Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Klemens, Horst"'
Autor:
Yang Li, Klemens Horst, Johannes Greven, Ümit Mert, Ludmila Lupu, Annette Palmer, Lena Doerfer, Qun Zhao, Xing Zhang, Rebecca Halbgebauer, Anita Ignatius, Ingo Marzi, Martijn van Griensven, Elizabeth Balmayor, Frank Hildebrand, Tom Eirik Mollnes, Markus Huber-Lang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundPolytrauma and hemorrhagic shock can lead to direct and indirect liver damage involving intricate pathophysiologic mechanisms. While hepatic function has been frequently highlighted, there is minimal research on how the receptor activator o
Externí odkaz:
https://doaj.org/article/0dd4a07f570e42239e70c8a2eeb84d2e
Autor:
Nan Zhou, Rald V. M. Groven, Klemens Horst, Ümit Mert, Johannes Greven, Tom Eirik Mollnes, Markus Huber-Lang, Martijn van Griensven, Frank Hildebrand, Elizabeth R. Balmayor
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundRespiratory failure can be a severe complication after polytrauma. Extensive systemic inflammation due to surgical interventions, as well as exacerbated post-traumatic immune responses influence the occurrence and progression of respiratory
Externí odkaz:
https://doaj.org/article/7684696c74d540418c2efae014825520
Autor:
Weining Yan, Felix Bläsius, Tabea Wahl, Frank Hildebrand, Elizabeth Rosado Balmayor, Johannes Greven, Klemens Horst
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0308228 (2024)
BackgroundChest injury is an important factor regarding the prognosis of patients with polytrauma (PT), and the rapid diagnosis of chest injury is of utmost importance. Therefore, the current study focused on patients' physiology and laboratory findi
Externí odkaz:
https://doaj.org/article/c3919015a37447278fd6051621be1f1f
Autor:
Bingduo Wang, Aliona Wöhler, Johannes Greven, Rebekka J. S. Salzmann, Cindy M. Keller, Tobias Tertel, Qun Zhao, Ümit Mert, Klemens Horst, Ludmila Lupu, Markus Huber-Lang, Martijn van Griensven, Tom Erik Mollnes, Sebastian Schaaf, Robert Schwab, Christian P. Strassburg, Ingo G. H. Schmidt-Wolf, Bernd Giebel, Frank Hildebrand, Veronika Lukacs-Kornek, Arnulf G. Willms, Miroslaw T. Kornek
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundDespite major advances in medicine, blood-borne biomarkers are urgently needed to support decision-making, including polytrauma. Here, we assessed serum-derived extracellular vesicles (EVs) as potential markers of decision-making in polytra
Externí odkaz:
https://doaj.org/article/3b8ca466e5ec44dabab96e095d62f58f
Autor:
Rald Victor Maria Groven, Johannes Greven, Ümit Mert, Klemens Horst, Qun Zhao, Taco Johan Blokhuis, Markus Huber-Lang, Frank Hildebrand, Martijn van Griensven
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionTwo trauma treatment principles are Early Total Care (ETC), and Damage Control Orthopedics (DCO). Cellular mechanisms that underlie the connection between treatment type, its systemic effects, and tissue regeneration are not fully known.
Externí odkaz:
https://doaj.org/article/670456bd62f44b06b06b868ff284ae21
Autor:
Felix M. Bläsius, Sebastian Wutzler, Philipp Störmann, Thomas Lustenberger, Michael Frink, Marc Maegele, Matthias Weuster, Jörg Bayer, Klemens Horst, Michael Caspers, Andreas Seekamp, Ingo Marzi, Frank Hildebrand, Hagen Andruszkow
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Multiple trauma patients with severe chest trauma are at increased risk for tracheostomy. While the risk factors associated with the need for tracheostomy are well established in the general critical care population, they have not yet been v
Externí odkaz:
https://doaj.org/article/b124480c755449fbaec184eb3b536870
Autor:
Felix Marius Bläsius, Johannes Greven, Weijun Guo, Eftychios Bolierakis, Zhizhen He, Cavan Lübke, Tim-Philipp Simon, Frank Hildebrand, Klemens Horst
Publikováno v:
European Journal of Medical Research, Vol 28, Iss 1, Pp 1-10 (2023)
Abstract Little is known about the impact of multiple trauma (MT)-related systemic hypoxia on osseous protein concentration of the hypoxia transcriptome. To shed light on this issue, we investigated erythropoietin (Epo), erythropoietin receptor (EpoR
Externí odkaz:
https://doaj.org/article/9a6925dde0a0475495cf59f2fc09ddf5
Autor:
Qun Zhao, Xing Zhang, You Li, Zhizhen He, Kang Qin, Eva Miriam Buhl, Ümit Mert, Klemens Horst, Frank Hildebrand, Elizabeth R. Balmayor, Johannes Greven
Publikováno v:
Pharmaceutics, Vol 16, Iss 2, p 279 (2024)
Objective: Existing research suggests that bone marrow-derived mesenchymal stem cells (BMSCs) may promote endogenous bone repair. This may be through the secretion of factors that stimulate repair processes or directly through differentiation into os
Externí odkaz:
https://doaj.org/article/70ea599175a7497cbf6f3a106a566a73
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/b8bedb95d06f49fe80931b2504d84d53
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/bf78ab1d1cde42b1afa6b2daa90c2bc9