Zobrazeno 1 - 10
of 1 505
pro vyhledávání: '"Klinger, KW"'
Autor:
Deepak Rajpal, Stephen L. Madden, Joshi P, Klinger Kw, Pande Rs, Sardi Sp, Angel Cedazo-Minguez, Erin Teeple, Amilcar Flores-Morales, Dinesh Kumar, Latta Mahieu M, Huang Y
Understanding disease biology at a cellular level from disease specific tissues is imperative for effective drug development for complex neurodegenerative diseases. We profiled 87,086 nuclei from putamen tissue of healthy controls, Parkinson’s Dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07d078e36ab2d2e50d971fd081149c1f
https://doi.org/10.1101/2021.05.06.442950
https://doi.org/10.1101/2021.05.06.442950
Autor:
Klinger Kw, Joshi P, Amilcar Flores-Morales, Dinesh Kumar, Angel Cedazo-Minguez, Sardi P, Deepak Rajpal, Stephen L. Madden, Pande Rs, Erin Teeple, Huang Y, Karambe A, Latta-Mahieu M
The role of oligodendrocytes in neurodegenerative diseases remains incompletely understood and largely unexplored at the single cell level. We profiled 87,086 single nuclei from human brain putamen region for healthy control, Parkinson’s Disease (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf6249bf3d4f9795c445956ca1466f72
https://doi.org/10.1101/2021.05.06.442967
https://doi.org/10.1101/2021.05.06.442967
Autor:
Srinivas Shankara, Stephen L. Madden, Erin Teeple, Khushboo Jindal, S. Pablo Sardi, Beril Kiragasi, Can Kayatekin, Siddharth Annaldasula, Dinesh Kumar, Ann Byrne, Klinger Kw, Lilly Chai, Mahdiar Sadeghi
Alpha-synuclein (SNCA) aggregates are pathological hallmarks of synucleinopathies, neurodegenerative disorders including Parkinson’s Disease (PD) and Lewy Body Dementia (LBD). Functional networks are not yet well-characterized for SNCA by CNS cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41970ad3c85a1d7016b02ad3fe246330
https://doi.org/10.1101/2020.06.05.137166
https://doi.org/10.1101/2020.06.05.137166
Autor:
Hall, Bradley1 brad.hall@bio-techne.com, Milligan, John N.1, Kelnar, Kevin1, Hallmark, Elliot1, Ashton, Jacob D.1, Parker, Connor A.1, Filipovic-Sadic, Stela1, Sharp, Abigail2, Eagle, Samantha2, Rodgers, Nissa2, Leung, Marco2,3, Mathew, Mariam T.2,3, Grissom, Luke4, Post, Rebecca4, Teran, Natasa5, Latham, Gary J.1
Publikováno v:
Archives of Pathology & Laboratory Medicine. Oct2024, Vol. 148 Issue 10, p1135-1144. 10p.
Autor:
Husson H; Rare and Neurologic Diseases Research, Sanofi, Framingham, MA 01701, USA., Bukanov NO; Rare and Neurologic Diseases Research, Sanofi, Framingham, MA 01701, USA., Moreno S; Rare and Neurologic Diseases Research, Sanofi, Framingham, MA 01701, USA., Smith MM; Rare and Neurologic Diseases Research, Sanofi, Framingham, MA 01701, USA., Richards B; Translational Sciences, Sanofi, Framingham, MA 01701, USA., Zhu C; Translational Sciences, Sanofi, Framingham, MA 01701, USA., Picariello T; Rare and Neurologic Diseases Research, Sanofi, Framingham, MA 01701, USA., Park H; Pre-Development Sciences, Sanofi, Waltham, MA 02451, USA., Wang B; Pre-Development Sciences, Sanofi, Waltham, MA 02451, USA., Natoli TA; Rare and Neurologic Diseases Research, Sanofi, Framingham, MA 01701, USA., Smith LA; Rare and Neurologic Diseases Research, Sanofi, Framingham, MA 01701, USA., Zanotti S; Rare and Neurologic Diseases Research, Sanofi, Framingham, MA 01701, USA., Russo RJ; Rare and Neurologic Diseases Research, Sanofi, Framingham, MA 01701, USA., Madden SL; Translational Sciences, Sanofi, Framingham, MA 01701, USA., Klinger KW; Translational Sciences, Sanofi, Framingham, MA 01701, USA., Modur V; Rare Diseases Development, Sanofi, Cambridge, MA 02142, USA., Ibraghimov-Beskrovnaya O; Rare and Neurologic Diseases Research, Sanofi, Framingham, MA 01701, USA.
