Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Knut Sturmhoefel"'
Autor:
Ron L. Peterson, Andrew J. Dorner, Knut Sturmhoefel, Margot O'Toole, Stanley F. Wolf, Holly Swiniarski
Publikováno v:
Clinical Immunology. 94:200-211
The effect of in vivo administration of rmIL-12 on the CTL response to immunization with a weakly immunogenic class I-restricted peptide emulsified in incomplete Freund's adjuvant was investigated. In the absence of IL-12, peptide-specific CTL respon
Autor:
Knut Sturmhoefel, Stanley F. Wolf, Kwang Lee, Holly Swiniarski, Andrew J. Dorner, Margot O'Toole
Publikováno v:
Journal of Immunological Methods. 233:1-11
In this paper, we present a method for measuring antigen specific cytotoxic T lymphocyte (CTL) activity from individual mouse peripheral blood samples without animal sacrifice. Peripheral blood cells are stimulated in vitro with a cocktail of antigen
Autor:
Kwang Lee, Holly Swiniarski, Gary S. Gray, Andrew J. Dorner, Jenifer L. Thomas, Margot O'Toole, Knut Sturmhoefel, Stanley F. Wolf
Publikováno v:
Clinical Immunology. 92:235-245
The identification of both class I- and class II-restricted tumor-associated peptides recognized by T cells has led to the test of these peptides as immunogens in experimental immunotherapy for cancer patients. However, optimal T cell activation requ
Autor:
Patrick E. Fields, Rosalynde J. Finch, Gary S. Gray, Richard Zollner, Jenifer L. Thomas, Knut Sturmhoefel, Kwan Lee, Stanley Wolf, Thomas F. Gajewski, Frank W. Fitch
Publikováno v:
The Journal of Immunology. 161:5268-5275
Using a TCR transgenic mouse bred onto a recombinase-activating gene-2-deficient background, we have examined the influence of B7.1 and B7.2 on activation of naive, CD8+ T cells in vitro. We found that B7.1 was a more potent costimulus than B7.2 for
Autor:
Knut Sturmhoefel, Margot O'Toole, Kwang Lee, Stanley F. Wolf, Willem W. Overwijk, Andrew J. Dorner, Holly Swiniarski, Nicholas P. Restifo
Publikováno v:
Journal of interferoncytokine research : the official journal of the International Society for Interferon and Cytokine Research. 20(6)
Interleukin-12 (IL-12) has been shown to play a central role in the innate and acquired immune responses. Its activities include enhancement of natural killer (NK) and cytotoxic T lymphocyte (CTL) activity and promotion of CD4 Th1 cell development. I