Výsledky vyhledávání - "Klemencja Berghauzen"

Akademický článek

Alterations of BDNF and trkB mRNA expression in the 6-hydroxydopamine-induced model of preclinical stages of Parkinson's disease: an influence of chronic pramipexole in rats.

Autor: Klemencja Berghauzen-Maciejewska, Jadwiga Wardas, Barbara Kosmowska, Urszula Głowacka, Katarzyna Kuter, Krystyna Ossowska

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0117698 (2015)

Our recent study has indicated that a moderate lesion of the mesostriatal and mesolimbic pathways in rats, modelling preclinical stages of Parkinson's disease, induces a depressive-like behaviour which is reversed by chronic treatment with pramipexol

Externí odkaz: https://doaj.org/article/c90d04b5ea71432d81eb2622b841e6ba

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Inhibition of Excessive Glutamatergic Transmission in the Ventral Thalamic Nuclei by a Selective Adenosine A1 Receptor Agonist, 5′-Chloro-5′-Deoxy-(±)-ENBA Underlies its Tremorolytic Effect in the Harmaline-Induced Model of Essential Tremor

Autor: Jolanta Konieczny, Tomasz Lenda, Krystyna Ossowska, Klemencja Berghauzen-Maciejewska, Barbara Kosmowska, Jadwiga Wardas

Publikováno v: Neuroscience. 429:106-118

The primary cause of harmaline tremor, which is a model of essential tremor (ET) in animals, is excessive activation of olivocerebellar glutamatergic climbing fibers. Our recent study indicated that 5′-chloro-5′-deoxy-(±)-N6-(±)-(endo-norborn-2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c667f65745b81100fdd992a303a4537
https://doi.org/10.1016/j.neuroscience.2019.12.045

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Antiparkinsonian-like effects of CPL500036, a novel selective inhibitor of phosphodiesterase 10A, in the unilateral rat model of Parkinson's disease

Autor: Klemencja Berghauzen-Maciejewska, Tomasz Lenda, Jolanta Konieczny, Maciej Wieczorek, Jerzy Pieczykolan, Krystyna Ossowska, Mikołaj Matłoka

Publikováno v: European journal of pharmacology. 910

Phosphodiesterase 10A (PDE10A), the enzyme which catalyzes hydrolysis of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), is located almost exclusively in striatal γ-amino-butyric acid (GABA)ergic medium spiny neurons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c72808b007fbcd7f0b9ac564b10dac03
https://pubmed.ncbi.nlm.nih.gov/34469756

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Adaptive down-regulation of the serotonin transporter in the 6-hydroxydopamine-induced rat model of preclinical stages of Parkinson’s disease and after chronic pramipexole treatment

Autor: Jadwiga Wardas, Klemencja Berghauzen-Maciejewska, Helena Domin, Barbara Kosmowska, Maria Śmiałowska, Krystyna Ossowska, Urszula Głowacka

Publikováno v: Neuroscience. 314:22-34

Our recent study has indicated that a moderate lesion induced by bilateral 6-hydroxydopamine (6-OHDA) injections into the ventrolateral region of the caudate-putamen (CP) in rats, modeling preclinical stages of Parkinson’s disease, induces a “dep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cf18bd095426cd674ffac9b0d397739
https://doi.org/10.1016/j.neuroscience.2015.11.049

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Pramipexole but not imipramine or fluoxetine reverses the 'depressive-like' behaviour in a rat model of preclinical stages of Parkinson's disease

Autor: Klemencja Berghauzen-Maciejewska, Jadwiga Wardas, Katarzyna Kuter, Anna Dziubina, Krystyna Ossowska, Wacław Kolasiewicz, Urszula Głowacka

Publikováno v: Behavioural Brain Research. 271:343-353

Depression is a frequent comorbid disorder in Parkinson's disease and may antedate its motor symptoms. However, mechanisms underlying Parkinson's disease-associated depression are unknown and its current medication is insufficient. The aim of the pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f6796b03068837a10d7bbc606ecac5b
https://doi.org/10.1016/j.bbr.2014.06.029

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Lu AF21934, a positive allosteric modulator of mGlu4 receptors, reduces the harmaline-induced hyperactivity but not tremor in rats

Autor: Stevin H. Zorn, Andrzej Pilc, Urszula Głowacka, Jadwiga Wardas, Dario Doller, Katarzyna Kuter, Klemencja Berghauzen-Maciejewska, Krystyna Ossowska

Publikováno v: Neuropharmacology. 83:28-35

Harmaline induces tremor in animals resembling essential tremor which has been suggested to result from activation of the glutamatergic olivo-cerebellar projection. The aim of the present study was to examine the effects of systemic administration of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f3c0368e9bff5119b70ea61c315691f
https://doi.org/10.1016/j.neuropharm.2014.03.018

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Alterations of BDNF and trkB mRNA Expression in the 6-Hydroxydopamine-Induced Model of Preclinical Stages of Parkinson’s Disease: An Influence of Chronic Pramipexole in Rats

Autor: Katarzyna Kuter, Jadwiga Wardas, Krystyna Ossowska, Klemencja Berghauzen-Maciejewska, Barbara Kosmowska, Urszula Głowacka

Publikováno v: PLoS ONE
PLoS ONE, Vol 10, Iss 3, p e0117698 (2015)

Our recent study has indicated that a moderate lesion of the mesostriatal and mesolimbic pathways in rats, modelling preclinical stages of Parkinson’s disease, induces a depressive-like behaviour which is reversed by chronic treatment with pramipex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff82df95ad407d3dd9c649dd7ff7f896
http://europepmc.org/articles/PMC4349741

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A partial lesion of the substantia nigra pars compacta and retrorubral field decreases the harmaline-induced glutamate release in the rat cerebellum

Autor: Klemencja Berghauzen-Maciejewska, Katarzyna Kamińska, Krystyna Gołembiowska, Krystyna Ossowska, Anna Górska

Publikováno v: Brain research. 1537

The aim of the present study was to examine the influence of a partial lesion of both the substantia nigra pars compacta (SNC) and retrorubral field (RRF) on the glutamatergic transmission in the cerebellum and tremor induced by harmaline in rats. 6-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d288c0d9067f51398ac9ab34a09cde0c
https://pubmed.ncbi.nlm.nih.gov/24012623

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6-OHDA injections into A8-A9 dopaminergic neurons modelling early stages of Parkinson's disease increase the harmaline-induced tremor in rats

Autor: Wacław Kolasiewicz, Krystyna Ossowska, Katarzyna Kuter, G Schulze, Przemysław Nowak, Klemencja Berghauzen

Publikováno v: Brain research. 1477

The aim of the present study was to examine the influence of a unilateral 6-hydroxydopamine (6-OHDA)-induced partial lesion of both the substantia nigra pars compacta (SNc, A9) and retrorubral field (RRF, A8) on the tremor evoked by harmaline. 6-OHDA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dafd7c3c8172325ac90e288227395dd
https://pubmed.ncbi.nlm.nih.gov/22902616

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