Publikováno v:
Human molecular genetics [Hum Mol Genet] 2020 Aug 29; Vol. 29 (15), pp. 2508-2522.
Autor:
Glascock J; Cure SMA, Elk Grove Village, IL, USA., Sampson J; Stanford University, Stanford, CA, USA., Connolly AM; Washington University School of Medicine, St. Louis, MO, USA., Darras BT; Department of Neurology, Boston Children's Hospital, Boston, MA, USA., Day JW; Stanford University, Stanford, CA, USA., Finkel R; Nemours Children's Hospital, University of Central Florida College of Medicine, Orlando, FL, USA., Howell RR; Miller School of Medicine, University of Miami, Miami, FL, USA., Klinger KW; Genzyme Corporation, a Sanofi Company, Framingham, MA, USA., Kuntz N; Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA., Prior T; Department of Molecular Pathology, Ohio State Wexner Medical Center, Columbus, OH, USA., Shieh PB; University of California Los Angeles, Los Angeles, CA, USA., Crawford TO; Departments of Neurology and Pediatrics, Johns Hopkins University, Baltimore, MD, USA., Kerr D; Generation Bio, Cambridge, MA, USA., Jarecki J; Cure SMA, Elk Grove Village, IL, USA.
Publikováno v:
Journal of neuromuscular diseases [J Neuromuscul Dis] 2020; Vol. 7 (2), pp. 97-100.
Autor:
Brady, Chloe A.1 (AUTHOR) chloe.brady@manchester.ac.uk, Ford, Laura B.2 (AUTHOR), Moss, Chloe1 (AUTHOR), Zou, Zhiyong1 (AUTHOR), Crocker, Ian P.1 (AUTHOR), Heazell, Alexander E. P.1,3 (AUTHOR)
Publikováno v:
Scientific Reports. 8/12/2024, Vol. 14 Issue 1, p1-14. 14p.
Autor:
Sajko, Mojca Čižek1, Prosenc, Bernarda1, Vidmar, Lovro1, Njenjić, Gordana2, Duff, Paula1, Peterlin, Borut1,3 borut.peterlin@kclj.si
Publikováno v:
Croatian Medical Journal. Jun2024, Vol. 65 Issue 3, p189-197. 9p.
Autor:
Schwartz, RH, Tsui, LC, Morgan, K, Klinger, KW, Richards, B, Anacleto, AI, Paradis, AJ, Markiewicz, D, Fujiwara, TM, Zielenski, J
The Hutterite population is a genetic isolate with an increased incidence of cystic fibrosis (CF). Previously we identified three CF haplotypes defined by polymorphisms flanking the CF transmembrane conductance regulator (CFTR) gene. ΔF508 was prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______961::a649b4e511d10b4c7c6f1690ea9ca432
http://hdl.handle.net/10722/42300
http://hdl.handle.net/10722/42300
Autor:
Zhang, Ran1,2 (AUTHOR), Liu, Yixiao2 (AUTHOR), Yu, Fengxi3 (AUTHOR), Xu, Guangxue4 (AUTHOR), Li, Lili5 (AUTHOR), Li, Baobin6 (AUTHOR), Lou, Zhiyong2 (AUTHOR) louzy@mail.tsinghua.edu.cn
Publikováno v:
PLoS Pathogens. 2/5/2024, Vol. 20 Issue 2, p1-20. 20p.