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A comparison of antiasthma drugs between acute and chronic ovalbumin-challenged guinea-pig models of asthma

Autor: Evans, Rhys L., Nials, Anthony T., Knowles, Richard G., Kidd, Emma J., Ford, William R., Broadley, Kenneth J.

Publikováno v: In Pulmonary Pharmacology & Therapeutics December 2012 25(6):453-464

Plasma proteins elevated in severe asthma despite oral steroid use and unrelated to Type-2 inflammation

Autor: Sparreman Mikus, Maria, Kolmert, Johan, Andersson, Lars I, ��stling, J��rgen, Knowles, Richard G, G��mez, Cristina, Ericsson, Magnus, Th��rngren, John-Olof, Emami Khoonsari, Payam, Dahl��n, Barbro, Kupczyk, Maciej, De Meulder, Bertrand, Auffray, Charles, Bakke, Per S, Beghe, Bianca, Bel, Elisabeth H, Caruso, Massimo, Chanez, Pascal, Chawes, Bo, Fowler, Stephen J, Gaga, Mina, Geiser, Thomas, Gjomarkaj, Mark, Horv��th, Ildik��, Howarth, Peter H, Johnston, Sebastian L, Joos, Guy, Krug, Norbert, Montuschi, Paolo, Musial, Jacek, Ni��ankowska-Mogilnicka, Ewa, Olsson, Henric K, Papi, Alberto, Rabe, Klaus F, Sandstr��m, Thomas, Shaw, Dominick E, Siafakas, Nikolaos M, Uhl��n, Mathias, Riley, John H, Bates, Stewart, Middelveld, Roelinde J M, Wheelock, Craig E, Chung, Kian Fan, Adcock, Ian M, Sterk, Peter J, Djukanovic, Ratko, Nilsson, Peter, Dahl��n, Sven-Erik, James, Anna

Publikováno v: European respiratory journal, 59(2):2100142. European Respiratory Society
Sparreman Mikus, Maria; Kolmert, Johan; Andersson, Lars I; Östling, Jörgen; Knowles, Richard G; Gómez, Cristina; Ericsson, Magnus; Thörngren, John-Olof; Emami Khoonsari, Payam; Dahlén, Barbro; Kupczyk, Maciej; De Meulder, Bertrand; Auffray, Charles; Bakke, Per S; Beghe, Bianca; Bel, Elisabeth H; Caruso, Massimo; Chanez, Pascal; Chawes, Bo; Fowler, Stephen J; ... (2022). Plasma proteins elevated in severe asthma despite oral steroid use and unrelated to Type-2 inflammation. The European respiratory journal, 59(2) European Respiratory Society 10.1183/13993003.00142-2021
European Respiratory Journal
European Respiratory Journal, 2022, 59 (2), pp.2100142. ⟨10.1183/13993003.00142-2021⟩

Rationale: Asthma phenotyping requires novel biomarker discovery.Objectives: To identify plasma biomarkers associated with asthma phenotypes by application of a new proteomic panel to samples from two well-characterised cohorts of severe (SA) and mil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c763b5279b848ea01d289d15daf44407
http://hdl.handle.net/10044/1/101722

Formation of Nitric Oxide from L-Arginine in the Central Nervous System: A Transduction Mechanism for Stimulation of the Soluble Guanylate Cyclase

Autor: Knowles, Richard G., Palacios, Miriam, Moncada, Salvador

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 1989 Jul 01. 86(13), 5159-5162.

Externí odkaz: https://www.jstor.org/stable/34066

Urinary Leukotriene E4 and Prostaglandin D2 Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type-2 Inflammation

Autor: Kolmert, Johan, Balgoma, David, Bood, Johan, Konradsen, Jon R., Ericsson, Magnus, James, Anna, Mikus, Maria, Sousa, Ana R., Riley, John H., Bates, Stewart, Bakke, Per S., Pandis, Ioannis, Caruso, Massimo, Chanez, Pascal, Fowler, Stephen J., Geiser, Thomas, Howarth, Peter, Krug, Norbert, Montuschi, Paolo, Sanak, Marek, Behndig, Annelie, Shaw, Dominick E, Knowles, Richard G., Alving, Kjell, Hedlin, Gunilla, Chung, Kian Fan, Adcock, Ian M., Sterk, Peter J., Djukanovic, Ratko, Wheelock, Craig E., U-BIOPRED Study Group

Rationale: New approaches are needed to guide personalized treatment of asthma.Objective: To test if urinary eicosanoid metabolites can direct asthma phenotyping.Methods: Urinary metabolites of prostaglandins (PG), cysteinyl-leukotrienes (LT) and iso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::b30b83f13afe5b1721c79fbdc5b6303e