Mutation Status of KRAS, BRAF, PIK3CA and Expression Level of AREG and EREG Identify Responders to Cetuximab in a Large Panel of Patient Derived Colorectal Carcinoma Xenografts of All Four UICC Stages

Autor: Irina Klaman, René Mantke, Tobias Mayr, Klinikum Magdeburg, A. Rosenthal, Karsten Ridwelski, R. Pauli, K. Hellwig, C. Radke, Iduna Fichtner, K. Hertel, Michael Becker, Matthias Pross, K. Stecker, B. Hinzmann, K. Kretschmar, Jens Hoffmann, J Pertschy, Molekulare Medizin, Klinik für Allgemein-und Viszeralchirurgie

Publikováno v: Journal of Cancer Therapy. :678-693

To advance preclinical testing of novel targeted drugs in colorectal cancer (CRC) we established a panel of 133 mouse xenograft models from fresh tumor specimens of 239 patients with CRC of all four UICC stages. A subgroup of 67 xenograft models was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::916c304b42bbe7e9189c364084f4ff4c
https://doi.org/10.4236/jct.2013.42083

SPINE20 Recommendations 2024 -Spinal Disability: Social Inclusion as a Key to Prevention and Management.

Autor: Menezes CM; Department of Locomotor Apparatus, Federal University of Minas Gerais, Belo Horizonte, Brazil., Tucci C; Centro de Estudos e Promoção de Políticas em Saúde, Hospital Israelita Albert Einstein, São Paulo, Brazil., Tamai K; Department of Orthopedic Surgery, Osaka Metropolitan University, Osaka, Japan., Chhabra HS; Department of Spine and Rehabilitation, Sri Balaji Action Medical Institute, New Delhi, India., Alhelal FH; Department of Orthopedics, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia., Bussières AE; Department of Chiropractic, Université du Québec à Trois-Rivières, Trois-Rivieres, QC, Canada., Muehlbauer EJ; Executive Office, North American Spine Society, Chicago, USA., Roberts L; School of Health Sciences, University of Southampton, Southampton, UK., Alsobayel HI; Department of Rehabilitation Sciences, King Saud University, Riyadh, Saudi Arabia., Barneschi G; Department of Orthopedics, University of Florence, Florence, Italy., Campello MA; Department of Orthopedic Surgery, New York University Grossman School of Medicine, New York, NY, USA., Côté P; Institute for Disability and Rehabilitation Research and Faculty of Health Sciences, Ontario Tech University, Oshawa, ON, Canada., Duchén Rodríguez LM; Department of Neurosurgery and Spine Surgery, Center for Neurological Diseases, UPEA/UCEBOL, Santa Cruz, Bolivia., Cristante AF; Department of Orthopedic Surgery, University of São Paulo, São Paulo, Brazil., Kamra K; The Spinal Foundation, Delhi, India., Kitamura K; Department of Orthopaedic Surgery, National Defense Medical College, Saitama, Japan., Meves R; Department of Orthopedic, Santa Casa Spine Center, São Paulo, Brazil., Risso-Neto MI; Department of Orthopedic, Universidade Estadual de Campinas, São Paulo, Brazil., Vlok AJ; Division of Neurosurgery, Stellenbosch University, Cape Town, South Africa., Wadhwa S; Department of Physical Medicine and Rehabilitation, All India Institute of Medical Sciences, New Delhi, India., Wiechert K; Department of spine, Michel Spine Center, Hamburg, Germany., Yurac R; Department of Orthopedic, University del Desarrollo, Clinica Alemana, Santiago, Chile., Blattert T; Department of Orthopedic, Interdisciplinary Spine Center, Ingolstadt, Germany., Costanzo G; Department of Orthopedic Surgery, Università Sapienza Roma, Rome, Italy., Darwono B; Department of Orthopedic Surgery, Gading Pluit Hospital, Jakarta, Indonesia., Nordin M; Departments of Orthopaedics and Environmental Medicine, New York University, New York, NY, USA., Al Athbah YS; Department of Orthopedic services, Presidency of State Security, Riyadh, Saudi Arabia., Alturkistany A; Department of Orthopedic, King Faisal Specialist Hospital & Research Center, Jeddah, Saudi Arabia., Chahal R; Department of Spinal Surgery, Sir Ganga Ram Hospital, New Delhi, India., Franke J; Department of Orthopedics, Klinikum Magdeburg gGmbH, Magdeburg, Germany., Ito M; Department of Orthopedic Surgery, National Hospital Organization Hokkaido Medical Center, Sapporo, Japan., Arand M; Department Trauma-, Reconstructive- and Orthopaedic Surgery, General Hospital and Trauma Center Ludwigsburg, Ludwigsburg, Germany., Pereira P; Department of Neurosurgery, ULS São João, University of Porto, Porto, Portugal., Ruosi C; Public Health Department, Federico II University Napoli, Napoli, Italy., Sullivan WJ; Executive Office, North American Spine Society, Chicago, USA., Andújar ALF; Department of Pediatric Orthopedic Surgery, Hospital Infantil Joana de Gusmão, Florianópolis, Brazil., Ribeiro CH; Executive Office, Sociedade Brasileira de Coluna, Rio de Janeiro, Brazil., Carelli LE; Department of Traumatoloy and Orthopedics, National Institute of Traumatology and Orthopaedics, Rio de Janeiro, Brazil., Sardá J Jr; Departament of Psychology, Vale do Itajaí University - Univali, Itajaí, Brazil., Machado ALGE; Business School, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil., AlEissa S; Department of Orthopedics, King Abdulaziz Medical City, Riyadh, Saudi Arabia.

