagi, Ko Igami, Takeshi Uchiumi, Donchon Kang
Publikováno v:
EBioMedicine, Vol 20, Iss C, Pp 161-172 (2017)
Sepsis is a major cause of morbidity and mortality in seriously ill patients and mitochondrial dysfunction is associated with poor outcomes in septic patients. Although interleukin-6 (IL-6) is a good prognostic marker for sepsis, the relationship bet
Externí odkaz:
https://doaj.org/article/67e14ef3cd8b424cb629d03cffd8231d
Autor:
Kazuhito Gotoh, Takafumi Morisaki, Daiki Setoyama, Katsuhiko Sasaki, Mikako Yagi, Ko Igami, Soichi Mizuguchi, Takeshi Uchiumi, Yoshinori Fukui, Dongchon Kang
Publikováno v:
Cell Reports, Vol 25, Iss 7, Pp 1800-1815.e4 (2018)
Summary: Dendritic cell (DC) maturation induced by Toll-like receptor agonists requires activation of downstream signal transduction and metabolic changes. The endogenous metabolite citrate has recently emerged as a modulator of DC activation. Howeve
Externí odkaz:
https://doaj.org/article/6c1e87d4e40d4ffc823458723ec76953
Autor:
Ko Igami, Hiroki Kittaka, Mikako Yagi, Kazuhito Gotoh, Yuichi Matsushima, Tomomi Ide, Masataka Ikeda, Saori Ueda, Shin-Ichiro Nitta, Manami Hayakawa, Nakayama, Keiichi I., Masaki Matsumoto, Dongchon Kang, Takeshi Uchiumi
Publikováno v:
Life Science Alliance; Jul2024, Vol. 7 Issue 7, p1-15, 15p
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 1956-1965 (2021)
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 1956-1965 (2021)
Graphical abstract
Highlights • “Multiblock metabolomics” elucidates the global metabolic network in a whole body. • “Multiblock metabolomics” combines LC/MS-based metabolomics with multiblock PCA. • “Multiblock metabolomics” h
Highlights • “Multiblock metabolomics” elucidates the global metabolic network in a whole body. • “Multiblock metabolomics” combines LC/MS-based metabolomics with multiblock PCA. • “Multiblock metabolomics” h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81add9a8173efa684398bfcb0e88d68b
http://europepmc.org/articles/PMC8086023
http://europepmc.org/articles/PMC8086023
Autor:
Ko Igami, Takeshi Uchiumi, Masaki Shiota, Saori Ueda, Shigehiro Tsukahara, Masaru Akimoto, Masatoshi Eto, Dongchon Kang
Publikováno v:
Cancer science. 113(9)
Early detection and long-term monitoring are important for urothelial carcinoma of the bladder (UCB). Urine cytology and existing markers have insufficient diagnostic performance. Here, we examined medium-sized extracellular vesicles (EVs) in urine t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390c160368b5c0b40315da694594a461
https://pubmed.ncbi.nlm.nih.gov/35611462
https://pubmed.ncbi.nlm.nih.gov/35611462
Publikováno v:
Infection Control and Hospital Epidemiology
Infection Control & Hospital Epidemiology
Infection Control & Hospital Epidemiology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::093f6785177d490f7dc31cbbe1fe1f47
https://doi.org/10.1017/ice.2020.223
https://doi.org/10.1017/ice.2020.223
Publikováno v:
Cancer Research. 82:5104-5104
Purpose: Early detection and long-term monitoring are important for urothelial carcinoma of the bladder (UCB). Urine cytology and existing markers have insufficient diagnostic performance. Here, we used medium-sized extracellular vesicles (EVs) in ur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30af91ff4fd69c703e06e790b296da59
https://doi.org/10.1158/1538-7445.am2022-5104
https://doi.org/10.1158/1538-7445.am2022-5104
Autor:
Takeshi Uchiumi, Mikako Yagi, Yura Do, Ko Igami, Haruka Hirai, Takahiro Toshima, Katsuhiko Sasaki, Dongchon Kang, Kazuhito Gotoh
Publikováno v:
Bioscience Reports
Mitochondrial–nuclear communication, known as retrograde signaling, is important for regulating nuclear gene expression in response to mitochondrial dysfunction. Previously, we have found that p32/C1qbp-deficient mice, which have a mitochondrial tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c1bd5a6b91cdf13ca2d686c09fd76e8
http://europepmc.org/articles/PMC7685009
http://europepmc.org/articles/PMC7685009
Autor:
Mikako Yagi, Kazuhito Gotoh, Ko Igami, Sho Miake, Katsuhiko Sasaki, Dongchon Kang, Takeshi Uchiumi, Daiki Setoyama
Publikováno v:
EBioMedicine, Vol 20, Iss C, Pp 161-172 (2017)
EBioMedicine
EBioMedicine
Sepsis is a major cause of morbidity and mortality in seriously ill patients and mitochondrial dysfunction is associated with poor outcomes in septic patients. Although interleukin-6 (IL-6) is a good prognostic marker for sepsis, the relationship bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cbede8c10a871a5f4b72ffa08fd8b12
https://doi.org/10.1016/j.ebiom.2017.05.018
https://doi.org/10.1016/j.ebiom.2017.05.018