Zobrazeno 1 - 10
of 329
pro vyhledávání: '"Kniess T"'
Publikováno v:
61. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, 19.-22.04.2023, Leipzig, Deutschland
Ziel: Die Herstellung von 6-L-[18F]FDOPA durch elektrophile Radiomarkierung mit [18F]F2 Gas ist eine in Dresden-Rossendorf seit über 20 Jahren praktizierte Methode [1,2]. Mit der Inbetriebnahme eines neuen Zyklotrons TR-Flex und des F2-Gastargets 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f5ffde59e71390725b7cb1c59da79f8
https://doi.org/10.1055/s-0043-1766340
https://doi.org/10.1055/s-0043-1766340
Publikováno v:
18th Workshop on Targetry and Target Chemistry, 21.-26.08.2022, Whistler, Canada
For the cyclotron-based production of the theranostic radionuclide 67Cu through the 70Zn(p,α)67Cu reaction electroplated metallic Zn and ZnO powder targets are being studied. Highly enriched 70Zn targets were designed and optimized considering nucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______4577::4935f897d4cb7c6faa377140055749e2
https://www.hzdr.de/publications/Publ-36329-1
https://www.hzdr.de/publications/Publ-36329-1
Publikováno v:
20th European Symposium on Radiopharmacy and Radiopharmaceuticals, 24.-27.11.2022, Verona, Italien
Abstracts from the 20th European symposium on radiopharmacy and radiopharmaceuticals, 24.-27.11.2022, Verona, ItalienEJNMMI Radiopharmacy and Chemistry
Abstracts from the 20th European symposium on radiopharmacy and radiopharmaceuticals, 24.-27.11.2022, Verona, ItalienEJNMMI Radiopharmacy and Chemistry
L-[11C]Methionine ([11C]Met) is frequently used for the diagnosis of tumours located in brain, head and neck or for tumours induced by the multiple myeloma. The radio synthesis of [11C]Met commonly starts with [11C]CO2 with subsequent transformation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4750baf217135972bc1736b882cddb08
https://www.hzdr.de/publications/Publ-34888-1
https://www.hzdr.de/publications/Publ-34888-1
Publikováno v:
Fourth international edition of the symposium on Technetium and Other Radiometals in Chemistry and Medicine (TERACHEM 2022), 14.-17.09.2022, Brixen, Italien
This project aims to explore the cyclotron-based production of 67Cu through the 70Zn(p,α)67Cu reaction, in contrast to other possible routes (e.g. photonuclear reaction). The reaction features a low yield and the need of expensive target material, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a61a10b9b17663ded2a078438b0c9e0
https://doi.org/10.1016/s0969-8051(22)02175-8
https://doi.org/10.1016/s0969-8051(22)02175-8
Akademický článek
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Publikováno v:
Annual Congress of the European Association of Nuclear Medicine, 20.-23.10.2021, Virtuell, Österreich
Aim/Introduction: In recent years quinoline-based small molecules targeting the fibroblast activation protein alpha (FAP) have gained interest for imaging a variety of tumor entities (1). A number of radiotracers for SPECT and PET have been developed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______4577::1f1104066b3af871827bb0f0638a9c90
https://www.hzdr.de/publications/Publ-32835-1
https://www.hzdr.de/publications/Publ-32835-1
Autor:
Laube, M., Gassner, C., Neuber, C., Wodtke, R., Ullrich, M., Haase-Kohn, C., Löser, R., Köckerling, M., Kopka, K., Knieß, T., Hey-Hawkins, E., Pietzsch, J.
Publikováno v:
RSC Advances 10(2020), 38601-38611
The inducible isoenzyme cyclooxygenase-2 (COX-2) is closely associated with chemo-/radioresistance and poor prognosis of solid tumors. Therefore, COX-2 represents an attractive target for functional characterization of tumors by positron emission tom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______4577::ce7ecc306955486bec5c7109dd81ae79
https://www.hzdr.de/publications/Publ-31056-1
https://www.hzdr.de/publications/Publ-31056-1
Publikováno v:
Journal of Medicinal Chemistry 62(2019), 6525-6539
When using selective estrogen receptor modulators (SERMs) in cancer therapy adverse effects such as endothelial dysfunction have to be considered. Estrogens and, consequently, SERMs regulate the synthesis of vasoactive nitric oxide (•NO). We hypoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______4577::54df9746ca0aa99d61f6c7726199516b
https://www.hzdr.de/publications/Publ-29248-1
https://www.hzdr.de/publications/Publ-29248-1
Autor:
Roscales, S., Kniess, T.
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals 62(2019), 393-403
4-[18F]Fluoro-N-hydroxybenzimidoyl chloride (18FHBIC) was developed as an 18F-labelled aromatic nitrile oxide precursor. The building block is obtained in a one-pot synthesis in up to 79% radiochemical yield starting from [18F]fluoride in 50 min with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______4577::078b6a9f8ee1d0e3de01df5bda83e66a
https://www.hzdr.de/publications/Publ-27816-1
https://www.hzdr.de/publications/Publ-27816-1
Publikováno v:
Methods in Molecular Biology 1929(2019), 461-485
The interaction of S100 proteins (S100s), a multigenic family of Ca2+-binding and Ca2+-modulated proteins, with pattern recognition receptors, e.g., Toll-like receptors (TLRs), the receptor for advanced glycation end products (RAGE), or scavenger rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______4577::b0186dd99a01227e52e82905d72ed88e
https://www.hzdr.de/publications/Publ-28872-2
https://www.hzdr.de/publications/Publ-28872-2