Publikováno v: Global spine journal [Global Spine J] 2024 Oct 10, pp. 21925682241290226. Date of Electronic Publication: 2024 Oct 10.

[Outpatient and "Admission-Substituting" Interventions in Vascular Surgery - What is Feasible and Where are the Limits? Previous and New Legal Requirements and their Implementation in Practice].

Autor: Barth U; Klinik für Allgemein-, Viszeral- und Gefäßchirurgie, Helios Klinik Jerichower Land Burg, Burg, Deutschland., Lehmann M; Klinik für Allgemein-, Viszeral- und Gefäßchirurgie, Helios Klinik Jerichower Land Burg, Burg, Deutschland., Tautenhahn J; Klinik für Gefäßchirurgie, Klinikum Magdeburg gGmbH, Magdeburg, Deutschland., Meyer F; Klinik für Allgemein-, Viszeral-, Gefäß- und Transplantationschirurgie, Universitätsklinikum Magdeburg A.ö.R., Magdeburg, Deutschland., Halloul Z; Arbeitsbereich Gefäßchirurgie, Klinik für Allgemein-, Viszeral-, Gefäß- und Transplantationschirurgie, Universitätsklinikum Magdeburg, Magdeburg, Deutschland.

Publikováno v: Zentralblatt fur Chirurgie [Zentralbl Chir] 2024 Oct; Vol. 149 (5), pp. 458-467. Date of Electronic Publication: 2023 Aug 10.

Radiofrequency Denervation of the Spine and the Sacroiliac Joint: A Systematic Review based on the Grades of Recommendations, Assesment, Development, and Evaluation Approach Resulting in a German National Guideline.

