Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Knight Jrp"'
Autor:
Owen J. Sansom, von der Haar T, Giovanna R. Mallucci, William J. Faller, Christopher G. Proud, Knight Jrp, Anne E. Willis, Smales Cm, Rachel A. Ridgway, Nikola Vlahov
Increased protein synthesis supports the rapid proliferation associated with cancer. The Rpl24Bst mutant mouse reduces the expression of the ribosomal protein RPL24 and has been used to suppress translation and limit tumorigenesis in multiple mouse m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6b707fa323c5e9affc2a7f6e53ab9b1
https://doi.org/10.1101/2021.05.05.442715
https://doi.org/10.1101/2021.05.05.442715
Autor:
Chatterjee S; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast BT7 9AE, UK., Naeli P; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast BT7 9AE, UK., Onar O; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast BT7 9AE, UK.; Department of Biology, Faculty of Science, Ankara University, Ankara, Turkey., Simms N; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9NT, UK., Garzia A; Laboratory of RNA Molecular Biology, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA., Hackett A; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast BT7 9AE, UK., Coyle K; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast BT7 9AE, UK., Harris Snell P; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast BT7 9AE, UK., McGirr T; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast BT7 9AE, UK., Sawant TN; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast BT7 9AE, UK., Dang K; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9NT, UK., Stoichkova ZV; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9NT, UK., Azam Y; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast BT7 9AE, UK., Saunders MP; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9NT, UK., Braun M; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9NT, UK., Alain T; Children's Hospital of Eastern Ontario Research Institute, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ONK1H 8L1, Canada., Tuschl T; Laboratory of RNA Molecular Biology, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA., McDade SS; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast BT7 9AE, UK., Longley DB; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast BT7 9AE, UK., Gkogkas CG; Biomedical Research Institute, Foundation for Research and Technology-Hellas, University Campus, 45110 Ioannina, Greece., Adrain C; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast BT7 9AE, UK., Knight JRP; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9NT, UK., Jafarnejad SM; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast BT7 9AE, UK.
Publikováno v:
Nucleic acids research [Nucleic Acids Res] 2024 Nov 11; Vol. 52 (20), pp. 12534-12548.
Autor:
Liko D; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Mitchell L; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Campbell KJ; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Ridgway RA; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Jones C; MRC Toxicology Unit, Hodgkin Building Lancaster Road, Leicester, LE1 9HN, UK., Dudek K; MRC Toxicology Unit, Hodgkin Building Lancaster Road, Leicester, LE1 9HN, UK., King A; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Bryson S; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Stevenson D; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Blyth K; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1BD, UK., Strathdee D; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Morton JP; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1BD, UK., Bird TG; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Knight JRP; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK. john.knight@manchester.ac.uk., Willis AE; MRC Toxicology Unit, Hodgkin Building Lancaster Road, Leicester, LE1 9HN, UK., Sansom OJ; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK. o.sansom@beatson.gla.ac.uk.; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1BD, UK. o.sansom@beatson.gla.ac.uk.
Publikováno v:
Cell death and differentiation [Cell Death Differ] 2024 Sep; Vol. 31 (9), pp. 1235-1237.
Autor:
Roobol A, Roobol J, Carden MJ, Smith ME, Hershey JWB, Bastide A, Knight JRP, Willis AE, Smales CM
Publikováno v:
The Biochemical journal [Biochem J] 2024 Jun 19; Vol. 481 (12), pp. 777.
Autor:
Knight JRP; Beatson Institute, Cancer Research UK, Glasgow, United Kingdom; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom., Proud CG; Lifelong Health, South Australian Health and Medical Research Institute, Adelaide, Australia; Department of Biological Sciences, University of Adelaide, Adelaide, Australia., Mallucci G; UK Dementia Research Institute at The University of Cambridge, Cambridge, United Kingdom; Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom., von der Haar T; School of Biosciences, University of Kent, Canterbury, United Kingdom., Smales CM; School of Biosciences, University of Kent, Canterbury, United Kingdom., Willis AE; MRC Toxicology Unit, University of Cambridge, Cambridge, United Kingdom., Sansom OJ; Beatson Institute, Cancer Research UK, Glasgow, United Kingdom; Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom. Electronic address: o.sansom@beatson.gla.ac.uk.
Publikováno v:
The Journal of investigative dermatology [J Invest Dermatol] 2022 Dec; Vol. 142 (12), pp. 3346-3348.e1. Date of Electronic Publication: 2022 Jul 16.
