Gene panel diagnostics reveals new pathogenic variants in pulmonary arterial hypertension.

Autor: Eichstaedt CA; Center for Pulmonary Hypertension, Thoraxklinik Heidelberg gGmbH at Heidelberg University Hospital, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Röntgenstraße 1, 69126, Heidelberg, Germany. christina.eichstaedt@med.uni-heidelberg.de.; Laboratory for Molecular Genetic Diagnostics, Institute of Human Genetics, Heidelberg University, Röntgenstraße 1, 69126, Heidelberg, Germany. christina.eichstaedt@med.uni-heidelberg.de., Saßmannshausen Z; Laboratory for Molecular Genetic Diagnostics, Institute of Human Genetics, Heidelberg University, Röntgenstraße 1, 69126, Heidelberg, Germany., Shaukat M; Center for Pulmonary Hypertension, Thoraxklinik Heidelberg gGmbH at Heidelberg University Hospital, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Röntgenstraße 1, 69126, Heidelberg, Germany., Cao D; Center for Pulmonary Hypertension, Thoraxklinik Heidelberg gGmbH at Heidelberg University Hospital, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Röntgenstraße 1, 69126, Heidelberg, Germany., Xanthouli P; Center for Pulmonary Hypertension, Thoraxklinik Heidelberg gGmbH at Heidelberg University Hospital, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Röntgenstraße 1, 69126, Heidelberg, Germany., Gall H; Department of Pneumology, Medical and Policlinic II, University Hospital of Gießen and Marburg, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Gießen, Germany., Sommer N; Department of Pneumology, Medical and Policlinic II, University Hospital of Gießen and Marburg, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Gießen, Germany., Ghofrani HA; Department of Pneumology, Medical and Policlinic II, University Hospital of Gießen and Marburg, Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL), Gießen, Germany.; Department of Medicine, Imperial College, London, UK.; Department of Pneumology, Kerckhoff-Klinik, Bad Nauheim, Germany., Seyfarth HJ; Department of Pneumology, Medical Clinic II, University Hospital of Leipzig, Leipzig, Germany., Lerche M; Department of Pneumology, Medical Clinic II, University Hospital of Leipzig, Leipzig, Germany., Halank M; Medical Clinic I, University Hospital of Dresden, Dresden, Germany., Kleymann J; Medical Clinic I, University Hospital of Dresden, Dresden, Germany., Benjamin N; Center for Pulmonary Hypertension, Thoraxklinik Heidelberg gGmbH at Heidelberg University Hospital, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Röntgenstraße 1, 69126, Heidelberg, Germany., Harutyunova S; Center for Pulmonary Hypertension, Thoraxklinik Heidelberg gGmbH at Heidelberg University Hospital, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Röntgenstraße 1, 69126, Heidelberg, Germany., Egenlauf B; Center for Pulmonary Hypertension, Thoraxklinik Heidelberg gGmbH at Heidelberg University Hospital, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Röntgenstraße 1, 69126, Heidelberg, Germany., Milger K; Department of Internal Medicine V, Ludwig-Maximilian University of Munich; Asklepios Clinic Gauting, Comprehensive Pneumology Centre Munich (CPC), German Center for Lung Research (DZL), Munich, Germany., Rosenkranz S; Department III of Internal Medicine and Cologne Cardiovascular Research Center (CCRC), Cologne University Heart Center, Cologne, Germany., Ewert R; Department of Internal Medicine B-Cardiology, Intensive Care, Pulmonary Medicine and Infectious Diseases, University of Greifswald, Greifswald, Germany., Klose H; Department of Pneumology, Department of Medicine II, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Hoeper MM; Clinic for Pneumology, Hannover Medical School, Hannover and German Centre for Lung Research (DZL), Hannover, Germany., Olsson KM; Clinic for Pneumology, Hannover Medical School, Hannover and German Centre for Lung Research (DZL), Hannover, Germany., Lankeit M; Department of Internal Medicine and Cardiology, Campus Virchow Klinikum (CVK), Charité - University Medicine Berlin, Berlin, Germany.; Center for Thrombosis and Hemostasis, University Medical Center Mainz, Mainz, Germany., Lange TJ; Department of Internal Medicine II, Division of Pneumology, University Medical Center Regensburg, Regensburg, Germany., Hinderhofer K; Laboratory for Molecular Genetic Diagnostics, Institute of Human Genetics, Heidelberg University, Röntgenstraße 1, 69126, Heidelberg, Germany., Grünig E; Center for Pulmonary Hypertension, Thoraxklinik Heidelberg gGmbH at Heidelberg University Hospital, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Röntgenstraße 1, 69126, Heidelberg, Germany.

