Výsledky vyhledávání - "Knowlton Nicholas"

Akademický článek

Disease-associated pathophysiologic structures in pediatric rheumatic diseases show characteristics of scale-free networks seen in physiologic systems: implications for pathogenesis and treatment

Autor: McGhee Timothy, Chaser Brad, McKee Ryan, Chen Yanmin, Jiang Kaiyu, Knowlton Nicholas, Aggarwal Amita, Wang Shirley, Frank Mark, Osban Jeanette, Jarvis James N

Publikováno v: BMC Medical Genomics, Vol 2, Iss 1, p 9 (2009)

Abstract Background While standard reductionist approaches have provided some insights into specific gene polymorphisms and molecular pathways involved in disease pathogenesis, our understanding of complex traits such as atherosclerosis or type 2 dia

Externí odkaz: https://doaj.org/article/546d7a458e6d40b189f603f0fbb2d505

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Akademický článek

Discriminators of mouse bladder response to intravesical Bacillus Calmette-Guerin (BCG)

Autor: Centola Michael, Frank Mark, Knowlton Nicholas, Wallis Gemma, Davis Carole, Simpson Cindy, Saban Marcia R, Gallucci Randle M, Saban Ricardo

Publikováno v: BMC Immunology, Vol 8, Iss 1, p 6 (2007)

Abstract Background Intravesical Bacillus Calmette-Guerin (BCG) is an effective treatment for bladder superficial carcinoma and it is being tested in interstitial cystitis patients, but its precise mechanism of action remains poorly understood. It is

Externí odkaz: https://doaj.org/article/3722e1cdf3334014bedd48acfe477e43

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Akademický článek

Analysis of the interaction of extracellular matrix and phenotype of bladder cancer cells

Autor: Dozmorov Igor, Knowlton Nicholas, Saban Ricardo, Kyker Kimberly D, Dozmorov Mikhail G, Centola Michael B, Hurst Robert E

Publikováno v: BMC Cancer, Vol 6, Iss 1, p 12 (2006)

Abstract Background The extracellular matrix has a major effect upon the malignant properties of bladder cancer cells both in vitro in 3-dimensional culture and in vivo. Comparing gene expression of several bladder cancer cells lines grown under perm

Externí odkaz: https://doaj.org/article/da4d4ecb5dd2458c8acb60cd2d4160f2

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Akademický článek

Statistical monitoring of weak spots for improvement of normalization and ratio estimates in microarrays

Autor: Tang Yuhong, Knowlton Nicholas, Dozmorov Igor, Centola Michael

Publikováno v: BMC Bioinformatics, Vol 5, Iss 1, p 53 (2004)

Abstract Background Several aspects of microarray data analysis are dependent on identification of genes expressed at or near the limits of detection. For example, regression-based normalization methods rely on the premise that most genes in compared

Externí odkaz: https://doaj.org/article/2babd2450ff840bc998a10fd67ddea42

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