Ultrahigh electron mobility in suspended graphene

Autor: Bolotin, K. I., Sikes, K. J., Jiang, Z., Klima, M., Fudenberg, G., Hone, J., Kim, P., Stormer, H. L.

Publikováno v: Solid State Communications 146, 351-355 (2008)

We have achieved mobilities in excess of 200,000 cm^2/Vs at electron densities of ~2*10^11 cm^-2 by suspending single layer graphene. Suspension ~150 nm above a Si/SiO_2 gate electrode and electrical contacts to the graphene was achieved by a combina

Externí odkaz: http://arxiv.org/abs/0802.2389

Drug Discovery in Low Data Regimes: Leveraging a Computational Pipeline for the Discovery of Novel SARS-CoV-2 Nsp14-MTase Inhibitors.

Autor: Nigam A; Department of Computer Science, Stanford University.; Department of Genetics, Stanford University., Hurley MFD; Department of Chemistry, Temple University, Philadelphia, PA 19122, USA., Li F; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada., Konkoľová E; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic., Klíma M; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic., Trylčová J; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic., Pollice R; Chemical Physics Theory Group, Department of Chemistry, University of Toronto, 80 St. George St, Toronto, Ontario M5S 3H6, Canada.; Department of Computer Science, University of Toronto, 40 St. George St, Toronto, Ontario M5S 2E4, Canada.; Current affiliation: Stratingh Institute for Chemistry, University of Groningen, The Netherlands., Çinaroğlu SS; Structural Bioinformatics and Computational Biochemistry, Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK., Levin-Konigsberg R; Department of Genetics, Stanford University., Handjaya J; Chemical Physics Theory Group, Department of Chemistry, University of Toronto, 80 St. George St, Toronto, Ontario M5S 3H6, Canada.; Department of Computer Science, University of Toronto, 40 St. George St, Toronto, Ontario M5S 2E4, Canada., Schapira M; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario M5S 1A8, Canada., Chau I; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada., Perveen S; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada., Ng HL; Department of Biochemistry and Molecular Biophysics, Kansas State University, Manhattan, KS 66506, USA., Ümit Kaniskan H; Department of Pharmacological Sciences and Oncological Sciences, Mount Sinai Center for Therapeutics Discovery, Tisch Cancer Institute, Ichan School of Medicine at Mount Sinai, New York, NY, USA., Han Y; Department of Pharmacological Sciences and Oncological Sciences, Mount Sinai Center for Therapeutics Discovery, Tisch Cancer Institute, Ichan School of Medicine at Mount Sinai, New York, NY, USA., Singh S; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center., Gorgulla C; St. Jude Children's Research Hospital, Department of Structural Biology, Memphis, TN, USA.; Department of Physics, Faculty of Arts and Sciences, Harvard University, Cambridge, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, USA., Kundaje A; Department of Computer Science, Stanford University.; Department of Genetics, Stanford University., Jin J; Department of Pharmacological Sciences and Oncological Sciences, Mount Sinai Center for Therapeutics Discovery, Tisch Cancer Institute, Ichan School of Medicine at Mount Sinai, New York, NY, USA., Voelz VA; Department of Chemistry, Temple University, Philadelphia, PA 19122, USA., Weber J; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic., Nencka R; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic., Boura E; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic., Vedadi M; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.; QBI COVID-19 Research Group (QCRG), San Francisco, CA, USA.; Drug Discovery Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Aspuru-Guzik A; Chemical Physics Theory Group, Department of Chemistry, University of Toronto, 80 St. George St, Toronto, Ontario M5S 3H6, Canada.; Department of Computer Science, University of Toronto, 40 St. George St, Toronto, Ontario M5S 2E4, Canada.; Department of Chemical Engineering & Applied Chemistry, University of Toronto, Canada.; Department of Materials Science & Engineering, University of Toronto, Canada.; Vector Institute for Artificial Intelligence, Toronto, Canada.; Canadian Institute for Advanced Research (CIFAR), Toronto, ON, Canada.; Acceleration Consortium, University of Toronto, Toronto, ON, Canada.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jan 13. Date of Electronic Publication: 2024 Jan 13.

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Vinylphosphonate-based cyclic dinucleotides enhance STING-mediated cancer immunotherapy.

Autor: Dejmek M; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo náměstí 2, Prague 6, 166 10, Czech Republic., Brazdova A; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo náměstí 2, Prague 6, 166 10, Czech Republic; Department of Genetics and Microbiology, Faculty of Science, Charles University, Průmyslová 595, Vestec, 128 44, Prague, Czech Republic., Otava T; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo náměstí 2, Prague 6, 166 10, Czech Republic; Faculty of Food and Biochemical Technology, University of Chemistry and Technology, 166 28, Prague 6, Czech Republic., Polidarova MP; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo náměstí 2, Prague 6, 166 10, Czech Republic; Department of Genetics and Microbiology, Faculty of Science, Charles University, Průmyslová 595, Vestec, 128 44, Prague, Czech Republic., Klíma M; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo náměstí 2, Prague 6, 166 10, Czech Republic., Smola M; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo náměstí 2, Prague 6, 166 10, Czech Republic., Vavrina Z; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo náměstí 2, Prague 6, 166 10, Czech Republic; Faculty of Science, Charles University, Albertov 6, Prague 2, 128 00, Czech Republic., Buděšínský M; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo náměstí 2, Prague 6, 166 10, Czech Republic., Dračínský M; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo náměstí 2, Prague 6, 166 10, Czech Republic., Liboska R; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo náměstí 2, Prague 6, 166 10, Czech Republic., Boura E; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo náměstí 2, Prague 6, 166 10, Czech Republic., Birkuš G; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo náměstí 2, Prague 6, 166 10, Czech Republic. Electronic address: gabriel.birkus@uochb.cas.cz., Nencka R; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo náměstí 2, Prague 6, 166 10, Czech Republic. Electronic address: radim.nencka@uochb.cas.cz.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2023 Nov 05; Vol. 259, pp. 115685. Date of Electronic Publication: 2023 Jul 26.

Properties of water and argon clusters developed in supersonic expansions.

Autor: Klíma M; Department of Physical Chemistry, University of Chemistry and Technology in Prague, 166 28 Prague 6, Czech Republic., Celný D; Department of Physical Chemistry, University of Chemistry and Technology in Prague, 166 28 Prague 6, Czech Republic., Janek J; Department of Physical Chemistry, University of Chemistry and Technology in Prague, 166 28 Prague 6, Czech Republic., Kolafa J; Department of Physical Chemistry, University of Chemistry and Technology in Prague, 166 28 Prague 6, Czech Republic.

Publikováno v: The Journal of chemical physics [J Chem Phys] 2023 Sep 28; Vol. 159 (12).