Autor:
Knight JRP; CRUK Beatson Institute, Glasgow, United Kingdom., Alexandrou C; CRUK Beatson Institute, Glasgow, United Kingdom., Skalka GL; CRUK Beatson Institute, Glasgow, United Kingdom.; MRC Toxicology Unit, University of Cambridge, Cambridge, United Kingdom., Vlahov N; CRUK Beatson Institute, Glasgow, United Kingdom., Pennel K; Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Officer L; MRC Toxicology Unit, University of Cambridge, Cambridge, United Kingdom., Teodosio A; MRC Toxicology Unit, University of Cambridge, Cambridge, United Kingdom., Kanellos G; CRUK Beatson Institute, Glasgow, United Kingdom., Gay DM; CRUK Beatson Institute, Glasgow, United Kingdom.; Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., May-Wilson S; CRUK Beatson Institute, Glasgow, United Kingdom., Smith EM; CRUK Beatson Institute, Glasgow, United Kingdom., Najumudeen AK; CRUK Beatson Institute, Glasgow, United Kingdom., Gilroy K; CRUK Beatson Institute, Glasgow, United Kingdom., Ridgway RA; CRUK Beatson Institute, Glasgow, United Kingdom., Flanagan DJ; CRUK Beatson Institute, Glasgow, United Kingdom., Smith RCL; CRUK Beatson Institute, Glasgow, United Kingdom.; Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., McDonald L; Drug Discovery Unit, CRUK Beatson Institute, Glasgow, United Kingdom., MacKay C; Drug Discovery Unit, CRUK Beatson Institute, Glasgow, United Kingdom., Cheasty A; CRUK Therapeutic Discovery Laboratories, Jonas Webb Building, Babraham Research Campus, Cambridge, United Kingdom., McArthur K; CRUK Therapeutic Discovery Laboratories, Jonas Webb Building, Babraham Research Campus, Cambridge, United Kingdom., Stanway E; CRUK Therapeutic Discovery Laboratories, Jonas Webb Building, Babraham Research Campus, Cambridge, United Kingdom., Leach JD; CRUK Beatson Institute, Glasgow, United Kingdom.; Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Jackstadt R; CRUK Beatson Institute, Glasgow, United Kingdom., Waldron JA; CRUK Beatson Institute, Glasgow, United Kingdom., Campbell AD; CRUK Beatson Institute, Glasgow, United Kingdom., Vlachogiannis G; Division of Molecular Pathology, The Institute of Cancer Research, London, United Kingdom., Valeri N; Division of Molecular Pathology, The Institute of Cancer Research, London, United Kingdom.; Department of Medicine, The Royal Marsden NHS Foundation Trust, London, United Kingdom., Haigis KM; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts., Sonenberg N; Department of Biochemistry and Goodman Cancer Research Center, McGill University, Montreal, Quebec, Canada., Proud CG; Lifelong Health, South Australian Health and Medical Research Institute, North Terrace, Adelaide, South Australia, Australia.; Department of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia., Jones NP; CRUK Therapeutic Discovery Laboratories, Jonas Webb Building, Babraham Research Campus, Cambridge, United Kingdom., Swarbrick ME; CRUK Therapeutic Discovery Laboratories, Jonas Webb Building, Babraham Research Campus, Cambridge, United Kingdom., McKinnon HJ; Drug Discovery Unit, CRUK Beatson Institute, Glasgow, United Kingdom., Faller WJ; CRUK Beatson Institute, Glasgow, United Kingdom., Le Quesne J; MRC Toxicology Unit, University of Cambridge, Cambridge, United Kingdom.; Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom.; Leicester Cancer Research Centre, University of Leicester, Leicester, United Kingdom.; Glenfield Hospital, Leicester University Hospitals NHS Trust, Leicester, United Kingdom., Edwards J; Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Willis AE; MRC Toxicology Unit, University of Cambridge, Cambridge, United Kingdom., Bushell M; CRUK Beatson Institute, Glasgow, United Kingdom.; Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Sansom OJ; CRUK Beatson Institute, Glasgow, United Kingdom. o.sansom@beatson.gla.ac.uk.; Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom.
Publikováno v:
Cancer discovery [Cancer Discov] 2021 May; Vol. 11 (5), pp. 1228-1247. Date of Electronic Publication: 2020 Dec 16.
Autor:
Knight JRP; CRUK Beatson Institute, University of Glasgow, Glasgow, UK., Sansom OJ; CRUK Beatson Institute, University of Glasgow, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, UK.
Publikováno v:
Molecular & cellular oncology [Mol Cell Oncol] 2021 Feb 22; Vol. 8 (2), pp. 1884034. Date of Electronic Publication: 2021 Feb 22.
Autor:
Smith RCL; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, G61 1QH, UK., Kanellos G; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK., Vlahov N; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK., Alexandrou C; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK., Willis AE; MRC Toxicology Unit, University of Cambridge, Cambridge CB2 1QW, UK., Knight JRP; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK j.knight@beatson.gla.ac.uk., Sansom OJ; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, G61 1QH, UK.
Publikováno v:
Journal of cell science [J Cell Sci] 2021 Jan 13; Vol. 134 (1). Date of Electronic Publication: 2021 Jan 13.
The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer.
