MMP-9 gene variants increase the risk for non-atopic asthma in children

Autor: Vogelberg Christian, Illig Thomas, Klopp Norman, Depner Martin, Pinto Leonardo A, von Mutius Erika, Kabesch Michael

Publikováno v: Respiratory Research, Vol 11, Iss 1, p 23 (2010)

Abstract Background Atopic and non-atopic wheezing may be caused by different etiologies: while eosinophils are more important in atopic asthmatic wheezers, neutrophils are predominantly found in BAL samples of young children with wheezing. Both neut

Externí odkaz: https://doaj.org/article/df0369d6bf464f579d1fb8ca9f506ac6

Association between variations in the TLR4 gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL-cholesterol

Autor: Meisinger Christine, Thorand Barbara, Klopp Norman, Khuseyinova Natalie, Müller Martina, Baumert Jens, Kolz Melanie, Herder Christian, Koenig Wolfgang, Illig Thomas

Publikováno v: BMC Medical Genetics, Vol 9, Iss 1, p 9 (2008)

Abstract Background Toll-like receptor 4 (TLR4), the signaling receptor for lipopolysaccharides, is an important member of the innate immunity system. Since several studies have suggested that type 2 diabetes might be associated with changes in the i

Externí odkaz: https://doaj.org/article/671a1db483764d319d25128277ae49d6

The role of polymorphisms in ADAM33, a disintegrin and metalloprotease 33, in childhood asthma and lung function in two German populations

Autor: Klopp Norman, Illig Thomas, Lau Susanne, Niggemann Bodo, Vogelberg Christian, Weiland Stephan K, Schoen Carola, Depner Martin, Schedel Michaela, Wahn Ulrich, von Mutius Erika, Nickel Renate, Kabesch Michael

Publikováno v: Respiratory Research, Vol 7, Iss 1, p 91 (2006)

Abstract Background ADAM33, the first asthma candidate gene identified by positional cloning, may be associated with childhood asthma, lung function decline and bronchial hyperresponsiveness. However, replication results have been inconclusive in sma

Externí odkaz: https://doaj.org/article/0b9be436c5044e2d887071c36343e807

Disentangling the genetics of lean mass

Autor: Karasik, David, Zillikens, M Carola, Hsu, Yi-Hsiang, Aghdassi, Ali, Akesson, Kristina, Amin, Najaf, Barroso, Inês, Bennett, David A, Bertram, Lars, Bochud, Murielle, Borecki, Ingrid B, Broer, Linda, Buchman, Aron S, Byberg, Liisa, Campbell, Harry, Campos-Obando, Natalia, Cauley, Jane A, Cawthon, Peggy M, Chambers, John C, Chen, Zhao, Cho, Nam H, Choi, Hyung Jin, Chou, Wen-Chi, Cummings, Steven R, de Groot, Lisette C P G M, De Jager, Phillip L, Demuth, Ilja, Diatchenko, Luda, Econs, Michael J, Eiriksdottir, Gudny, Enneman, Anke W, Eriksson, Joel, Eriksson, Johan G, Estrada, Karol, Evans, Daniel S, Feitosa, Mary F, Fu, Mao, Gieger, Christian, Grallert, Harald, Gudnason, Vilmundur, Lenore, Launer J, Hayward, Caroline, Hofman, Albert, Homuth, Georg, Huffman, Kim M, Husted, Lise B, Illig, Thomas, Ingelsson, Erik, Ittermann, Till, Jansson, John-Olov, Johnson, Toby, Biffar, Reiner, Jordan, Joanne M, Jula, Antti, Karlsson, Magnus, Khaw, Kay-Tee, Kilpeläinen, Tuomas O, Klopp, Norman, Kloth, Jacqueline S L, Koller, Daniel L, Kooner, Jaspal S, Kraus, William E, Kritchevsky, Stephen, Kutalik, Zoltán, Kuulasmaa, Teemu, Kuusisto, Johanna, Laakso, Markku, Lahti, Jari, Lang, Thomas, Langdahl, Bente L, Lerch, Markus M, Lewis, Joshua R, Lill, Christina, Lind, Lars, Lindgren, Cecilia, Liu, Yongmei, Livshits, Gregory, Ljunggren, Östen, Loos, Ruth J F, Lorentzon, Mattias, Luan, Jian'an, Luben, Robert N, Malkin, Ida, McGuigan, Fiona E, Medina-Gomez, Carolina, Meitinger, Thomas, Melhus, Håkan, Mellström, Dan, Michaëlsson, Karl, Mitchell, Braxton D, Morris, Andrew P, Mosekilde, Leif, Nethander, Maria, Newman, Anne B, O'Connell, Jeffery R, Oostra, Ben A, Orwoll, Eric S, Palotie, Aarno, Peacock, Munro, Perola, Markus, Peters, Annette, Prince, Richard L, Psaty, Bruce M, Räikkönen, Katri, Ralston, Stuart H, Ripatti, Samuli, Rivadeneira, Fernando, Robbins, John A, Rotter, Jerome I, Rudan, Igor, Salomaa, Veikko, Satterfield, Suzanne, Schipf, Sabine, Shin, Chan Soo, Smith, Albert V, Smith, Shad B, Soranzo, Nicole, Spector, Timothy D, Stančáková, Alena, Stefansson, Kari, Steinhagen-Thiessen, Elisabeth, Stolk, Lisette, Streeten, Elizabeth A, Styrkarsdottir, Unnur, Swart, Karin M A, Thompson, Patricia, Thomson, Cynthia A, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Tikkanen, Emmi, Tranah, Gregory J, Uitterlinden, André G, van Duijn, Cornelia M, van Schoor, Natasja M, Vandenput, Liesbeth, Vollenweider, Peter, Völzke, Henry, Wactawski-Wende, Jean, Walker, Mark, J Wareham, Nicholas, Waterworth, Dawn, Weedon, Michael N, Wichmann, H-Erich, Widen, Elisabeth, Williams, Frances M K, Wilson, James F, Wright, Nicole C, Yerges-Armstrong, Laura M, Yu, Lei, Zhang, Weihua, Zhao, Jing Hua, Zhou, Yanhua, Nielson, Carrie M, Harris, Tamara B, Demissie, Serkalem, Kiel, Douglas P, Ohlsson, Claes

Publikováno v: In The American Journal of Clinical Nutrition February 2019 109(2):276-287

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