Why are different estimates of the effective reproductive number so different? A case study on COVID-19 in Germany.

Autor: Brockhaus EK; Chair of Statistical Methods and Econometrics, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany., Wolffram D; Chair of Statistical Methods and Econometrics, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.; Computational Statistics Group, Heidelberg Institute for Theoretical Studies (HITS), Heidelberg, Germany., Stadler T; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Osthege M; Institute of Bio- and Geosciences, IBG-1: Biotechnology, Forschungszentrum Jülich GmbH, Jülich, Germany.; Institute of Biotechnology, RWTH Aachen University, Aachen, Germany., Mitra T; Department of Systems Immunology and Braunschweig Integrated Centre of Systems Biology (BRICS), Helmholtz Centre for Infection Research, Braunschweig, Germany.; Current address: Kennedy Institute of Rheumatology, Nuffield Department of Orthopedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom., Littek JM; Chair of Statistical Methods and Econometrics, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany., Krymova E; Swiss Data Science Center, EPF Lausanne and ETH Zurich, Zurich, Switzerland., Klesen AJ; Chair of Statistical Methods and Econometrics, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany., Huisman JS; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.; Physics of Living Systems, Department of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America., Heyder S; Institute of Mathematics, Technische Universität Ilmenau, Ilmenau, Germany., Helleckes LM; Institute of Bio- and Geosciences, IBG-1: Biotechnology, Forschungszentrum Jülich GmbH, Jülich, Germany.; Institute of Biotechnology, RWTH Aachen University, Aachen, Germany., An der Heiden M; Robert Koch Institute, Berlin, Germany., Funk S; Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, United Kingdom.; Centre for Mathematical Modelling of Infectious Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom., Abbott S; Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, United Kingdom.; Centre for Mathematical Modelling of Infectious Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom., Bracher J; Chair of Statistical Methods and Econometrics, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.; Computational Statistics Group, Heidelberg Institute for Theoretical Studies (HITS), Heidelberg, Germany.

Publikováno v: PLoS computational biology [PLoS Comput Biol] 2023 Nov 27; Vol. 19 (11), pp. e1011653. Date of Electronic Publication: 2023 Nov 27 (Print Publication: 2023).