Autor:
Najumudeen AK; Cancer Research UK Beatson Institute, Glasgow, UK., Ceteci F; Cancer Research UK Beatson Institute, Glasgow, UK.; Georg Speyer Haus Institute for Tumour Biology and Experimental Therapy, Paul-Ehrlich-Straße, Frankfurt, Germany., Fey SK; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Hamm G; Imaging and data Analytics, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Cambridge, UK., Steven RT; National Physical Laboratory, Teddington, Middlesex, UK., Hall H; Cancer Research UK Beatson Institute, Glasgow, UK., Nikula CJ; National Physical Laboratory, Teddington, Middlesex, UK., Dexter A; National Physical Laboratory, Teddington, Middlesex, UK., Murta T; National Physical Laboratory, Teddington, Middlesex, UK., Race AM; Imaging and data Analytics, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Cambridge, UK.; Institute of Medical Bioinformatics and Biostatistics, University of Marburg, Marburg, Germany., Sumpton D; Cancer Research UK Beatson Institute, Glasgow, UK., Vlahov N; Cancer Research UK Beatson Institute, Glasgow, UK., Gay DM; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.; Københavns Universitet, BRIC, Copenhagen, Denmark., Knight JRP; Cancer Research UK Beatson Institute, Glasgow, UK., Jackstadt R; Cancer Research UK Beatson Institute, Glasgow, UK.; Heidelberg Institute for Stem Cell Technology and Experimental Medicine gGmbH (HI-STEM), Division of Cancer Progression and Metastasis, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany., Leach JDG; Cancer Research UK Beatson Institute, Glasgow, UK., Ridgway RA; Cancer Research UK Beatson Institute, Glasgow, UK., Johnson ER; Cancer Research UK Beatson Institute, Glasgow, UK., Nixon C; Cancer Research UK Beatson Institute, Glasgow, UK., Hedley A; Cancer Research UK Beatson Institute, Glasgow, UK., Gilroy K; Cancer Research UK Beatson Institute, Glasgow, UK., Clark W; Cancer Research UK Beatson Institute, Glasgow, UK., Malla SB; The Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., Dunne PD; The Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK., Rodriguez-Blanco G; Cancer Research UK Beatson Institute, Glasgow, UK., Critchlow SE; Bioscience, Oncology R&D, AstraZeneca, Cambridge, UK., Mrowinska A; Cancer Research UK Beatson Institute, Glasgow, UK., Malviya G; Cancer Research UK Beatson Institute, Glasgow, UK., Solovyev D; Cancer Research UK Beatson Institute, Glasgow, UK., Brown G; Cancer Research UK Beatson Institute, Glasgow, UK., Lewis DY; Cancer Research UK Beatson Institute, Glasgow, UK., Mackay GM; Cancer Research UK Beatson Institute, Glasgow, UK., Strathdee D; Cancer Research UK Beatson Institute, Glasgow, UK., Tardito S; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Gottlieb E; Cancer Research UK Beatson Institute, Glasgow, UK.; The Ruth and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel., Takats Z; Department of Metabolism, Imperial College London, London, UK., Barry ST; Bioscience, Oncology R&D, AstraZeneca, Cambridge, UK., Goodwin RJA; Imaging and data Analytics, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Cambridge, UK.; Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Bunch J; National Physical Laboratory, Teddington, Middlesex, UK., Bushell M; Cancer Research UK Beatson Institute, Glasgow, UK., Campbell AD; Cancer Research UK Beatson Institute, Glasgow, UK., Sansom OJ; Cancer Research UK Beatson Institute, Glasgow, UK. o.sansom@beatson.gla.ac.uk.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK. o.sansom@beatson.gla.ac.uk.
Publikováno v:
Nature genetics [Nat Genet] 2021 Jan; Vol. 53 (1), pp. 16-26. Date of Electronic Publication: 2021 Jan 07.
Autor:
Knight JRP; Beatson Institute for Cancer Research, Glasgow G61 1BD, UK., Garland G; MRC Toxicology Unit, University of Cambridge, Lancaster Road, Leicester LE1 9HN, UK., Pöyry T; MRC Toxicology Unit, University of Cambridge, Lancaster Road, Leicester LE1 9HN, UK., Mead E; School of Biosciences, University of Kent, Canterbury, Kent CT2 7NJ, UK., Vlahov N; Beatson Institute for Cancer Research, Glasgow G61 1BD, UK., Sfakianos A; MRC Toxicology Unit, University of Cambridge, Lancaster Road, Leicester LE1 9HN, UK., Grosso S; MRC Toxicology Unit, University of Cambridge, Lancaster Road, Leicester LE1 9HN, UK., De-Lima-Hedayioglu F; School of Biosciences, University of Kent, Canterbury, Kent CT2 7NJ, UK., Mallucci GR; UK Dementia Research Institute at the University of Cambridge and Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0XY, UK., von der Haar T; School of Biosciences, University of Kent, Canterbury, Kent CT2 7NJ, UK., Smales CM; School of Biosciences, University of Kent, Canterbury, Kent CT2 7NJ, UK., Sansom OJ; Beatson Institute for Cancer Research, Glasgow G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK., Willis AE; MRC Toxicology Unit, University of Cambridge, Lancaster Road, Leicester LE1 9HN, UK aew80@mrc-tox.cam.ac.uk.
Publikováno v:
Disease models & mechanisms [Dis Model Mech] 2020 Mar 26; Vol. 13 (3). Date of Electronic Publication: 2020 Mar 26.