Chimeric antigen receptor T cells engineered to recognize the P329G-mutated Fc part of effector-silenced tumor antigen-targeting human IgG1 antibodies enable modular targeting of solid tumors.

Autor: Stock S; Department of Medicine IV, Division of Clinical Pharmacology, University Hospital, Ludwig Maximilian University (LMU), Munich, Germany sophia.stock@med.uni-muenchen.de sebastian.kobold@med.uni-muenchen.de christian.klein.ck1@roche.com.; Department of Medicine III, University Hospital, Ludwig Maximilian University (LMU), Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany., Benmebarek MR; Department of Medicine IV, Division of Clinical Pharmacology, University Hospital, Ludwig Maximilian University (LMU), Munich, Germany.; National Cancer Institute (NCI), Bethesda, Maryland, USA., Kluever AK; Department of Medicine IV, Division of Clinical Pharmacology, University Hospital, Ludwig Maximilian University (LMU), Munich, Germany., Darowski D; Roche Innovation Center Zurich, Roche Pharma Research & Early Development, Schlieren, Switzerland.; Innovent Biologics (Suzhou) Co., Ltd, Suzhou, Jiangsu, China., Jost C; Roche Innovation Center Zurich, Roche Pharma Research & Early Development, Schlieren, Switzerland.; Athebio AG, Schlieren, Switzerland., Stubenrauch KG; Roche Innovation Center Munich, Penzberg, Germany., Benz J; Roche Innovation Center Basel, Basel, Switzerland., Freimoser-Grundschober A; Roche Innovation Center Zurich, Roche Pharma Research & Early Development, Schlieren, Switzerland., Moessner E; Roche Innovation Center Zurich, Roche Pharma Research & Early Development, Schlieren, Switzerland., Umana P; Roche Innovation Center Zurich, Roche Pharma Research & Early Development, Schlieren, Switzerland., Subklewe M; Department of Medicine III, University Hospital, Ludwig Maximilian University (LMU), Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany., Endres S; Department of Medicine IV, Division of Clinical Pharmacology, University Hospital, Ludwig Maximilian University (LMU), Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany.; Einheit für Klinische Pharmakologie (EKLiP), Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU), Neuherberg, Germany., Klein C; Roche Innovation Center Zurich, Roche Pharma Research & Early Development, Schlieren, Switzerland sophia.stock@med.uni-muenchen.de sebastian.kobold@med.uni-muenchen.de christian.klein.ck1@roche.com., Kobold S; Department of Medicine IV, Division of Clinical Pharmacology, University Hospital, Ludwig Maximilian University (LMU), Munich, Germany sophia.stock@med.uni-muenchen.de sebastian.kobold@med.uni-muenchen.de christian.klein.ck1@roche.com.; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany.; Einheit für Klinische Pharmakologie (EKLiP), Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU), Neuherberg, Germany.

Publikováno v: Journal for immunotherapy of cancer [J Immunother Cancer] 2022 Jul; Vol. 10 (7).

A Simple and Effective Flow Cytometry-Based Method for Identification and Quantification of Tissue Infiltrated Leukocyte Subpopulations in a Mouse Model of Peripheral Arterial Disease.

Autor: Kumaraswami K; Walter-Brendel-Centre of Experimental Medicine, University Hospital, LMU Munich, 81377 Munich, Germany.; Biomedical Center, Institute of Cardiovascular Physiology and Pathophysiology, LMU Munich, 82152 Planegg-Martinsried, Germany., Salei N; Walter-Brendel-Centre of Experimental Medicine, University Hospital, LMU Munich, 81377 Munich, Germany.; Biomedical Center, Institute of Cardiovascular Physiology and Pathophysiology, LMU Munich, 82152 Planegg-Martinsried, Germany., Beck S; Walter-Brendel-Centre of Experimental Medicine, University Hospital, LMU Munich, 81377 Munich, Germany.; Biomedical Center, Institute of Cardiovascular Physiology and Pathophysiology, LMU Munich, 82152 Planegg-Martinsried, Germany., Rambichler S; Walter-Brendel-Centre of Experimental Medicine, University Hospital, LMU Munich, 81377 Munich, Germany.; Biomedical Center, Institute of Cardiovascular Physiology and Pathophysiology, LMU Munich, 82152 Planegg-Martinsried, Germany., Kluever AK; Walter-Brendel-Centre of Experimental Medicine, University Hospital, LMU Munich, 81377 Munich, Germany.; Biomedical Center, Institute of Cardiovascular Physiology and Pathophysiology, LMU Munich, 82152 Planegg-Martinsried, Germany., Lasch M; Walter-Brendel-Centre of Experimental Medicine, University Hospital, LMU Munich, 81377 Munich, Germany.; Biomedical Center, Institute of Cardiovascular Physiology and Pathophysiology, LMU Munich, 82152 Planegg-Martinsried, Germany.; Department of Otorhinolaryngology, Head & Neck Surgery, University Hospital, LMU Munich, 81377 Munich, Germany., Richter L; Core Facility Flow Cytometry, Biomedical Centre, LMU Munich, 82152 Planegg-Martinsried, Germany., Schraml BU; Walter-Brendel-Centre of Experimental Medicine, University Hospital, LMU Munich, 81377 Munich, Germany.; Biomedical Center, Institute of Cardiovascular Physiology and Pathophysiology, LMU Munich, 82152 Planegg-Martinsried, Germany., Deindl E; Walter-Brendel-Centre of Experimental Medicine, University Hospital, LMU Munich, 81377 Munich, Germany.; Biomedical Center, Institute of Cardiovascular Physiology and Pathophysiology, LMU Munich, 82152 Planegg-Martinsried, Germany.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2020 May 19; Vol. 21 (10). Date of Electronic Publication: 2020 May 19.

Is there a Chance to Promote Arteriogenesis by DPP4 Inhibitors Even in Type 2 Diabetes? A Critical Review.

Autor: Vedantham S; MedGenome Labs Ltd., Bangalore, Karnataka 560099, India. srinivasan.vedantham@gmail.com.; School of Chemical Biotechnology, SASTRA University, Thanjavur 613401, India. srinivasan.vedantham@gmail.com., Kluever AK; Walter-Brendel-Centre of Experimental Medicine, University Hospital, LMU Munich, 80336 Munich, Germany. annakluever97@gmail.com., Deindl E; Walter-Brendel-Centre of Experimental Medicine, University Hospital, LMU Munich, 80336 Munich, Germany. elisabeth.deindl@med.uni-muenchen.de.

Publikováno v: Cells [Cells] 2018 Oct 22; Vol. 7 (10). Date of Electronic Publication: 2018 Oct 22.

Extracellular RNA, a Potential Drug Target for Alleviating Atherosclerosis, Ischemia/Reperfusion Injury and Organ Transplantation.

Autor: Kluever AK; Walter-Brendel-Centre of Experimental Medicine, University Hospital, LMU Munich, Munich, Germany., Deindl E; Walter-Brendel-Centre of Experimental Medicine, University Hospital, LMU Munich, Munich, Germany.

Publikováno v: Current pharmaceutical biotechnology [Curr Pharm Biotechnol] 2018; Vol. 19 (15), pp. 1189-1195.