Zobrazeno 1 - 10
of 300
pro vyhledávání: '"Knaupp, AS"'
Autor:
Steffen Lippold, Karishma Mistry, Sunidhi Lenka, Kevin Whang, Peilu Liu, Sebastian Pitschi, Felix Kuhne, Dietmar Reusch, Lance Cadang, Alexander Knaupp, Saeed Izadi, Alexis Dunkle, Feng Yang, Tilman Schlothauer
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Human Fc gamma receptor IIa (FcγRIIa) or CD32a has two major allotypes with a single amino acid difference at position 131 (histidine or arginine). Differences in FcγRIIa allotypes are known to impact immunological responses such as the clinical ou
Externí odkaz:
https://doaj.org/article/69a3b2655a744a0981d1ba12450c4881
Autor:
Patricia Gerdes, Sue Mei Lim, Adam D. Ewing, Michael R. Larcombe, Dorothy Chan, Francisco J. Sanchez-Luque, Lucinda Walker, Alexander L. Carleton, Cini James, Anja S. Knaupp, Patricia E. Carreira, Christian M. Nefzger, Ryan Lister, Sandra R. Richardson, Jose M. Polo, Geoffrey J. Faulkner
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Retrotransposons are mobile genetic elements normally repressed by DNA methylation in differentiated cells. Here, the authors show that DNA hypomethylation in mouse induced pluripotent stem cells allows retrotransposons to jump, but this can be block
Externí odkaz:
https://doaj.org/article/b8c17138d7be4d378e40d7894f019bb7
Autor:
Bastiaan Laurens Duivelshof, Thomas Bouvarel, Sebastian Pirner, Vincent Larraillet, Alexander Knaupp, Hans Koll, Valentina D’Atri, Davy Guillarme
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16623 (2023)
Charge heterogeneity among therapeutic monoclonal antibodies (mAbs) is considered an important critical quality attribute and requires careful characterization to ensure safe and efficacious drug products. The charge heterogeneity among mAbs is the r
Externí odkaz:
https://doaj.org/article/058ad9f8adda431883f800c97660832e
Autor:
Christian M. Nefzger, Thierry Jardé, Akanksha Srivastava, Jan Schroeder, Fernando J. Rossello, Katja Horvay, Mirsada Prasko, Jacob M. Paynter, Joseph Chen, Chen-Fang Weng, Yu B. Y. Sun, Xiaodong Liu, Eva Chan, Nikita Deshpande, Xiaoli Chen, Y. Jinhua Li, Jahnvi Pflueger, Rebekah M. Engel, Anja S. Knaupp, Kirill Tsyganov, Susan K. Nilsson, Ryan Lister, Owen J. L. Rackham, Helen E. Abud, Jose M. Polo
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-8 (2022)
Abstract The impact of aging on intestinal stem cells (ISCs) has not been fully elucidated. In this study, we identified widespread epigenetic and transcriptional alterations in old ISCs. Using a reprogramming algorithm, we identified a set of key tr
Externí odkaz:
https://doaj.org/article/325c54d2ea294a94afa02fa43f4f567c
Autor:
Bouvarel, Thomas, Duivelshof, Bastiaan L., Camperi, Julien, Schlothauer, Tilman, Knaupp, Alexander, Stella, Cinzia, Guillarme, Davy
Publikováno v:
In Journal of Chromatography A 25 October 2022 1682
Autor:
Mohenska, Monika, Tan, Nathalia M., Tokolyi, Alex, Furtado, Milena B., Costa, Mauro W., Perry, Andrew J., Hatwell-Humble, Jessica, van Duijvenboden, Karel, Nim, Hieu T., Ji, Yuan M.M., Charitakis, Natalie, Bienroth, Denis, Bolk, Francesca, Vivien, Celine, Knaupp, Anja S., Powell, David R., Elliott, David A., Porrello, Enzo R., Nilsson, Susan K., del Monte-Nieto, Gonzalo, Rosenthal, Nadia A., Rossello, Fernando J., Polo, Jose M., Ramialison, Mirana
Publikováno v:
In Journal of Molecular and Cellular Cardiology February 2022 163:20-32
Publikováno v:
Advanced Genetics, Vol 3, Iss 4, Pp n/a-n/a (2022)
Abstract Transcription factors (TFs) are the master regulators of cellular identity, capable of driving cell fate transitions including differentiations, reprogramming, and transdifferentiations. Pioneer TFs recognize partial motifs exposed on nucleo
Externí odkaz:
https://doaj.org/article/840d753583ed4ad78a54e9a0279f9b78
Autor:
Christoph Gstöttner, Alexander Knaupp, Gestur Vidarsson, Dietmar Reusch, Tilman Schlothauer, Manfred Wuhrer, Elena Domínguez-Vega
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The impact of antibody glycoforms on FcγRIIa activation and immune responses is poorly understood. Yet, glycoform binding assessment remains one of the major analytical challenges requiring long enrichment or glycoengineering steps. Here, we develop
Externí odkaz:
https://doaj.org/article/9fdd4b98cb2049af8d3785c42cceb466
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