Publikováno v: Respiratory research [Respir Res] 2022 Mar 27; Vol. 23 (1), pp. 74. Date of Electronic Publication: 2022 Mar 27.

Septische Granulomatose als seltene Differenzialdiagnose rezidivierender pulmonaler Infektionen bei Erwachsenen. (German)

Autor: Kleymann, J., Schütz, C., Körholz, J., Taube, F., Vogler, M., Halank, M., Kolditz, M., Langner, S., Geberzahn, L., Holotiuk, O., Roesler, J., Koschel, D.

Publikováno v: Pneumologie; 2020, Vol. 74 Issue 10, p678-683, 6p

One Gene, Many Facets: Multiple Immune Pathway Dysregulation in SOCS1 Haploinsufficiency.

Autor: Körholz J; Department of Pediatrics, University Hospital and Medical Faculty Carl-Gustav-Carus, Technische Universität Dresden, Dresden, Germany.; UniversitätsCentrum für seltene Erkrankungen, Medizinische Fakultät Carl-Gustav-Carus, Technische Universität Dresden, Dresden, Germany., Gabrielyan A; Department of Pediatrics, University Hospital and Medical Faculty Carl-Gustav-Carus, Technische Universität Dresden, Dresden, Germany., Sowerby JM; Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, United Kingdom.; Department of Medicine, University of Cambridge, Cambridge, United Kingdom., Boschann F; Institute of Medical Genetics and Human Genetics, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany., Chen LS; Institute of Medical Microbiology and Virology, Medical Faculty Carl-Gustav-Carus, Technische Universität Dresden, Dresden, Germany., Paul D; Department of Pediatrics, University Hospital and Medical Faculty Carl-Gustav-Carus, Technische Universität Dresden, Dresden, Germany., Brandt D; Department of Pediatrics, University Hospital and Medical Faculty Carl-Gustav-Carus, Technische Universität Dresden, Dresden, Germany., Kleymann J; Department of Internal Medicine, Pneumology, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Kolditz M; Department of Internal Medicine, Pneumology, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Toepfner N; Department of Pediatrics, University Hospital and Medical Faculty Carl-Gustav-Carus, Technische Universität Dresden, Dresden, Germany., Knöfler R; Department of Pediatrics, University Hospital and Medical Faculty Carl-Gustav-Carus, Technische Universität Dresden, Dresden, Germany., Jacobsen EM; Department of Pediatrics, University Medical Center Ulm, Ulm, Germany., Wolf C; Department of Pediatrics, University Hospital and Medical Faculty Carl-Gustav-Carus, Technische Universität Dresden, Dresden, Germany., Conrad K; Institute of Immunology, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Röber N; Institute of Immunology, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Lee-Kirsch MA; Department of Pediatrics, University Hospital and Medical Faculty Carl-Gustav-Carus, Technische Universität Dresden, Dresden, Germany.; UniversitätsCentrum für seltene Erkrankungen, Medizinische Fakultät Carl-Gustav-Carus, Technische Universität Dresden, Dresden, Germany., Smith KGC; Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, United Kingdom.; Department of Medicine, University of Cambridge, Cambridge, United Kingdom., Mundlos S; Department of Medicine, University of Cambridge, Cambridge, United Kingdom.; Institute of Medical Genetics and Human Genetics, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.; Max Planck Institute for Molecular Genetics, Research Group (RG) Development and Disease, Berlin, Germany.; Berlin-Brandenburg Center for Regenerative Therapies, Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany., Berner R; Department of Pediatrics, University Hospital and Medical Faculty Carl-Gustav-Carus, Technische Universität Dresden, Dresden, Germany.; UniversitätsCentrum für seltene Erkrankungen, Medizinische Fakultät Carl-Gustav-Carus, Technische Universität Dresden, Dresden, Germany., Dalpke AH; Institute of Medical Microbiology and Virology, Medical Faculty Carl-Gustav-Carus, Technische Universität Dresden, Dresden, Germany., Schuetz C; Department of Pediatrics, University Hospital and Medical Faculty Carl-Gustav-Carus, Technische Universität Dresden, Dresden, Germany.; UniversitätsCentrum für seltene Erkrankungen, Medizinische Fakultät Carl-Gustav-Carus, Technische Universität Dresden, Dresden, Germany., Rae W; Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, United Kingdom.; Department of Medicine, University of Cambridge, Cambridge, United Kingdom.

