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t(r;14)(p14;q32) results in aberrant expression of FOXP1 in a case of diffuse large B-cell lymphoma

Autor: Fenton, JAL, Schuuring, E, Barrans, SL, Banham, AH, Rollinson, SJ, Morgan, GJ, Jack, AS, van Krieken, JHJM, Kluin, PM

Publikováno v: GENES CHROMOSOMES & CANCER, 45(2), 164-168. Wiley

Strong expression of Forkhead box-P1 (FOXP1), a winged-helix transcription factor, has been identified as an independent prognostic factor in diffuse large B-cell lymphoma (DLBCL). However, possible mechanisms of deregulation of this gene, on 3p14.1,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::2ec3618d1475ca7183eeea39eaeb9bef
https://research.rug.nl/en/publications/07ab6797-812f-40df-b12d-ca0b2e1a45c7

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Comparative genome analysis of cortactin and HSI: the significance of the F-actin binding repeat domain

Autor: van Rossum, AGSH, Schuuring-Scholtes, E, Seggelen, VV, Kluin, PM, Schuuring, E

Publikováno v: BMC Genomics, 6:15. BioMed Central Ltd.

Background: In human carcinomas, overexpression of cortactin correlates with poor prognosis. Cortactin is an F-actin-binding protein involved in cytoskeletal rearrangements and cell migration by promoting actin-related protein (Arp)2/3 mediated actin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::dd086dbd31abd9f6c4753fc6a23f901e
https://research.rug.nl/en/publications/a4f54277-5abe-4fa0-b699-e36d49a4b1a6

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Enteropathy-associated T-cell lymphoma presenting with eosinophilia

Autor: Hovenga, S, de Graaf, H, Joosten, P, van den Berg, GA, Storm, H, Langerak, AW, Kluin, PM, Kibbelaar, RE

Publikováno v: Netherlands Journal of Medicine, 61(1), 25-27. Van Zuiden Communications
Netherlands Journal of Medicine, 61(1), 25-27. van Zuiden Communications BV.

Hypereosinophilia can be related to various diseases; when it occurs without an obvious cause it is called idiopathic hypereosinophilic syndrome (IHES). We describe a patient with increasing eosinophilia, which in spite of extensive diagnostic proced

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::03ba946d2eb580fcd6960158a0b73591
https://pure.eur.nl/en/publications/cf344b33-9ca6-48fd-8af6-ae5a74446a7b

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Tyrosine phosphorylation in human lymphomas

Autor: Haralambieva, E, Jones, M., Roncador, GM, Cerroni, L, Lamant, L, Ott, G, Rosenwald, A, Sherman, C, Thorner, P, Kusec, R, Wood, KM, Campo, E, Falini, B, Ramsay, A, Marafioti, T, Stein, H, Kluin, PM, Pulford, K, Mason, DY

Publikováno v: Histochemical journal, 34(11-12), 545-552

In a previous study, we showed that the high level of protein tyrosine phosphorylation present in lymphomas containing an anaplastic lymphoma kinase (ALK) can be demonstrated in routinely processed paraffin tissue sections using immunolabelling techn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::1d753d82bda5b38770014a093ffd629c
https://research.rug.nl/en/publications/a611f24f-1f7e-4fb6-89e3-4f1bc0f96206

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Successful outcome with a 'quintuple approach' of posttransplant lymphoproliferative disorder

Autor: Schaar, CG, van der Pijl, JW, van Hoek, B, de Fijter, JW, Kluin, PM, van Krieken, JHJ, Terpstra, WE, Willemze, R, Kluin-Nelemans, HC

Publikováno v: Transplantation, 71(1), 47-52. LIPPINCOTT WILLIAMS & WILKINS

Background. The treatment of posttransplant lymphoproliferative disorder (PTLD) remains empirical. We review our treatment of seven cases of PTLD consisting of five interventions: 1) reduction of immunosuppression; 2) antiviral drugs; 3) interferon-a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::eda0cb8d7828bbe642173084e9eb0fd7
https://research.rug.nl/en/publications/e4df4554-b660-4d19-bff1-610e29eb5eea

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