Combination of Photodynamic Therapy and Immune Checkpoint Blockade.

Autor: Kleinovink JW; Department of Immunology, Tumor Immunology group, Leiden University Medical Center, Leiden, The Netherlands., Ossendorp F; Department of Immunology, Tumor Immunology group, Leiden University Medical Center, Leiden, The Netherlands. F.A.OSSENDORP@LUMC.NL.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2022; Vol. 2451, pp. 589-596.

IL-6 signaling in macrophages is required for immunotherapy-driven regression of tumors.

Autor: Beyranvand Nejad E; Medical Oncology, Oncode institute, Leiden University Medical Center, Leiden, Zuid-Holland, The Netherlands., Labrie C; Medical Oncology, Oncode institute, Leiden University Medical Center, Leiden, Zuid-Holland, The Netherlands., van Elsas MJ; Medical Oncology, Oncode institute, Leiden University Medical Center, Leiden, Zuid-Holland, The Netherlands., Kleinovink JW; Medical Oncology, Oncode institute, Leiden University Medical Center, Leiden, Zuid-Holland, The Netherlands., Mittrücker HW; Department of Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Franken KLMC; Department of Immunology, Leiden University Medical Center, Leiden, Zuid-Holland, The Netherlands., Heink S; Experimental Neuroimmunology, Technische Universität München, Munchen, Bayern, Germany., Korn T; Experimental Neuroimmunology, Technische Universität München, Munchen, Bayern, Germany., Arens R; Department of Immunology, Leiden University Medical Center, Leiden, Zuid-Holland, The Netherlands., van Hall T; Medical Oncology, Oncode institute, Leiden University Medical Center, Leiden, Zuid-Holland, The Netherlands., van der Burg SH; Medical Oncology, Oncode institute, Leiden University Medical Center, Leiden, Zuid-Holland, The Netherlands shvdburg@lumc.nl.

Publikováno v: Journal for immunotherapy of cancer [J Immunother Cancer] 2021 Apr; Vol. 9 (4).

Host genetics and tumor environment determine the functional impact of neutrophils in mouse tumor models.

Autor: van Elsas M; Medical Oncology, Oncode institute, Leiden University Medical Center, Leiden, The Netherlands., Kleinovink JW; Medical Oncology, Oncode institute, Leiden University Medical Center, Leiden, The Netherlands., Moerland M; Centre for Human Drug Research, Leiden, The Netherlands., Feiss G; Cutanea Life Sciences, Wayne, Pennsylvania, USA., Beyrend G; Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands., Arens R; Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands., Mei H; Sequencing Analysis Support Core, Leiden University Medical Center, Leiden, The Netherlands., Nibbering PH; Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands., Jirka SM; Centre for Human Drug Research, Leiden, The Netherlands., van Hall T; Medical Oncology, Oncode institute, Leiden University Medical Center, Leiden, The Netherlands., van der Burg SH; Medical Oncology, Oncode institute, Leiden University Medical Center, Leiden, The Netherlands shvdburg@lumc.nl.

Publikováno v: Journal for immunotherapy of cancer [J Immunother Cancer] 2020 Sep; Vol. 8 (2).

A Dual-Color Bioluminescence Reporter Mouse for Simultaneous in vivo Imaging of T Cell Localization and Function.

Autor: Kleinovink JW; Department of Immunohematology and Blood Transfusion, Tumor Immunology, Leiden University Medical Center, Leiden, Netherlands., Mezzanotte L; Department of Radiology and Nuclear Medicine, Optical Molecular Imaging, Erasmus Medical Center, Rotterdam, Netherlands.; Department of Molecular Genetics, Erasmus Medical Center Rotterdam, Netherlands., Zambito G; Department of Radiology and Nuclear Medicine, Optical Molecular Imaging, Erasmus Medical Center, Rotterdam, Netherlands.; Department of Molecular Genetics, Erasmus Medical Center Rotterdam, Netherlands.; Medres, Cologne, Germany., Fransen MF; Department of Immunohematology and Blood Transfusion, Tumor Immunology, Leiden University Medical Center, Leiden, Netherlands., Cruz LJ; Translational Nanobiomaterials and Imaging, Department of Radiology, Leiden University Medical Center, Leiden, Netherlands., Verbeek JS; Department of Human Genetics, Leiden University Medical Center, Leiden, Netherlands., Chan A; Percuros B.V., Enschede, Netherlands., Ossendorp F; Department of Immunohematology and Blood Transfusion, Tumor Immunology, Leiden University Medical Center, Leiden, Netherlands., Löwik C; Department of Radiology and Nuclear Medicine, Optical Molecular Imaging, Erasmus Medical Center, Rotterdam, Netherlands.; Department of Molecular Genetics, Erasmus Medical Center Rotterdam, Netherlands.; Department of Oncology, CHUV Lausanne University Hospital, Lausanne, Switzerland.

Publikováno v: Frontiers in immunology [Front Immunol] 2019 Jan 08; Vol. 9, pp. 3097. Date of Electronic Publication: 2019 Jan 08 (Print Publication: 2018).

A Restricted Role for FcγR in the Regulation of Adaptive Immunity.

Autor: Fransen MF; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands., Benonisson H; Department of Human Genetics, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands., van Maren WW; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands., Sow HS; Department of Human Genetics, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands., Breukel C; Department of Human Genetics, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands., Linssen MM; Department of Human Genetics, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands., Claassens JWC; Department of Human Genetics, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands., Brouwers C; Department of Human Genetics, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands., van der Kaa J; Department of Human Genetics, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands., Camps M; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands., Kleinovink JW; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands., Vonk KK; Department of Human Genetics, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands., van Heiningen S; Department of Human Genetics, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands., Klar N; Department of Nephrology, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands., van Beek L; Department of Human Genetics, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands., van Harmelen V; Department of Human Genetics, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands., Daxinger L; Department of Human Genetics, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands., Nandakumar KS; Department of Medical Biochemistry and Biophysics, Karolinska Institute, 17177 Stockholm, Sweden.; School of Pharmaceutical Sciences, Southern Medical University, 510515 Guangzhou, China., Holmdahl R; Department of Medical Biochemistry and Biophysics, Karolinska Institute, 17177 Stockholm, Sweden., Coward C; Department of Veterinary Medicine, University of Cambridge, Cambridge CB3 0ES, United Kingdom., Lin Q; Department of Pathology, Juntendo University School of Medicine, Tokyo 113-8421, Japan., Hirose S; Toin Human Science and Technology Center, Department of Biomedical Engineering, Toin University of Yokohama, Yokohama 225-8502, Japan., Salvatori D; Department of Anatomy, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands; and., van Hall T; Department of Clinical Oncology, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands., van Kooten C; Department of Nephrology, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands., Mastroeni P; Department of Veterinary Medicine, University of Cambridge, Cambridge CB3 0ES, United Kingdom., Ossendorp F; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands., Verbeek JS; Department of Human Genetics, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands; j.s.verbeek@lumc.nl.

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2018 Apr 15; Vol. 200 (8), pp. 2615-2626. Date of Electronic Publication: 2018 Mar 09.