Nuclear Factor-κB Mediates TNF-α Inhibitory Effect on α2(I) Collagen (COL1A2) Gene Transcription in Human Dermal Fibroblasts

Autor: Kouba, D. J., Chung, K. -Y, Nishiyama, T., Vindevoghel, L., Kon, A., Klement, J. F., Uitto, J., Alain Mauviel

Publikováno v: Scopus-Elsevier

Among its plethora of activities as an inflammatory mediator, TNF-α has potent regulatory control on extracellular matrix production and degradation. Earlier studies have documented that TNF-α inhibits type I collagen gene (COL1A2) expression at th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69f9e8c1f963d229d69b770b38905bf2
https://doi.org/10.4049/jimmunol.162.7.4226

Species-specific lens activation of the thymidine kinase promoter by a single copy of the mouse alpha A-CRYBP1 site and loss of tissue specificity by multimerization

Autor: Sax, C M, Klement, J F, Piatigorsky, J

Publikováno v: Molecular and Cellular Biology; December 1990, Vol. 10 Issue: 12 p6813-6816, 4p

Relationship between promoter structure and template specificities exhibited by the bacteriophage T3 and T7 RNA polymerases.

Autor: Bailey, J N, Klement, J F, McAllister, W T

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America; May 1983, Vol. 80 Issue: 10 p2814-2818, 5p

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Nuclear factor-kappa B mediates TNF-alpha inhibitory effect on alpha 2(I) collagen (COL1A2) gene transcription in human dermal fibroblasts.

Autor: Kouba DJ; Department of Dermatology and Cutaneous Biology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA., Chung KY, Nishiyama T, Vindevoghel L, Kon A, Klement JF, Uitto J, Mauviel A

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 1999 Apr 01; Vol. 162 (7), pp. 4226-34.