Zobrazeno 1 - 10
of 841
pro vyhledávání: '"Knuutila Sakari"'
Autor:
Mosakhani Neda, Guled Mohamed, Leen Gayle, Calabuig-Fariñas Silvia, Niini Tarja, Machado Isidro, Savola Suvi, Scotlandi Katia, López-Guerrero José, Llombart-Bosch Antonio, Knuutila Sakari
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 31, Iss 1, p 24 (2012)
Abstract Background Xenografts have been shown to provide a suitable source of tumor tissue for molecular analysis in the absence of primary tumor material. We utilized ES xenograft series for integrated microarray analyses to identify novel biomarke
Externí odkaz:
https://doaj.org/article/28ab55460a2c44f782b23bba54ee88cb
Autor:
Yamamoto Toshiyuki, Shimojima Keiko, Miikkulainen Taina, Sipponen Marjatta, Peippo Maarit, Siggberg Linda, Ignatius Jaakko, Knuutila Sakari
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 6, Iss 1, p 45 (2011)
Abstract Background Only 29 cases of constitutional 9q22 deletions have been published and all have been sporadic. Most associate with Gorlin syndrome or nevoid basal cell carcinoma syndrome (NBCCS, MIM #109400) due to haploinsufficiency of the PTCH1
Externí odkaz:
https://doaj.org/article/26b61af47f14432cac449a89a3eca188
Autor:
Knuutila Sakari, Ferreira José A, Scheinin Ilari, Meijer Gerrit A, van de Wiel Mark A, Ylstra Bauke
Publikováno v:
BMC Bioinformatics, Vol 11, Iss 1, p 331 (2010)
Abstract Background Determining a suitable sample size is an important step in the planning of microarray experiments. Increasing the number of arrays gives more statistical power, but adds to the total cost of the experiment. Several approaches for
Externí odkaz:
https://doaj.org/article/c76aef491ac64e73b11cad1b03881026
Autor:
Picci Piero, Serra Massimo, Niini Tarja, Tripathi Abhishek, Klami Arto, Savola Suvi, Kaski Samuel, Zambelli Diana, Scotlandi Katia, Knuutila Sakari
Publikováno v:
BMC Cancer, Vol 9, Iss 1, p 17 (2009)
Abstract Background Ewing sarcoma family of tumors (ESFT), characterized by t(11;22)(q24;q12), is one of the most common tumors of bone in children and young adults. In addition to EWS/FLI1 gene fusion, copy number changes are known to be significant
Externí odkaz:
https://doaj.org/article/a47243f78d57405696815722d3b1007d
Autor:
Saharinen Juha, Knuutila Sakari, Hollmén Jaakko, Sarhadi Virinder K, Puustinen Anne, Hienonen-Kempas Tuija, Ruosaari Salla, Wikman Harriet, Anttila Sisko
Publikováno v:
BMC Medical Genomics, Vol 1, Iss 1, p 55 (2008)
Abstract Background Studies on asbestos-induced tumourigenesis have indicated the role of, e.g., reactive oxygen/nitrogen species, mitochondria, as well as NF-κB and MAPK signalling pathways. The exact molecular mechanisms contributing to asbestos-m
Externí odkaz:
https://doaj.org/article/88364fffdaf84d8ab12f516bef09e9d4
Autor:
Knuutila Sakari, Borg Åke, Chebil Gunilla, Andersson Anna, Liedberg Fredrik, Aits Sonja, Jee Kowan, Gudjonsson Sigurdur, Lindgren David, Fioretos Thoas, Månsson Wiking, Höglund Mattias
Publikováno v:
BMC Cancer, Vol 8, Iss 1, p 183 (2008)
Abstract Background Urothelial carcinomas originate from the epithelial cells of the inner lining of the bladder and may appear as single or as multiple synchronous tumors. Patients with urothelial carcinomas frequently show recurrences after treatme
Externí odkaz:
https://doaj.org/article/6ece1d3125024fbfa183d987fe88c768
Publikováno v:
BMC Medical Genomics, Vol 1, Iss 1, p 15 (2008)
Abstract Background DNA amplifications alter gene dosage in cancer genomes by multiplying the gene copy number. Amplifications are quintessential in a considerable number of advanced cancers of various anatomical locations. The aims of this study wer
Externí odkaz:
https://doaj.org/article/646b782af5c84f808981314d39454ec2
Autor:
Kaski Samuel, Ruosaari Salla, Lahti Leo, Korpela Mikko V, Lindholm Pamela M, Nymark Penny, Hollmén Jaakko, Anttila Sisko, Kinnula Vuokko L, Knuutila Sakari
Publikováno v:
BMC Genomics, Vol 8, Iss 1, p 62 (2007)
Abstract Background Asbestos has been shown to cause chromosomal damage and DNA aberrations. Exposure to asbestos causes many lung diseases e.g. asbestosis, malignant mesothelioma, and lung cancer, but the disease-related processes are still largely
Externí odkaz:
https://doaj.org/article/74167783ca2a4de89aa1e2028c2e5fc6
Publikováno v:
In T{\"u}lay Adali, Jocelyn Chanussot, Christian Jutten, and Jan Larsen, editors, Proceedings of the 2009 IEEE International Workshop on Machine Learning for Signal Processing XIX, pages 89--94. IEEE, Piscataway, NJ, USA, 2009
Unsupervised two-view learning, or detection of dependencies between two paired data sets, is typically done by some variant of canonical correlation analysis (CCA). CCA searches for a linear projection for each view, such that the correlations betwe
Externí odkaz:
http://arxiv.org/abs/1101.5919
Autor:
Tanner, Stephan M., Austin, Jamie L., Leone, Gustavo, Rush, Laura J., Plass, Christoph, Heinonen, Kristiina, Mrózek, Krzysztof, Sill, Heinz, Knuutila, Sakari, Kolitz, Jonathan E., Archer, Kellie J., Caligiuri, Michael A., Bloomfield, Clara D., de la Chapelle, Albert
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2001 Nov . 98(24), 13901-13906.
Externí odkaz:
https://www.jstor.org/stable/3057192