Expanding the genetic toolbox for the obligate human pathogen Streptococcus pyogenes

Autor: Nina Lautenschläger, Katja Schmidt, Carolin Schiffer, Thomas F. Wulff, Karin Hahnke, Knut Finstermeier, Moïse Mansour, Alexander K. W. Elsholz, Emmanuelle Charpentier

Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)

Genetic tools form the basis for the study of molecular mechanisms. Despite many recent advances in the field of genetic engineering in bacteria, genetic toolsets remain scarce for non-model organisms, such as the obligatory human pathogen Streptococ

Externí odkaz: https://doaj.org/article/ab38edfc233547cf9549c6c011dab4ff

Alu elements in ANRIL non-coding RNA at chromosome 9p21 modulate atherogenic cell functions through trans-regulation of gene networks.

Autor: Lesca M Holdt, Steve Hoffmann, Kristina Sass, David Langenberger, Markus Scholz, Knut Krohn, Knut Finstermeier, Anika Stahringer, Wolfgang Wilfert, Frank Beutner, Stephan Gielen, Gerhard Schuler, Gabor Gäbel, Hendrik Bergert, Ingo Bechmann, Peter F Stadler, Joachim Thiery, Daniel Teupser

Publikováno v: PLoS Genetics, Vol 9, Iss 7, p e1003588 (2013)

The chromosome 9p21 (Chr9p21) locus of coronary artery disease has been identified in the first surge of genome-wide association and is the strongest genetic factor of atherosclerosis known today. Chr9p21 encodes the long non-coding RNA (ncRNA) antis

Externí odkaz: https://doaj.org/article/57a8bf2e5c2b4dc88a63d90a2d6631ab

CMV reactivation drives posttransplant T-cell reconstitution and results in defects in the underlying TCRβ repertoire

Autor: Harlan Robins, Amelia Langston, Audrey Grizzle, Jennifer Robertson, Jason A. Conger, Muna Qayed, John T. Horan, Bruce R. Blazar, Aneesh K. Mehta, Aneesah Garrett, J. Cheeseman, Knut Finstermeier, Edmund K. Waller, Divya Koura, Cindy Desmarais, Leslie S. Kean, Rithun Mukherjee, Hanna Jean Khoury, Benjamin Watkins, Linda Stempora, Allan D. Kirk, Yvonne Suessmuth

Publikováno v: Blood. 125:3835-3850

Although cytomegalovirus (CMV) reactivation has long been implicated in posttransplant immune dysfunction, the molecular mechanisms that drive this phenomenon remain undetermined. To address this, we combined multiparameter flow cytometric analysis a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d7f807de544f14c4a1d8659abeafa3b
https://doi.org/10.1182/blood-2015-03-631853

Species richness and distribution patterns of leaf-inhabiting endophytic fungi in a temperate forest canopy

Autor: Knut Finstermeier, Almut Reiher, Martin Unterseher, Wilfried Morawetz, Peter Otto

Publikováno v: Mycological Progress. 6:201-212

In 2005, researchers at the Leipzig Canopy Crane Research Facility collected living leaves of four temperate tree species at heights of between 15 and 33 m above the ground. Following surface sterilisation of the leaves, leaf-fragments were cultured

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d695f7037d2f269a5e043320ca1cda99
https://doi.org/10.1007/s11557-007-0541-1

Next-Generation Museomics Disentangles One of the Largest Primate Radiations

Autor: Vincent Savolainen, Knut Finstermeier, Katerina Guschanski, Johannes Krause, Zoltán T. Nagy, Frieder Mayer, Gontran Sonet, Susanna Sawyer, Richard Sabin, Georges Lenglet, Sebastian Bailey, Luis M. Valente, Emmanuel Gilissen

Publikováno v: Guschanski, K, Krause, J, Sawyer, S, Valente, L M, Bailey, S, Finstermeier, K, Sabin, R, Gilissen, E, Sonet, G, Nagy, Z T, Lenglet, G, Mayer, F & Savolainen, V 2013, ' Next-generation museomics disentangles one of the largest primate radiations ', Systematic biology, vol. 62, no. 4, pp. 539-554 . https://doi.org/10.1093/sysbio/syt018
Systematic Biology

Guenons (tribe Cercopithecini) are one of the most diverse groups of primates. They occupy all of sub-Saharan Africa and show great variation in ecology, behavior, and morphology. This variation led to the description of over 60 species and subspecie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::977842ef4cb84ac5f1a87a79dbe6e5af
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-348953