Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kleiton S Borges"'
Autor:
Emanuele Pignatti, Sining Leng, Yixing Yuchi, Kleiton S. Borges, Nick A. Guagliardo, Manasvi S. Shah, Gerard Ruiz-Babot, Dulanjalee Kariyawasam, Makoto Mark Taketo, Ji Miao, Paula Q. Barrett, Diana L. Carlone, David T. Breault
Publikováno v:
Cell Reports, Vol 31, Iss 3, Pp - (2020)
Summary: Activating mutations in the canonical Wnt/β-catenin pathway are key drivers of hyperplasia, the gateway for tumor development. In a wide range of tissues, this occurs primarily through enhanced effects on cellular proliferation. Whether add
Externí odkaz:
https://doaj.org/article/475eba2b900146b99eaa1eb277eefd2f
Autor:
Dipika R. Mohan, Kleiton S. Borges, Isabella Finco, Christopher R. LaPensee, Juilee Rege, April L. Solon, Donald W. Little, Tobias Else, Madson Q. Almeida, Derek Dang, James Haggerty-Skeans, April A. Apfelbaum, Michelle Vinco, Alda Wakamatsu, Beatriz M. P. Mariani, Larissa Costa. Amorim, Ana Claudia. Latronico, Berenice B. Mendonca, Maria Claudia N. Zerbini, Elizabeth R. Lawlor, Ryoma Ohi, Richard J. Auchus, William E. Rainey, Suely K.N. Marie, Thomas J. Giordano, Sriram Venneti, Maria Candida Barisson Villares Fragoso, David T. Breault, Antonio Marcondes. Lerario, Gary D. Hammer
Publikováno v:
Cancer Research.
Adrenocortical carcinoma (ACC) is a rare cancer in which tissue-specific differentiation is paradoxically associated with dismal outcomes. The differentiated ACC subtype CIMP-high is prevalent, incurable, and routinely fatal. CIMP-high ACC possess ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be9890ecf1e233fe62894cabb8c7c08c
https://doi.org/10.1158/0008-5472.can-22-2712
https://doi.org/10.1158/0008-5472.can-22-2712
β-catenin programs a tissue-specific epigenetic vulnerability in aggressive adrenocortical carcinoma
Autor:
Dipika R. Mohan, Kleiton S. Borges, Isabella Finco, Christopher R. LaPensee, Juilee Rege, April L. Solon, Donald W. Little, Tobias Else, Madson Q. Almeida, Derek Dang, James Haggerty-Skeans, April A. Apfelbaum, Michelle Vinco, Alda Wakamatsu, Beatriz MP Mariani, Larissa Amorin, Ana Claudia Latronico, Berenice B. Mendonca, Maria Claudia N. Zerbini, Elizabeth R. Lawlor, Ryoma Ohi, Richard J. Auchus, William E. Rainey, Suely K. N. Marie, Thomas J. Giordano, Sriram Venneti, Maria Candida B. V. Fragoso, David T. Breault, Antonio Marcondes Lerario, Gary D. Hammer
Adrenocortical carcinoma (ACC) is a rare cancer in which tissue-specific differentiation is paradoxically associated with dismal outcomes. The differentiated ACC subtype CIMP-high is prevalent, incurable, and routinely fatal. CIMP-high ACC possess ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9810854af32882553cc7a6cfe3b60b1e
https://doi.org/10.1101/2022.07.02.497654
https://doi.org/10.1101/2022.07.02.497654
Publikováno v:
Clinical Medicine Insights: Oncology, Vol 2014, Iss 8, Pp 95-100 (2014)
Externí odkaz:
https://doaj.org/article/0e1d29034b9242778df2bd408dfc2bd9
Autor:
Dipika R. Mohan, Kleiton S. Borges, Isabella Finco, Christopher R. LaPensee, Juilee Rege, Donald W. Little, Tobias Else, Madson Q. Almeida, Derek Dang, James Haggerty-Skeans, Ana Claudia Latronico, Berenice B. Mendonca, Richard J. Auchus, William E. Rainey, Suely K. Marie, Thomas J. Giordano, Sriram Venneti, Maria Candida B. Fragoso, David T. Breault, Antonio M. Lerario, Gary D. Hammer
Publikováno v:
Cancer Research. 83:1501-1501
Adrenocortical carcinoma (ACC) is a rare cancer of the adrenal cortex without curative medical therapies. CIMP-high is an aggressive ACC molecular subtype defined by global CpG island hypermethylation with paradoxical activation of adrenal differenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::089c1fa715cd4f01e3e83126f29d3e12
https://doi.org/10.1158/1538-7445.am2023-1501
https://doi.org/10.1158/1538-7445.am2023-1501
Autor:
Christopher R. LaPensee, Amy E. O’Connell, Donald W. Little, Kleiton S Borges, Gary D. Hammer, David T. Breault, Kaitlin J. Basham
Publikováno v:
Journal of the Endocrine Society
Dysregulation of normal adrenal structure and function contributes to a spectrum of diseases from hypoplasia to cancer. Peripheral adrenocortical progenitor cells in the zona glomerulosa (zG) centripetally migrate and differentiate to replenish stero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d9c597e55d8e21700e10449bbde30cd
https://doi.org/10.1210/jendso/bvab048.149
https://doi.org/10.1210/jendso/bvab048.149
Autor:
Luiz Gonzaga Tone, Vitor M. Faça, Annabel Berthon, Andrea Gutierrez Maria, Fabio R. Faucz, Kleiton S Borges, Carolina Hassibe Thomé, Ludivine Drougat, Constantine Stratakis, Régia Caroline Peixoto Lira
Publikováno v:
Cancer Research. 81:412-412
Adrenocortical cancer (ACC) is a rare and aggressive type of endocrine tumor with high risk of recurrence and metastasis. The overall survival of patients diagnosed with ACC is very low and current treatment for metastatic stages remain limited to mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d33e490cc7a1c58ef2e0d5176b1e9be6
https://doi.org/10.1158/1538-7445.am2021-412
https://doi.org/10.1158/1538-7445.am2021-412
Autor:
Augusto Faria Andrade, Kleiton S Borges, Veridiana K. Suazo, Carlos Alberto Scrideli, Luiz Gonzaga Tone, Rosane G.P. Queiroz
Publikováno v:
European Journal of Cancer. 50:S107
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a64b03291073043f882d23f7efdd9558
https://doi.org/10.1016/s0959-8049(14)50397-8
https://doi.org/10.1016/s0959-8049(14)50397-8