Autor: Klessinger S; Neurochirurgie Biberach, Biberach, Germany.; Universitätsklinikum Ulm, Ulm, Germany., Casser HR; DRK Schmerz-Zentrum, Mainz, Germany., Gillner S; Sana Krankenhaus Benrath, Düsseldorf, Germany., Koepp H; Wirbelsäulenzentrum, St Josefs-Hospital, Wiesbaden, Germany., Kopf A; Klinik für Anästhesiologie mit Schwerpunkt operative Intensivmedizin, Charité-Universitätsmedizin Berlin, Berlin, Germany., Legat M; Schmerzzentrum Zofingen, Zofingen, Switzerland., Meiler K; Städtisches Klinikum Magdeburg, Magdeburg, Germany., Norda H; UVSD SchmerzLOS eV, Neumünster, Germany., Schneider M; alphamed Bamberg, Bamberg, Germany., Scholz M; ATOS Orthopädische Klinik Braunfels GmbH & Co KG, Braunfels, Germany., Slotty PJ; Universitätsklinikum Düsseldorf, Düsseldorf, Germany., Tronnier V; Universitätsklinikum Schleswig-Holstein, Lübeck, Germany., Vazan M; Wirbelsäulen- und Rückenzentrum Dresden, Praxis für Neurochirurgie, Dresden, Germany., Wiechert K; Rückenzentrum am Michel, Hamburg, Germany.

Publikováno v: Global spine journal [Global Spine J] 2024 Sep; Vol. 14 (7), pp. 2124-2154. Date of Electronic Publication: 2024 Feb 06.

Relevance of different prognostic scores in primary CNS lymphoma in the era of intensified treatment regimens: A retrospective, multicenter analysis of 174 patients.

Autor: Zeremski V; Department of Hematology and Oncology, Medical Faculty, Otto von Guericke University Magdeburg, Magdeburg, Germany., Adolph L; Department of Internal Medicine III, Ludwig-Maximilians-University Hospital, Munich, Germany., Beer S; Department of Hematology and Oncology, University Hospital Tuebingen, Tuebingen, Germany., Berisha M; Department of Hematology and Oncology, Medical Faculty, Otto von Guericke University Magdeburg, Magdeburg, Germany.; Department of Internal Medicine 5, Hematology and Clinical Oncology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), University Hospital Erlangen, Erlangen, Germany., Jacobs B; Department of Internal Medicine 5, Hematology and Clinical Oncology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), University Hospital Erlangen, Erlangen, Germany., Kahl C; Department of Hematology, Oncology and Palliative Care, Klinikum Magdeburg, Magdeburg, Germany.; Department of Hematology, Oncology, and Palliative Care, University Medical Center, University of Rostock, Rostock, Germany., Koenecke C; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany., Kropf S; Department of Biometry and Medical Informatics, Medical Faculty, Otto von Guericke University Magdeburg, Magdeburg, Germany., Panse J; Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Medical Faculty, RWTH Aachen University, Aachen, Germany.; Center for Integrated Oncology (CIO), Aachen, Bonn, Cologne, Düsseldorf (ABCD), Aachen, Germany., Petersen J; Department of Hematology, Cell Therapy, Hemostaseology and Infectious Diseases, Leipzig University Medical Center, Leipzig, Germany., Schmidt-Hieber M; Clinic of Hematology, Oncology, Pneumology and Nephrology, Carl-Thiem-Hospital Cottbus, Cottbus, Germany., Schneider J; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany., Vucinic V; Department of Hematology, Cell Therapy, Hemostaseology and Infectious Diseases, Leipzig University Medical Center, Leipzig, Germany., Walter J; Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Medical Faculty, RWTH Aachen University, Aachen, Germany.; Center for Integrated Oncology (CIO), Aachen, Bonn, Cologne, Düsseldorf (ABCD), Aachen, Germany., Weigert O; Department of Internal Medicine III, Ludwig-Maximilians-University Hospital, Munich, Germany., Witte HM; Department of Hematology and Oncology, Federal Armed Hospital Ulm, Ulm, Germany., Mougiakakos D; Department of Hematology and Oncology, Medical Faculty, Otto von Guericke University Magdeburg, Magdeburg, Germany.; Department of Internal Medicine 5, Hematology and Clinical Oncology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), University Hospital Erlangen, Erlangen, Germany.

Publikováno v: European journal of haematology [Eur J Haematol] 2024 Apr; Vol. 112 (4), pp. 641-649. Date of Electronic Publication: 2024 Jan 02.