Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kleyton Santos Veras"'
Autor:
Vanessa Pittol, Kleyton Santos Veras, Samuel Kaiser, Letícia Jacobi Danielli, Alexandre Meneghello Fuentefria, George González Ortega
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 58 (2022)
Abstract Poorly water-soluble drugs, such as the antifungal drug griseofulvin (GF), exhibit limited bioavailability, despite their high membrane permeability. Several technological approaches have been proposed to enhance the water solubility and bio
Externí odkaz:
https://doaj.org/article/0d49f09edb2c4d01ad2b105e925dade3
Autor:
Kleyton Santos Veras, Flávia Nathiely Silveira Fachel, Vanessa Pittol, Keth Ribeiro Garcia, Valquíria Linck Bassani, Venina dos Santos, Amélia Teresinha Henriques, Helder Ferreira Teixeira, Letícia Scherer Koester
Publikováno v:
Saudi Pharmaceutical Journal, Vol 27, Iss 8, Pp 1138-1145 (2019)
Rosmarinic acid (RA) is a phenolic compound that presents well-documented anti-inflammatory, antioxidant and antitumor activities, and based on its pharmacological potential and poor bioavailability, several solid dosage forms have been developed to
Externí odkaz:
https://doaj.org/article/1b75c53e56ae499bafba73b545d46d9c
Autor:
Kleyton Santos Veras, Flávia Nathiely Silveira Fachel, Bibiana Verlindo de Araújo, Helder Ferreira Teixeira, Letícia Scherer Koester
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2663 (2022)
Hydroxycinnamic acids (HCAs) such as caffeic acid (CA), chlorogenic acid (CGA), coumaric acid (COA) isomers, ferulic acid (FA) and rosmarinic acid (RA) are natural phenolic acids with widespread distribution in vegetal foods and well-documented pharm
Externí odkaz:
https://doaj.org/article/e7636e3c08774de8ba2b960fee2b1d2e
Autor:
Kleyton Santos Veras, Flávia Nathiely Silveira Fachel, Valquiria Linck Bassani, Helder Ferreira Teixeira, Letícia Scherer Koester
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2530 (2022)
Hydroxycinnamic acids (HCAs) are a subclass of phenolic acids presenting caffeic acid (CA), chlorogenic acid (CGA), coumaric acid (COA) isomers, ferulic acid (FA), and rosmarinic acid (RA) as the major representants, being broadly distributed into ve
Externí odkaz:
https://doaj.org/article/2e9a4694bb9741b9a6d7aea37fe17d44
Autor:
Vanessa Pittol, Kleyton Santos Veras, Eduarda Doneda, Ariane Dorneles Silva, Maria Gabriele Delagustin, Letícia Scherer Koester, Valquíria Linck Bassani
Publikováno v:
Pharmaceutical Development and Technology. 27:625-634
The complexation of herbal constituents with cyclodextrin has been a useful tool to improve their aqueous solubility. However, the simultaneous complexation of these compounds still lacks detailed studies. The present study investigated the multicomp
Autor:
Letícia Scherer Koester, Kleyton Santos Veras, Helder Ferreira Teixeira, Flávia Nathiely Silveira Fachel, Thiago Barcellos, Valquiria Linck Bassani, Amélia T. Henriques, Maria Gabriele Delagustin
Publikováno v:
Journal of Molecular Structure. 1195:582-590
Rosmarinic acid (RA) is a phenolic compound with remarkable antioxidant activity; however it presents low bioavailability. Cyclodextrin (CD) derivatives, such as hydroxypropyl-β-CD (HPβCD) and methyl-β-CD (MβCD), have been used to solve the low b
Autor:
Helder Ferreira Teixeira, Morgana Dal Prá, Roselena Silvestri Schuh, Valquiria Linck Bassani, Elizandra Braganhol, Amélia T. Henriques, Letícia Scherer Koester, Flávia Nathiely Silveira Fachel, Bruna Medeiros-Neves, Kleyton Santos Veras
Publikováno v:
Carbohydrate Polymers. 199:572-582
Mucoadhesive chitosan-coated nanoemulsions for rosmarinic acid (RA) nasal delivery were optimized. The optimum ratio between the formulation components that led to minimum droplet size and PDI, and maximal ζ-potential and RA content was obtained usi
Autor:
Vanessa Pittol, Kleyton Santos Veras, Venina dos Santos, Keth Ribeiro Garcia, Helder Ferreira Teixeira, Amélia T. Henriques, Flávia Nathiely Silveira Fachel, Valquiria Linck Bassani, Letícia Scherer Koester
Publikováno v:
Repositório Institucional da UFRGS
Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal, Vol 27, Iss 8, Pp 1138-1145 (2019)
Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal, Vol 27, Iss 8, Pp 1138-1145 (2019)
Rosmarinic acid (RA) is a phenolic compound that presents well-documented anti-inflammatory, antioxidant and antitumor activities, and based on its pharmacological potential and poor bioavailability, several solid dosage forms have been developed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c151217e5eaae467ef8b57e985a61bb
Autor:
Roselena Silvestri Schuh, Kleyton Santos Veras, Valquiria Linck Bassani, Elizandra Braganhol, Helder Ferreira Teixeira, Amélia T. Henriques, Flávia Nathiely Silveira Fachel, Letícia Scherer Koester
Publikováno v:
Neurochemistry international. 122
Neurodegenerative disorders (ND) are characterized by slow and progressive neuronal dysfunction induced by the degeneration of neuronal cells in the central nervous system (CNS). Recently, the neuroprotective effects of natural compounds with anti-in
Autor:
Bruna Medeiros-Neves, Kleyton Santos Veras, Marina Cardoso Nemitz, Valquiria Linck Bassani, Amélia T. Henriques, Letícia Scherer Koester, Helder Ferreira Teixeira, Flávia Nathiely Silveira Fachel
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 1083
Currently, there is an increasing interest on the development of topical formulations containing rosmarinic acid (RA) due to its well-documented antioxidant activity. This study aimed to develop and validate a stability-indicating ultra-fast liquid c