Publikováno v: Frontiers in immunology [Front Immunol] 2021 Aug 05; Vol. 12, pp. 680334. Date of Electronic Publication: 2021 Aug 05 (Print Publication: 2021).

[Complications after Indwelling Pleural Catheter Implant for Symptomatic Recurrent Benign and Malignant Pleural Effusions].

Autor: Langner S; Bereich Pneumologie, Medizinische Klinik I, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden, Dresden., Koschel D; Bereich Pneumologie, Medizinische Klinik I, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden, Dresden.; Fachkrankenhaus Coswig, Abteilung Innere Medizin und Pneumologie, Lungenzentrum, Coswig., Kleymann J; Bereich Pneumologie, Medizinische Klinik I, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden, Dresden., Tausche K; Bereich Pneumologie, Medizinische Klinik I, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden, Dresden., Karl S; Bereich Pneumologie, Medizinische Klinik I, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden, Dresden., Frenzen F; Bereich Pneumologie, Medizinische Klinik I, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden, Dresden., Heberling M; Bereich Pneumologie, Medizinische Klinik I, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden, Dresden., Schulte-Hubbert B; Bereich Pneumologie, Medizinische Klinik I, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden, Dresden., Halank M; Bereich Pneumologie, Medizinische Klinik I, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden, Dresden., Kolditz M; Bereich Pneumologie, Medizinische Klinik I, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden, Dresden.

Publikováno v: Pneumologie (Stuttgart, Germany) [Pneumologie] 2020 Dec; Vol. 74 (12), pp. 864-870. Date of Electronic Publication: 2020 Jul 14.

[Large Pneumothorax in a Sleep Apnea Patient with CPAP without Previously Known Lung and Thoracic Diseases - a Case Report].

Autor: Langner S; Bereich Pneumologie, Medizinische Klinik I, Universitätsklinikum 'Carl Gustav Carus', Technische Universität Dresden., Kolditz M; Bereich Pneumologie, Medizinische Klinik I, Universitätsklinikum 'Carl Gustav Carus', Technische Universität Dresden., Kleymann J; Bereich Pneumologie, Medizinische Klinik I, Universitätsklinikum 'Carl Gustav Carus', Technische Universität Dresden., Tausche K; Bereich Pneumologie, Medizinische Klinik I, Universitätsklinikum 'Carl Gustav Carus', Technische Universität Dresden., Almeida AB; Bereich Thoraxchirurgie, Klinik für Viszeral-Thorax-Gefäßchirurgie, Universitätsklinikum 'Carl Gustav Carus', Technische Universität Dresden., Schweigert M; Bereich Thoraxchirurgie, Klinik für Viszeral-Thorax-Gefäßchirurgie, Universitätsklinikum 'Carl Gustav Carus', Technische Universität Dresden., Koschel D; Bereich Pneumologie, Medizinische Klinik I, Universitätsklinikum 'Carl Gustav Carus', Technische Universität Dresden.; Fachkrankenhaus Coswig, Zentrum für Pneumologie, Allergologie, Beatmungsmedizin und Thoraxchirurgie, Coswig.

Publikováno v: Pneumologie (Stuttgart, Germany) [Pneumologie] 2020 Apr; Vol. 74 (4), pp. 217-221. Date of Electronic Publication: 2020 Apr 09.